SULT1A1

 

Full name: sulfotransferase family 1A member 1 Alias Symbol: P-PST
Type: protein-coding gene Cytoband: 16p11.2
Entrez ID: 6817 HGNC ID: HGNC:11453 Ensembl Gene: ENSG00000196502 OMIM ID: 171150
Drug and gene relationship at DGIdb

 

Expression of SULT1A1:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 SULT1A1 6817 215299_x_at 0.4313 0.3377
GSE20347 SULT1A1 6817 203615_x_at 0.6220 0.0008
GSE23400 SULT1A1 6817 203615_x_at 0.4201 0.0000
GSE26886 SULT1A1 6817 203615_x_at 0.8320 0.0006
GSE29001 SULT1A1 6817 203615_x_at 0.4251 0.0854
GSE38129 SULT1A1 6817 215299_x_at 0.4325 0.0607
GSE45670 SULT1A1 6817 215299_x_at 0.1417 0.5722
GSE63941 SULT1A1 6817 203615_x_at 0.7027 0.2601
GSE77861 SULT1A1 6817 203615_x_at 0.7752 0.0102
SRP064894 SULT1A1 6817 RNAseq 0.3161 0.4108
SRP133303 SULT1A1 6817 RNAseq -0.2153 0.4032
SRP159526 SULT1A1 6817 RNAseq 0.8256 0.0505
SRP193095 SULT1A1 6817 RNAseq 0.4162 0.0672
SRP219564 SULT1A1 6817 RNAseq 0.3670 0.4712
TCGA SULT1A1 6817 RNAseq -0.5113 0.0027

Upregulated datasets: 0; Downregulated datasets: 0.  


 

Survival by SULT1A1 expression:

 

TCGA

 

Note: Click image to view full size file.  


Copy number change of SULT1A1:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 SULT1A1 6817 5 5 20
GSE20123 SULT1A1 6817 5 4 21
GSE43470 SULT1A1 6817 4 3 36
GSE46452 SULT1A1 6817 38 1 20
GSE47630 SULT1A1 6817 11 7 22
GSE54993 SULT1A1 6817 3 5 62
GSE54994 SULT1A1 6817 4 9 40
GSE60625 SULT1A1 6817 4 0 7
GSE74703 SULT1A1 6817 4 2 30
GSE74704 SULT1A1 6817 3 2 15
TCGA SULT1A1 6817 20 12 64

Total number of gains: 101; Total number of losses: 50; Total Number of normals: 337.  


 

Somatic mutations of SULT1A1:

 

Generating mutation plots.

 

Highly correlated genes for SULT1A1:

 

Showing top 20/450 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
SULT1A1SULT1A20.8543651009
SULT1A1SPSB20.815927303
SULT1A1RASSF60.765504303
SULT1A1MAP3K130.762167303
SULT1A1QRFPR0.745922303
SULT1A1GDPD10.718544303
SULT1A1EIF2AK40.701705403
SULT1A1NMNAT30.690474303
SULT1A1SCYL10.689782303
SULT1A1TMEM2160.684803303
SULT1A1FLVCR10.684368404
SULT1A1LYPD6B0.684222303
SULT1A1LTBR0.682745403
SULT1A1NAV10.677463303
SULT1A1ZNF5260.671065303
SULT1A1CABLES20.670967303
SULT1A1LOXL40.669107303
SULT1A1HSD17B10.664647303
SULT1A1PIGX0.661945403
SULT1A1C1orf1150.659823605

For details and further investigation, click here