| Full name: frizzled class receptor 7 | Alias Symbol: FzE3 | ||
| Type: protein-coding gene | Cytoband: 2q33.1 | ||
| Entrez ID: 8324 | HGNC ID: HGNC:4045 | Ensembl Gene: ENSG00000155760 | OMIM ID: 603410 |
| Drug and gene relationship at DGIdb | |||
FZD7 involved pathways:
Expression of FZD7:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FZD7 | 8324 | 203706_s_at | -0.6785 | 0.5379 | |
| GSE20347 | FZD7 | 8324 | 203706_s_at | 1.0448 | 0.0676 | |
| GSE23400 | FZD7 | 8324 | 203706_s_at | 0.5502 | 0.0192 | |
| GSE26886 | FZD7 | 8324 | 203706_s_at | 1.0176 | 0.1291 | |
| GSE29001 | FZD7 | 8324 | 203705_s_at | 0.5711 | 0.3204 | |
| GSE38129 | FZD7 | 8324 | 203706_s_at | 0.8699 | 0.0688 | |
| GSE45670 | FZD7 | 8324 | 203706_s_at | -0.8253 | 0.2536 | |
| GSE53622 | FZD7 | 8324 | 90934 | 0.5842 | 0.0040 | |
| GSE53624 | FZD7 | 8324 | 90934 | 0.6023 | 0.0000 | |
| GSE63941 | FZD7 | 8324 | 203705_s_at | -3.2784 | 0.0002 | |
| GSE77861 | FZD7 | 8324 | 203706_s_at | 2.1624 | 0.0046 | |
| GSE97050 | FZD7 | 8324 | A_23_P209449 | -0.7627 | 0.1556 | |
| SRP007169 | FZD7 | 8324 | RNAseq | 2.8750 | 0.0000 | |
| SRP008496 | FZD7 | 8324 | RNAseq | 2.8430 | 0.0000 | |
| SRP064894 | FZD7 | 8324 | RNAseq | -0.0113 | 0.9522 | |
| SRP133303 | FZD7 | 8324 | RNAseq | 0.2306 | 0.4806 | |
| SRP159526 | FZD7 | 8324 | RNAseq | 2.0548 | 0.0006 | |
| SRP193095 | FZD7 | 8324 | RNAseq | 1.6292 | 0.0000 | |
| SRP219564 | FZD7 | 8324 | RNAseq | -0.3278 | 0.6844 | |
| TCGA | FZD7 | 8324 | RNAseq | 0.2571 | 0.0472 |
Upregulated datasets: 5; Downregulated datasets: 1.
Survival by FZD7 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FZD7:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FZD7 | 8324 | 7 | 4 | 19 | |
| GSE20123 | FZD7 | 8324 | 7 | 4 | 19 | |
| GSE43470 | FZD7 | 8324 | 1 | 1 | 41 | |
| GSE46452 | FZD7 | 8324 | 1 | 4 | 54 | |
| GSE47630 | FZD7 | 8324 | 4 | 5 | 31 | |
| GSE54993 | FZD7 | 8324 | 0 | 3 | 67 | |
| GSE54994 | FZD7 | 8324 | 10 | 9 | 34 | |
| GSE60625 | FZD7 | 8324 | 0 | 3 | 8 | |
| GSE74703 | FZD7 | 8324 | 1 | 1 | 34 | |
| GSE74704 | FZD7 | 8324 | 3 | 2 | 15 | |
| TCGA | FZD7 | 8324 | 21 | 11 | 64 |
Total number of gains: 55; Total number of losses: 47; Total Number of normals: 386.
Somatic mutations of FZD7:
Generating mutation plots.
Highly correlated genes for FZD7:
Showing top 20/633 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FZD7 | KLF2 | 0.881111 | 3 | 0 | 3 |
| FZD7 | MAN1C1 | 0.809071 | 3 | 0 | 3 |
| FZD7 | STARD9 | 0.80445 | 3 | 0 | 3 |
| FZD7 | SAT2 | 0.78885 | 4 | 0 | 4 |
| FZD7 | MTMR9 | 0.78426 | 3 | 0 | 3 |
| FZD7 | FNIP2 | 0.782987 | 3 | 0 | 3 |
| FZD7 | KCNT2 | 0.782945 | 4 | 0 | 4 |
| FZD7 | CXCL12 | 0.779247 | 3 | 0 | 3 |
| FZD7 | ASB5 | 0.774753 | 3 | 0 | 3 |
| FZD7 | FILIP1 | 0.772112 | 3 | 0 | 3 |
| FZD7 | ITIH5 | 0.770158 | 3 | 0 | 3 |
| FZD7 | PABPC5 | 0.769686 | 3 | 0 | 3 |
| FZD7 | MTRF1L | 0.758186 | 3 | 0 | 3 |
| FZD7 | IGIP | 0.758149 | 3 | 0 | 3 |
| FZD7 | GDPD1 | 0.753807 | 3 | 0 | 3 |
| FZD7 | DDAH2 | 0.741745 | 3 | 0 | 3 |
| FZD7 | UBE3A | 0.740316 | 3 | 0 | 3 |
| FZD7 | C3orf70 | 0.733938 | 4 | 0 | 4 |
| FZD7 | KIT | 0.729199 | 3 | 0 | 3 |
| FZD7 | SMOC2 | 0.729102 | 5 | 0 | 5 |
For details and further investigation, click here
