| Full name: TBC1 domain family member 16 | Alias Symbol: MGC25062|FLJ20748 | ||
| Type: protein-coding gene | Cytoband: 17q25.3 | ||
| Entrez ID: 125058 | HGNC ID: HGNC:28356 | Ensembl Gene: ENSG00000167291 | OMIM ID: 616637 |
| Drug and gene relationship at DGIdb | |||
Expression of TBC1D16:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TBC1D16 | 125058 | 222116_s_at | 0.8988 | 0.1306 | |
| GSE20347 | TBC1D16 | 125058 | 222116_s_at | 0.4739 | 0.0032 | |
| GSE23400 | TBC1D16 | 125058 | 222116_s_at | 0.2385 | 0.0021 | |
| GSE26886 | TBC1D16 | 125058 | 222116_s_at | 0.6114 | 0.0101 | |
| GSE29001 | TBC1D16 | 125058 | 222116_s_at | 0.7147 | 0.0428 | |
| GSE38129 | TBC1D16 | 125058 | 222116_s_at | 0.2577 | 0.2352 | |
| GSE45670 | TBC1D16 | 125058 | 222116_s_at | 0.3864 | 0.0615 | |
| GSE53622 | TBC1D16 | 125058 | 89882 | 0.2106 | 0.0528 | |
| GSE53624 | TBC1D16 | 125058 | 89882 | 0.7033 | 0.0000 | |
| GSE63941 | TBC1D16 | 125058 | 222116_s_at | -1.7816 | 0.0051 | |
| GSE77861 | TBC1D16 | 125058 | 228488_at | 0.4234 | 0.0779 | |
| GSE97050 | TBC1D16 | 125058 | A_33_P3241937 | 0.1820 | 0.5664 | |
| SRP007169 | TBC1D16 | 125058 | RNAseq | 0.8413 | 0.0377 | |
| SRP008496 | TBC1D16 | 125058 | RNAseq | 1.1991 | 0.0015 | |
| SRP064894 | TBC1D16 | 125058 | RNAseq | 0.6366 | 0.0017 | |
| SRP133303 | TBC1D16 | 125058 | RNAseq | 0.2992 | 0.1019 | |
| SRP159526 | TBC1D16 | 125058 | RNAseq | 0.6449 | 0.0176 | |
| SRP193095 | TBC1D16 | 125058 | RNAseq | 1.2544 | 0.0000 | |
| SRP219564 | TBC1D16 | 125058 | RNAseq | 0.7346 | 0.0110 | |
| TCGA | TBC1D16 | 125058 | RNAseq | -0.1422 | 0.0423 |
Upregulated datasets: 2; Downregulated datasets: 1.
Survival by TBC1D16 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TBC1D16:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TBC1D16 | 125058 | 4 | 3 | 23 | |
| GSE20123 | TBC1D16 | 125058 | 4 | 3 | 23 | |
| GSE43470 | TBC1D16 | 125058 | 2 | 6 | 35 | |
| GSE46452 | TBC1D16 | 125058 | 34 | 0 | 25 | |
| GSE47630 | TBC1D16 | 125058 | 9 | 1 | 30 | |
| GSE54993 | TBC1D16 | 125058 | 2 | 5 | 63 | |
| GSE54994 | TBC1D16 | 125058 | 10 | 6 | 37 | |
| GSE60625 | TBC1D16 | 125058 | 6 | 0 | 5 | |
| GSE74703 | TBC1D16 | 125058 | 2 | 4 | 30 | |
| GSE74704 | TBC1D16 | 125058 | 4 | 3 | 13 | |
| TCGA | TBC1D16 | 125058 | 29 | 9 | 58 |
Total number of gains: 106; Total number of losses: 40; Total Number of normals: 342.
Somatic mutations of TBC1D16:
Generating mutation plots.
Highly correlated genes for TBC1D16:
Showing top 20/1098 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TBC1D16 | HPS4 | 0.793081 | 3 | 0 | 3 |
| TBC1D16 | ZNF71 | 0.792343 | 3 | 0 | 3 |
| TBC1D16 | ELOF1 | 0.778346 | 3 | 0 | 3 |
| TBC1D16 | CEP41 | 0.771369 | 3 | 0 | 3 |
| TBC1D16 | SNRPF | 0.749392 | 3 | 0 | 3 |
| TBC1D16 | BAK1 | 0.738614 | 3 | 0 | 3 |
| TBC1D16 | SIDT2 | 0.737396 | 3 | 0 | 3 |
| TBC1D16 | EBF1 | 0.736058 | 3 | 0 | 3 |
| TBC1D16 | LINGO1 | 0.727002 | 3 | 0 | 3 |
| TBC1D16 | EGLN2 | 0.724321 | 3 | 0 | 3 |
| TBC1D16 | FGF7 | 0.720367 | 4 | 0 | 4 |
| TBC1D16 | ABI2 | 0.718756 | 3 | 0 | 3 |
| TBC1D16 | CLU | 0.717961 | 3 | 0 | 3 |
| TBC1D16 | FOXC2 | 0.716676 | 3 | 0 | 3 |
| TBC1D16 | ZFP1 | 0.715366 | 4 | 0 | 4 |
| TBC1D16 | HYLS1 | 0.715064 | 3 | 0 | 3 |
| TBC1D16 | GDAP1 | 0.713093 | 3 | 0 | 3 |
| TBC1D16 | ELMO1 | 0.712229 | 3 | 0 | 3 |
| TBC1D16 | ARHGAP17 | 0.711863 | 3 | 0 | 3 |
| TBC1D16 | RASD1 | 0.710175 | 3 | 0 | 3 |
For details and further investigation, click here
