| Full name: filamin A | Alias Symbol: ABP-280 | ||
| Type: protein-coding gene | Cytoband: Xq28 | ||
| Entrez ID: 2316 | HGNC ID: HGNC:3754 | Ensembl Gene: ENSG00000196924 | OMIM ID: 300017 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
FLNA involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04010 | MAPK signaling pathway | |
| hsa04510 | Focal adhesion | |
| hsa05132 | Salmonella infection | |
| hsa05205 | Proteoglycans in cancer |
Expression of FLNA:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FLNA | 2316 | 200859_x_at | -0.6669 | 0.4233 | |
| GSE20347 | FLNA | 2316 | 200859_x_at | 0.8048 | 0.0047 | |
| GSE23400 | FLNA | 2316 | 200859_x_at | -0.1058 | 0.5926 | |
| GSE26886 | FLNA | 2316 | 200859_x_at | 0.9917 | 0.0049 | |
| GSE29001 | FLNA | 2316 | 200859_x_at | 0.3633 | 0.2846 | |
| GSE38129 | FLNA | 2316 | 200859_x_at | 0.1611 | 0.7001 | |
| GSE45670 | FLNA | 2316 | 200859_x_at | -0.5417 | 0.0310 | |
| GSE53622 | FLNA | 2316 | 144858 | -0.5472 | 0.0001 | |
| GSE53624 | FLNA | 2316 | 144858 | 0.0114 | 0.9100 | |
| GSE63941 | FLNA | 2316 | 200859_x_at | 0.2550 | 0.6905 | |
| GSE77861 | FLNA | 2316 | 200859_x_at | 1.0114 | 0.0493 | |
| GSE97050 | FLNA | 2316 | A_33_P3408711 | -1.0453 | 0.1298 | |
| SRP007169 | FLNA | 2316 | RNAseq | 2.4448 | 0.0000 | |
| SRP008496 | FLNA | 2316 | RNAseq | 2.5437 | 0.0000 | |
| SRP064894 | FLNA | 2316 | RNAseq | 0.2542 | 0.4365 | |
| SRP133303 | FLNA | 2316 | RNAseq | 0.3028 | 0.4310 | |
| SRP159526 | FLNA | 2316 | RNAseq | -0.5383 | 0.2733 | |
| SRP193095 | FLNA | 2316 | RNAseq | 1.5694 | 0.0000 | |
| SRP219564 | FLNA | 2316 | RNAseq | -0.8050 | 0.3885 | |
| TCGA | FLNA | 2316 | RNAseq | -0.1063 | 0.1510 |
Upregulated datasets: 4; Downregulated datasets: 0.
Survival by FLNA expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FLNA:
No record found for this gene.
Somatic mutations of FLNA:
Generating mutation plots.
Highly correlated genes for FLNA:
Showing top 20/1029 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FLNA | UBXN10 | 0.849665 | 3 | 0 | 3 |
| FLNA | C20orf194 | 0.831361 | 3 | 0 | 3 |
| FLNA | SORCS1 | 0.820041 | 3 | 0 | 3 |
| FLNA | AKAP6 | 0.817423 | 3 | 0 | 3 |
| FLNA | WSCD2 | 0.816909 | 3 | 0 | 3 |
| FLNA | KCNB1 | 0.809195 | 3 | 0 | 3 |
| FLNA | C9orf47 | 0.799194 | 3 | 0 | 3 |
| FLNA | SMTN | 0.79724 | 11 | 0 | 11 |
| FLNA | CCDC136 | 0.787351 | 3 | 0 | 3 |
| FLNA | ADARB1 | 0.787126 | 7 | 0 | 7 |
| FLNA | PDLIM7 | 0.778848 | 10 | 0 | 10 |
| FLNA | IGIP | 0.777319 | 3 | 0 | 3 |
| FLNA | TGFB1I1 | 0.771635 | 11 | 0 | 11 |
| FLNA | MCAM | 0.768129 | 9 | 0 | 9 |
| FLNA | PALLD | 0.75256 | 9 | 0 | 9 |
| FLNA | LDB3 | 0.750954 | 4 | 0 | 4 |
| FLNA | ZEB1 | 0.748986 | 3 | 0 | 3 |
| FLNA | GLI2 | 0.743776 | 3 | 0 | 3 |
| FLNA | MYLK | 0.742153 | 10 | 0 | 10 |
| FLNA | RASSF3 | 0.741704 | 4 | 0 | 3 |
For details and further investigation, click here
