| Full name: UDP glucuronosyltransferase family 2 member B15 | Alias Symbol: UGT2B8 | ||
| Type: protein-coding gene | Cytoband: 4q13.2 | ||
| Entrez ID: 7366 | HGNC ID: HGNC:12546 | Ensembl Gene: ENSG00000196620 | OMIM ID: 600069 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of UGT2B15:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | UGT2B15 | 7366 | 216687_x_at | 0.0157 | 0.9599 | |
| GSE20347 | UGT2B15 | 7366 | 216687_x_at | 0.0676 | 0.4552 | |
| GSE23400 | UGT2B15 | 7366 | 207392_x_at | 0.0407 | 0.4178 | |
| GSE26886 | UGT2B15 | 7366 | 216687_x_at | -0.0001 | 0.9990 | |
| GSE29001 | UGT2B15 | 7366 | 207392_x_at | -0.0518 | 0.7252 | |
| GSE38129 | UGT2B15 | 7366 | 216687_x_at | -0.1652 | 0.1828 | |
| GSE45670 | UGT2B15 | 7366 | 207392_x_at | 0.2565 | 0.0516 | |
| GSE53622 | UGT2B15 | 7366 | 160384 | -0.0620 | 0.8440 | |
| GSE53624 | UGT2B15 | 7366 | 160384 | -0.1719 | 0.5769 | |
| GSE63941 | UGT2B15 | 7366 | 207392_x_at | -0.0097 | 0.9624 | |
| GSE77861 | UGT2B15 | 7366 | 207392_x_at | 0.1052 | 0.5237 | |
| SRP133303 | UGT2B15 | 7366 | RNAseq | 0.1294 | 0.6638 | |
| TCGA | UGT2B15 | 7366 | RNAseq | -5.3124 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by UGT2B15 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of UGT2B15:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | UGT2B15 | 7366 | 1 | 11 | 18 | |
| GSE20123 | UGT2B15 | 7366 | 1 | 12 | 17 | |
| GSE43470 | UGT2B15 | 7366 | 0 | 13 | 30 | |
| GSE46452 | UGT2B15 | 7366 | 2 | 35 | 22 | |
| GSE47630 | UGT2B15 | 7366 | 0 | 31 | 9 | |
| GSE54993 | UGT2B15 | 7366 | 7 | 0 | 63 | |
| GSE54994 | UGT2B15 | 7366 | 1 | 9 | 43 | |
| GSE60625 | UGT2B15 | 7366 | 0 | 0 | 11 | |
| GSE74703 | UGT2B15 | 7366 | 0 | 11 | 25 | |
| GSE74704 | UGT2B15 | 7366 | 1 | 8 | 11 | |
| TCGA | UGT2B15 | 7366 | 18 | 26 | 52 |
Total number of gains: 31; Total number of losses: 156; Total Number of normals: 301.
Somatic mutations of UGT2B15:
Generating mutation plots.
Highly correlated genes for UGT2B15:
Showing top 20/82 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| UGT2B15 | GKN2 | 0.801959 | 3 | 0 | 3 |
| UGT2B15 | GC | 0.662739 | 5 | 0 | 4 |
| UGT2B15 | VSIG1 | 0.658332 | 3 | 0 | 3 |
| UGT2B15 | DMTN | 0.646527 | 3 | 0 | 3 |
| UGT2B15 | CLDN18 | 0.644046 | 7 | 0 | 6 |
| UGT2B15 | IRF4 | 0.62272 | 3 | 0 | 3 |
| UGT2B15 | PGC | 0.619962 | 7 | 0 | 5 |
| UGT2B15 | GKN1 | 0.618248 | 7 | 0 | 5 |
| UGT2B15 | HSF4 | 0.613124 | 3 | 0 | 3 |
| UGT2B15 | CTSE | 0.612752 | 7 | 0 | 5 |
| UGT2B15 | LGALS4 | 0.612302 | 6 | 0 | 6 |
| UGT2B15 | FUT9 | 0.610183 | 4 | 0 | 3 |
| UGT2B15 | HNF1B | 0.599487 | 5 | 0 | 4 |
| UGT2B15 | DNAJA4 | 0.59879 | 4 | 0 | 3 |
| UGT2B15 | TFF2 | 0.598546 | 4 | 0 | 4 |
| UGT2B15 | CHRM5 | 0.598283 | 5 | 0 | 5 |
| UGT2B15 | OPCML | 0.596902 | 3 | 0 | 3 |
| UGT2B15 | TFF1 | 0.594116 | 6 | 0 | 5 |
| UGT2B15 | GHRL | 0.59248 | 3 | 0 | 3 |
| UGT2B15 | SLC6A12 | 0.588482 | 3 | 0 | 3 |
For details and further investigation, click here
