| Full name: forkhead box K2 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 17q25.3 | ||
| Entrez ID: 3607 | HGNC ID: HGNC:6036 | Ensembl Gene: ENSG00000141568 | OMIM ID: 147685 |
| Drug and gene relationship at DGIdb | |||
Expression of FOXK2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FOXK2 | 3607 | 203064_s_at | 1.0860 | 0.0161 | |
| GSE20347 | FOXK2 | 3607 | 203064_s_at | 0.5747 | 0.0002 | |
| GSE23400 | FOXK2 | 3607 | 203064_s_at | 0.5406 | 0.0000 | |
| GSE26886 | FOXK2 | 3607 | 226224_at | 0.4836 | 0.0054 | |
| GSE29001 | FOXK2 | 3607 | 203064_s_at | 0.6434 | 0.0153 | |
| GSE38129 | FOXK2 | 3607 | 203064_s_at | 0.7111 | 0.0000 | |
| GSE45670 | FOXK2 | 3607 | 203064_s_at | 0.6625 | 0.0004 | |
| GSE53622 | FOXK2 | 3607 | 22557 | 0.7165 | 0.0000 | |
| GSE53624 | FOXK2 | 3607 | 59019 | 0.6960 | 0.0000 | |
| GSE63941 | FOXK2 | 3607 | 203064_s_at | 0.4214 | 0.2844 | |
| GSE77861 | FOXK2 | 3607 | 226224_at | 0.3503 | 0.0277 | |
| GSE97050 | FOXK2 | 3607 | A_23_P397969 | 0.1043 | 0.6536 | |
| SRP007169 | FOXK2 | 3607 | RNAseq | 1.1336 | 0.0050 | |
| SRP008496 | FOXK2 | 3607 | RNAseq | 0.8097 | 0.0040 | |
| SRP064894 | FOXK2 | 3607 | RNAseq | 0.7543 | 0.0000 | |
| SRP133303 | FOXK2 | 3607 | RNAseq | 0.6145 | 0.0000 | |
| SRP159526 | FOXK2 | 3607 | RNAseq | 0.8182 | 0.0005 | |
| SRP193095 | FOXK2 | 3607 | RNAseq | 0.5251 | 0.0000 | |
| SRP219564 | FOXK2 | 3607 | RNAseq | 0.2251 | 0.2836 | |
| TCGA | FOXK2 | 3607 | RNAseq | 0.1302 | 0.0037 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by FOXK2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FOXK2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FOXK2 | 3607 | 4 | 5 | 21 | |
| GSE20123 | FOXK2 | 3607 | 4 | 5 | 21 | |
| GSE43470 | FOXK2 | 3607 | 3 | 5 | 35 | |
| GSE46452 | FOXK2 | 3607 | 34 | 0 | 25 | |
| GSE47630 | FOXK2 | 3607 | 9 | 2 | 29 | |
| GSE54993 | FOXK2 | 3607 | 2 | 5 | 63 | |
| GSE54994 | FOXK2 | 3607 | 10 | 6 | 37 | |
| GSE60625 | FOXK2 | 3607 | 6 | 0 | 5 | |
| GSE74703 | FOXK2 | 3607 | 3 | 3 | 30 | |
| GSE74704 | FOXK2 | 3607 | 4 | 4 | 12 | |
| TCGA | FOXK2 | 3607 | 24 | 14 | 58 |
Total number of gains: 103; Total number of losses: 49; Total Number of normals: 336.
Somatic mutations of FOXK2:
Generating mutation plots.
Highly correlated genes for FOXK2:
Showing top 20/1856 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FOXK2 | ZBTB9 | 0.767473 | 4 | 0 | 4 |
| FOXK2 | IFT80 | 0.760511 | 3 | 0 | 3 |
| FOXK2 | EXOC6 | 0.759517 | 3 | 0 | 3 |
| FOXK2 | NEK3 | 0.756147 | 3 | 0 | 3 |
| FOXK2 | GOPC | 0.753389 | 3 | 0 | 3 |
| FOXK2 | SCAF4 | 0.751443 | 3 | 0 | 3 |
| FOXK2 | TRIM47 | 0.750859 | 3 | 0 | 3 |
| FOXK2 | ZNF628 | 0.750117 | 3 | 0 | 3 |
| FOXK2 | PLEKHA3 | 0.744245 | 3 | 0 | 3 |
| FOXK2 | SRSF10 | 0.743102 | 4 | 0 | 4 |
| FOXK2 | LRRC58 | 0.741656 | 5 | 0 | 5 |
| FOXK2 | RILPL2 | 0.739904 | 3 | 0 | 3 |
| FOXK2 | TET1 | 0.736904 | 3 | 0 | 3 |
| FOXK2 | RNF130 | 0.731847 | 3 | 0 | 3 |
| FOXK2 | PNPT1 | 0.731396 | 5 | 0 | 5 |
| FOXK2 | ANKRD27 | 0.72677 | 3 | 0 | 3 |
| FOXK2 | CDCA2 | 0.725843 | 4 | 0 | 4 |
| FOXK2 | EBNA1BP2 | 0.724797 | 3 | 0 | 3 |
| FOXK2 | FAM89B | 0.724747 | 4 | 0 | 4 |
| FOXK2 | ELOF1 | 0.723741 | 4 | 0 | 4 |
For details and further investigation, click here
