| Full name: golgi associated, gamma adaptin ear containing, ARF binding protein 1 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 22q13.1 | ||
| Entrez ID: 26088 | HGNC ID: HGNC:17842 | Ensembl Gene: ENSG00000100083 | OMIM ID: 606004 |
| Drug and gene relationship at DGIdb | |||
Expression of GGA1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GGA1 | 26088 | 45572_s_at | 0.0026 | 0.9955 | |
| GSE20347 | GGA1 | 26088 | 50277_at | 0.1085 | 0.4167 | |
| GSE23400 | GGA1 | 26088 | 50277_at | -0.0079 | 0.8756 | |
| GSE26886 | GGA1 | 26088 | 45572_s_at | 0.0110 | 0.9568 | |
| GSE29001 | GGA1 | 26088 | 45572_s_at | -0.2059 | 0.5751 | |
| GSE38129 | GGA1 | 26088 | 45572_s_at | 0.0235 | 0.8171 | |
| GSE45670 | GGA1 | 26088 | 45572_s_at | 0.1529 | 0.1862 | |
| GSE53622 | GGA1 | 26088 | 93431 | -0.3025 | 0.0000 | |
| GSE53624 | GGA1 | 26088 | 93431 | -0.3705 | 0.0000 | |
| GSE63941 | GGA1 | 26088 | 50277_at | 0.1512 | 0.6750 | |
| GSE77861 | GGA1 | 26088 | 45572_s_at | 0.1316 | 0.3568 | |
| GSE97050 | GGA1 | 26088 | A_23_P132294 | -0.1971 | 0.3225 | |
| SRP007169 | GGA1 | 26088 | RNAseq | -1.4798 | 0.0000 | |
| SRP008496 | GGA1 | 26088 | RNAseq | -1.5328 | 0.0000 | |
| SRP064894 | GGA1 | 26088 | RNAseq | 0.0838 | 0.6875 | |
| SRP133303 | GGA1 | 26088 | RNAseq | -0.5292 | 0.0002 | |
| SRP159526 | GGA1 | 26088 | RNAseq | -0.2191 | 0.5023 | |
| SRP193095 | GGA1 | 26088 | RNAseq | -0.0688 | 0.6001 | |
| SRP219564 | GGA1 | 26088 | RNAseq | -0.1564 | 0.5872 | |
| TCGA | GGA1 | 26088 | RNAseq | -0.0752 | 0.1025 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by GGA1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GGA1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GGA1 | 26088 | 6 | 5 | 19 | |
| GSE20123 | GGA1 | 26088 | 6 | 4 | 20 | |
| GSE43470 | GGA1 | 26088 | 4 | 6 | 33 | |
| GSE46452 | GGA1 | 26088 | 32 | 2 | 25 | |
| GSE47630 | GGA1 | 26088 | 9 | 4 | 27 | |
| GSE54993 | GGA1 | 26088 | 3 | 6 | 61 | |
| GSE54994 | GGA1 | 26088 | 9 | 8 | 36 | |
| GSE60625 | GGA1 | 26088 | 5 | 0 | 6 | |
| GSE74703 | GGA1 | 26088 | 4 | 4 | 28 | |
| GSE74704 | GGA1 | 26088 | 3 | 2 | 15 | |
| TCGA | GGA1 | 26088 | 27 | 15 | 54 |
Total number of gains: 108; Total number of losses: 56; Total Number of normals: 324.
Somatic mutations of GGA1:
Generating mutation plots.
Highly correlated genes for GGA1:
Showing top 20/150 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GGA1 | GRM8 | 0.678538 | 3 | 0 | 3 |
| GGA1 | NISCH | 0.672826 | 4 | 0 | 4 |
| GGA1 | MARK4 | 0.672182 | 5 | 0 | 4 |
| GGA1 | DMTN | 0.658246 | 4 | 0 | 4 |
| GGA1 | SRPK3 | 0.639347 | 4 | 0 | 4 |
| GGA1 | CASC15 | 0.638986 | 3 | 0 | 3 |
| GGA1 | MINK1 | 0.633682 | 3 | 0 | 3 |
| GGA1 | CIZ1 | 0.633264 | 3 | 0 | 3 |
| GGA1 | DEPDC5 | 0.63134 | 4 | 0 | 4 |
| GGA1 | FPR2 | 0.630693 | 3 | 0 | 3 |
| GGA1 | ST3GAL1 | 0.629889 | 3 | 0 | 3 |
| GGA1 | CYP2D6 | 0.628689 | 3 | 0 | 3 |
| GGA1 | PLEC | 0.627425 | 3 | 0 | 3 |
| GGA1 | FKBP8 | 0.626523 | 3 | 0 | 3 |
| GGA1 | ACBD4 | 0.624377 | 3 | 0 | 3 |
| GGA1 | RFPL3 | 0.618113 | 3 | 0 | 3 |
| GGA1 | NANOG | 0.616771 | 6 | 0 | 5 |
| GGA1 | GOLGA6L10 | 0.614141 | 3 | 0 | 3 |
| GGA1 | UBAP1L | 0.609013 | 3 | 0 | 3 |
| GGA1 | GPA33 | 0.606567 | 4 | 0 | 4 |
For details and further investigation, click here
