| Full name: lysine acetyltransferase 6B | Alias Symbol: querkopf|qkf|Morf|MOZ2|ZC2HC6B | ||
| Type: protein-coding gene | Cytoband: 10q22.2 | ||
| Entrez ID: 23522 | HGNC ID: HGNC:17582 | Ensembl Gene: ENSG00000156650 | OMIM ID: 605880 |
| Drug and gene relationship at DGIdb | |||
Expression of KAT6B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | KAT6B | 23522 | 212462_at | -0.7615 | 0.1641 | |
| GSE20347 | KAT6B | 23522 | 212462_at | -0.3701 | 0.0225 | |
| GSE23400 | KAT6B | 23522 | 212462_at | -0.3633 | 0.0003 | |
| GSE26886 | KAT6B | 23522 | 212462_at | -0.1228 | 0.7188 | |
| GSE29001 | KAT6B | 23522 | 212462_at | -0.3331 | 0.1571 | |
| GSE38129 | KAT6B | 23522 | 212462_at | -0.5544 | 0.0009 | |
| GSE45670 | KAT6B | 23522 | 212462_at | -0.7360 | 0.0001 | |
| GSE53622 | KAT6B | 23522 | 925 | -0.7823 | 0.0000 | |
| GSE53624 | KAT6B | 23522 | 925 | -0.4768 | 0.0000 | |
| GSE63941 | KAT6B | 23522 | 212462_at | -1.3782 | 0.0033 | |
| GSE77861 | KAT6B | 23522 | 212462_at | -0.1303 | 0.5580 | |
| GSE97050 | KAT6B | 23522 | A_23_P388855 | -1.0479 | 0.0887 | |
| SRP007169 | KAT6B | 23522 | RNAseq | 0.5683 | 0.2081 | |
| SRP008496 | KAT6B | 23522 | RNAseq | 0.4875 | 0.0999 | |
| SRP064894 | KAT6B | 23522 | RNAseq | -0.6613 | 0.0014 | |
| SRP133303 | KAT6B | 23522 | RNAseq | -0.5204 | 0.0001 | |
| SRP159526 | KAT6B | 23522 | RNAseq | -0.4937 | 0.2464 | |
| SRP193095 | KAT6B | 23522 | RNAseq | -0.4028 | 0.0065 | |
| SRP219564 | KAT6B | 23522 | RNAseq | -0.3565 | 0.4200 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by KAT6B expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of KAT6B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | KAT6B | 23522 | 3 | 5 | 22 | |
| GSE20123 | KAT6B | 23522 | 3 | 4 | 23 | |
| GSE43470 | KAT6B | 23522 | 2 | 8 | 33 | |
| GSE46452 | KAT6B | 23522 | 0 | 11 | 48 | |
| GSE47630 | KAT6B | 23522 | 2 | 14 | 24 | |
| GSE54993 | KAT6B | 23522 | 7 | 0 | 63 | |
| GSE54994 | KAT6B | 23522 | 2 | 11 | 40 | |
| GSE60625 | KAT6B | 23522 | 0 | 0 | 11 | |
| GSE74703 | KAT6B | 23522 | 2 | 5 | 29 | |
| GSE74704 | KAT6B | 23522 | 1 | 2 | 17 | |
| TCGA | KAT6B | 23522 | 11 | 23 | 62 |
Total number of gains: 33; Total number of losses: 83; Total Number of normals: 372.
Somatic mutations of KAT6B:
Generating mutation plots.
Highly correlated genes for KAT6B:
Showing top 20/1191 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| KAT6B | C1QTNF7 | 0.798595 | 4 | 0 | 4 |
| KAT6B | C3orf70 | 0.773573 | 4 | 0 | 4 |
| KAT6B | ANAPC16 | 0.773025 | 4 | 0 | 4 |
| KAT6B | CLYBL | 0.769743 | 5 | 0 | 5 |
| KAT6B | FRMD3 | 0.753766 | 4 | 0 | 4 |
| KAT6B | PDCD4 | 0.752197 | 3 | 0 | 3 |
| KAT6B | GNG7 | 0.751512 | 5 | 0 | 5 |
| KAT6B | SLC4A4 | 0.737666 | 5 | 0 | 5 |
| KAT6B | FNIP2 | 0.733453 | 3 | 0 | 3 |
| KAT6B | KANSL3 | 0.730558 | 3 | 0 | 3 |
| KAT6B | AFF3 | 0.727351 | 4 | 0 | 3 |
| KAT6B | CBX7 | 0.725557 | 8 | 0 | 7 |
| KAT6B | DYNLL2 | 0.721567 | 3 | 0 | 3 |
| KAT6B | ITGA9 | 0.720855 | 5 | 0 | 4 |
| KAT6B | RASSF3 | 0.720052 | 4 | 0 | 3 |
| KAT6B | CAMTA1 | 0.719051 | 3 | 0 | 3 |
| KAT6B | NFIA | 0.715026 | 5 | 0 | 4 |
| KAT6B | FRY | 0.712737 | 9 | 0 | 8 |
| KAT6B | KIAA2026 | 0.711901 | 4 | 0 | 4 |
| KAT6B | NFIX | 0.71035 | 7 | 0 | 6 |
For details and further investigation, click here
