GKN2

 

Full name: gastrokine 2 Alias Symbol: TFIZ1|PRO813|VLTI465|blottin|GDDR|BRICD1B
Type: protein-coding gene Cytoband: 2p13.3
Entrez ID: 200504 HGNC ID: HGNC:24588 Ensembl Gene: ENSG00000183607 OMIM ID: 
Drug and gene relationship at DGIdb

 

Expression of GKN2:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 GKN2 200504 238222_at 0.0684 0.8306
GSE26886 GKN2 200504 238222_at -0.3516 0.0082
GSE45670 GKN2 200504 238222_at 0.1174 0.2945
GSE53622 GKN2 200504 27901 0.1983 0.6589
GSE53624 GKN2 200504 27901 0.1854 0.6513
GSE63941 GKN2 200504 238222_at 0.3006 0.0640
GSE77861 GKN2 200504 238222_at -0.0951 0.3845
TCGA GKN2 200504 RNAseq -6.8598 0.0000

Upregulated datasets: 0; Downregulated datasets: 1.  

 

Survival by GKN2 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of GKN2:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 GKN2 200504 11 0 19
GSE20123 GKN2 200504 11 0 19
GSE43470 GKN2 200504 6 0 37
GSE46452 GKN2 200504 2 3 54
GSE47630 GKN2 200504 7 0 33
GSE54993 GKN2 200504 0 6 64
GSE54994 GKN2 200504 12 0 41
GSE60625 GKN2 200504 0 3 8
GSE74703 GKN2 200504 6 0 30
GSE74704 GKN2 200504 9 0 11
TCGA GKN2 200504 36 2 58

Total number of gains: 100; Total number of losses: 14; Total Number of normals: 374.  

 

Somatic mutations of GKN2:

 

Generating mutation plots.

 

Highly correlated genes for GKN2:

 

Showing top 20/85 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
GKN2UGT2B150.801959303
GKN2CLDN180.776892303
GKN2LIPF0.738333403
GKN2GKN10.706692504
GKN2MUC60.674495303
GKN2CHGA0.66589303
GKN2NR0B20.662718403
GKN2GHRL0.661673303
GKN2REG3G0.657306303
GKN2TM4SF50.656317404
GKN2LINC013120.656222303
GKN2LGALS40.651989403
GKN2LINC002260.650387303
GKN2FAM170B-AS10.648378303
GKN2LINC009430.645289403
GKN2GATA6-AS10.640336403
GKN2GRIN2A0.638269303
GKN2CYLC10.632632303
GKN2VWA3A0.631587404
GKN2ACRV10.631208303

For details and further investigation, click here