| Full name: cytochrome P450 family 26 subfamily B member 1 | Alias Symbol: P450RAI-2 | ||
| Type: protein-coding gene | Cytoband: 2p13.2 | ||
| Entrez ID: 56603 | HGNC ID: HGNC:20581 | Ensembl Gene: ENSG00000003137 | OMIM ID: 605207 |
| Drug and gene relationship at DGIdb | |||
Expression of CYP26B1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CYP26B1 | 56603 | 219825_at | 1.0602 | 0.4874 | |
| GSE20347 | CYP26B1 | 56603 | 219825_at | 0.1555 | 0.5899 | |
| GSE23400 | CYP26B1 | 56603 | 219825_at | 0.1548 | 0.3874 | |
| GSE26886 | CYP26B1 | 56603 | 219825_at | 0.2497 | 0.5710 | |
| GSE29001 | CYP26B1 | 56603 | 219825_at | 0.1711 | 0.7688 | |
| GSE38129 | CYP26B1 | 56603 | 219825_at | 0.0605 | 0.8223 | |
| GSE45670 | CYP26B1 | 56603 | 219825_at | 0.5361 | 0.3139 | |
| GSE53622 | CYP26B1 | 56603 | 69448 | 0.5882 | 0.0144 | |
| GSE53624 | CYP26B1 | 56603 | 69448 | 0.4007 | 0.0235 | |
| GSE63941 | CYP26B1 | 56603 | 219825_at | -1.8966 | 0.0011 | |
| GSE77861 | CYP26B1 | 56603 | 219825_at | 0.0988 | 0.7343 | |
| GSE97050 | CYP26B1 | 56603 | A_23_P210109 | 0.5408 | 0.2641 | |
| SRP007169 | CYP26B1 | 56603 | RNAseq | 1.0238 | 0.1060 | |
| SRP133303 | CYP26B1 | 56603 | RNAseq | 0.2204 | 0.6277 | |
| SRP159526 | CYP26B1 | 56603 | RNAseq | 1.2521 | 0.0118 | |
| SRP219564 | CYP26B1 | 56603 | RNAseq | 0.9280 | 0.2312 | |
| TCGA | CYP26B1 | 56603 | RNAseq | 0.7249 | 0.0009 |
Upregulated datasets: 1; Downregulated datasets: 1.
Survival by CYP26B1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CYP26B1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CYP26B1 | 56603 | 11 | 1 | 18 | |
| GSE20123 | CYP26B1 | 56603 | 11 | 1 | 18 | |
| GSE43470 | CYP26B1 | 56603 | 3 | 0 | 40 | |
| GSE46452 | CYP26B1 | 56603 | 2 | 3 | 54 | |
| GSE47630 | CYP26B1 | 56603 | 7 | 0 | 33 | |
| GSE54993 | CYP26B1 | 56603 | 0 | 6 | 64 | |
| GSE54994 | CYP26B1 | 56603 | 11 | 0 | 42 | |
| GSE60625 | CYP26B1 | 56603 | 0 | 3 | 8 | |
| GSE74703 | CYP26B1 | 56603 | 3 | 0 | 33 | |
| GSE74704 | CYP26B1 | 56603 | 9 | 0 | 11 | |
| TCGA | CYP26B1 | 56603 | 37 | 2 | 57 |
Total number of gains: 94; Total number of losses: 16; Total Number of normals: 378.
Somatic mutations of CYP26B1:
Generating mutation plots.
Highly correlated genes for CYP26B1:
Showing top 20/219 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CYP26B1 | WDR54 | 0.75198 | 3 | 0 | 3 |
| CYP26B1 | GOPC | 0.749393 | 3 | 0 | 3 |
| CYP26B1 | AHR | 0.739822 | 3 | 0 | 3 |
| CYP26B1 | TACO1 | 0.734296 | 3 | 0 | 3 |
| CYP26B1 | GPR153 | 0.733667 | 3 | 0 | 3 |
| CYP26B1 | SLC15A4 | 0.720712 | 3 | 0 | 3 |
| CYP26B1 | KANK4 | 0.703423 | 4 | 0 | 3 |
| CYP26B1 | ERICH1 | 0.699358 | 4 | 0 | 3 |
| CYP26B1 | NOSIP | 0.689881 | 3 | 0 | 3 |
| CYP26B1 | HCG4 | 0.686039 | 3 | 0 | 3 |
| CYP26B1 | PREP | 0.682763 | 4 | 0 | 3 |
| CYP26B1 | ABHD6 | 0.679218 | 3 | 0 | 3 |
| CYP26B1 | RAB3GAP1 | 0.672629 | 3 | 0 | 3 |
| CYP26B1 | IRF2BPL | 0.671232 | 3 | 0 | 3 |
| CYP26B1 | RAI14 | 0.671201 | 3 | 0 | 3 |
| CYP26B1 | SDF4 | 0.66737 | 3 | 0 | 3 |
| CYP26B1 | KDM1A | 0.664983 | 3 | 0 | 3 |
| CYP26B1 | GNG2 | 0.661436 | 3 | 0 | 3 |
| CYP26B1 | INVS | 0.656944 | 4 | 0 | 3 |
| CYP26B1 | MB21D2 | 0.656939 | 4 | 0 | 3 |
For details and further investigation, click here
