DHTKD1

 

Full name: dehydrogenase E1 and transketolase domain containing 1 Alias Symbol: KIAA1630|MGC3090|DKFZP762M115|CMT2Q
Type: protein-coding gene Cytoband: 10p14
Entrez ID: 55526 HGNC ID: HGNC:23537 Ensembl Gene: ENSG00000181192 OMIM ID: 614984
Drug and gene relationship at DGIdb

 

Expression of DHTKD1:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 DHTKD1 55526 227094_at 0.8141 0.0286
GSE20347 DHTKD1 55526 209916_at 0.5139 0.0116
GSE23400 DHTKD1 55526 209916_at 0.3883 0.0000
GSE26886 DHTKD1 55526 227094_at 0.3424 0.1245
GSE29001 DHTKD1 55526 209916_at 0.3114 0.4185
GSE38129 DHTKD1 55526 209916_at 0.5377 0.0011
GSE45670 DHTKD1 55526 227094_at 0.4627 0.0101
GSE53622 DHTKD1 55526 22429 0.3033 0.0011
GSE53624 DHTKD1 55526 22429 0.4867 0.0000
GSE63941 DHTKD1 55526 227094_at 0.9422 0.1217
GSE77861 DHTKD1 55526 227094_at 0.1986 0.6917
GSE97050 DHTKD1 55526 A_24_P722216 0.1995 0.5707
SRP007169 DHTKD1 55526 RNAseq 0.3740 0.3487
SRP008496 DHTKD1 55526 RNAseq 0.1622 0.5282
SRP064894 DHTKD1 55526 RNAseq 0.2615 0.1547
SRP133303 DHTKD1 55526 RNAseq 0.0681 0.6467
SRP159526 DHTKD1 55526 RNAseq 0.2421 0.2923
SRP193095 DHTKD1 55526 RNAseq 0.1832 0.0558
SRP219564 DHTKD1 55526 RNAseq 0.0646 0.8204
TCGA DHTKD1 55526 RNAseq 0.0368 0.6161

Upregulated datasets: 0; Downregulated datasets: 0.  

 

Survival by DHTKD1 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of DHTKD1:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 DHTKD1 55526 6 7 17
GSE20123 DHTKD1 55526 6 6 18
GSE43470 DHTKD1 55526 3 5 35
GSE46452 DHTKD1 55526 2 14 43
GSE47630 DHTKD1 55526 6 14 20
GSE54993 DHTKD1 55526 11 0 59
GSE54994 DHTKD1 55526 4 10 39
GSE60625 DHTKD1 55526 0 0 11
GSE74703 DHTKD1 55526 2 3 31
GSE74704 DHTKD1 55526 1 5 14
TCGA DHTKD1 55526 19 24 53

Total number of gains: 60; Total number of losses: 88; Total Number of normals: 340.  

 

Somatic mutations of DHTKD1:

 

Generating mutation plots.

 

Highly correlated genes for DHTKD1:

 

Showing top 20/991 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
DHTKD1RRM2B0.836649303
DHTKD1ZGPAT0.781602303
DHTKD1TPD52L20.774188303
DHTKD1TRIM590.76929303
DHTKD1PACS10.762505303
DHTKD1LRRC580.743486404
DHTKD1NAA250.740405303
DHTKD1GDAP10.734484303
DHTKD1GPR1580.723839403
DHTKD1NRM0.720326504
DHTKD1SPTSSA0.706363303
DHTKD1NFXL10.705286403
DHTKD1SBNO10.703825303
DHTKD1CDCA20.702305504
DHTKD1GRB20.702169303
DHTKD1C11orf800.695321404
DHTKD1RNF40.69442403
DHTKD1PPP2R2D0.693137303
DHTKD1COPA0.691607303
DHTKD1TANC20.690535403

For details and further investigation, click here