| Full name: solute carrier family 27 member 4 | Alias Symbol: FATP4|ACSVL4 | ||
| Type: protein-coding gene | Cytoband: 9q34.11 | ||
| Entrez ID: 10999 | HGNC ID: HGNC:10998 | Ensembl Gene: ENSG00000167114 | OMIM ID: 604194 |
| Drug and gene relationship at DGIdb | |||
SLC27A4 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa03320 | PPAR signaling pathway |
Expression of SLC27A4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SLC27A4 | 10999 | 225779_at | -0.3903 | 0.6253 | |
| GSE26886 | SLC27A4 | 10999 | 225779_at | -0.7689 | 0.0012 | |
| GSE45670 | SLC27A4 | 10999 | 225779_at | 0.0799 | 0.6329 | |
| GSE53622 | SLC27A4 | 10999 | 8391 | -0.5312 | 0.0004 | |
| GSE53624 | SLC27A4 | 10999 | 8391 | -0.6420 | 0.0000 | |
| GSE63941 | SLC27A4 | 10999 | 225779_at | 0.3410 | 0.3842 | |
| GSE77861 | SLC27A4 | 10999 | 225779_at | -0.2000 | 0.3518 | |
| GSE97050 | SLC27A4 | 10999 | A_24_P257971 | 0.4930 | 0.2290 | |
| SRP007169 | SLC27A4 | 10999 | RNAseq | -1.1735 | 0.0020 | |
| SRP008496 | SLC27A4 | 10999 | RNAseq | -1.3940 | 0.0000 | |
| SRP064894 | SLC27A4 | 10999 | RNAseq | -0.2431 | 0.3366 | |
| SRP133303 | SLC27A4 | 10999 | RNAseq | -0.7015 | 0.0001 | |
| SRP159526 | SLC27A4 | 10999 | RNAseq | -0.4939 | 0.2065 | |
| SRP193095 | SLC27A4 | 10999 | RNAseq | -0.6281 | 0.0002 | |
| SRP219564 | SLC27A4 | 10999 | RNAseq | -1.0255 | 0.0088 | |
| TCGA | SLC27A4 | 10999 | RNAseq | 0.0984 | 0.2449 |
Upregulated datasets: 0; Downregulated datasets: 3.
Survival by SLC27A4 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SLC27A4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SLC27A4 | 10999 | 6 | 9 | 15 | |
| GSE20123 | SLC27A4 | 10999 | 6 | 9 | 15 | |
| GSE43470 | SLC27A4 | 10999 | 5 | 7 | 31 | |
| GSE46452 | SLC27A4 | 10999 | 6 | 13 | 40 | |
| GSE47630 | SLC27A4 | 10999 | 3 | 16 | 21 | |
| GSE54993 | SLC27A4 | 10999 | 3 | 3 | 64 | |
| GSE54994 | SLC27A4 | 10999 | 11 | 8 | 34 | |
| GSE60625 | SLC27A4 | 10999 | 0 | 0 | 11 | |
| GSE74703 | SLC27A4 | 10999 | 5 | 5 | 26 | |
| GSE74704 | SLC27A4 | 10999 | 3 | 7 | 10 | |
| TCGA | SLC27A4 | 10999 | 27 | 24 | 45 |
Total number of gains: 75; Total number of losses: 101; Total Number of normals: 312.
Somatic mutations of SLC27A4:
Generating mutation plots.
Highly correlated genes for SLC27A4:
Showing top 20/742 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SLC27A4 | PSD4 | 0.726565 | 3 | 0 | 3 |
| SLC27A4 | DUOXA1 | 0.717037 | 7 | 0 | 7 |
| SLC27A4 | LAD1 | 0.712361 | 7 | 0 | 7 |
| SLC27A4 | KRT6C | 0.710214 | 3 | 0 | 3 |
| SLC27A4 | S100A16 | 0.703026 | 7 | 0 | 7 |
| SLC27A4 | BCL10 | 0.69491 | 4 | 0 | 4 |
| SLC27A4 | ULBP2 | 0.69372 | 5 | 0 | 4 |
| SLC27A4 | GJB5 | 0.692707 | 7 | 0 | 7 |
| SLC27A4 | PKP3 | 0.689196 | 7 | 0 | 7 |
| SLC27A4 | EPHA2 | 0.688096 | 6 | 0 | 6 |
| SLC27A4 | ELOVL1 | 0.682596 | 3 | 0 | 3 |
| SLC27A4 | DMKN | 0.682378 | 7 | 0 | 7 |
| SLC27A4 | NSDHL | 0.682054 | 7 | 0 | 7 |
| SLC27A4 | DSG3 | 0.681822 | 7 | 0 | 6 |
| SLC27A4 | ARPC5L | 0.677156 | 7 | 0 | 7 |
| SLC27A4 | ARPC2 | 0.674793 | 5 | 0 | 5 |
| SLC27A4 | EPHA1 | 0.673709 | 7 | 0 | 7 |
| SLC27A4 | C7orf57 | 0.672751 | 5 | 0 | 5 |
| SLC27A4 | KLHL18 | 0.672104 | 4 | 0 | 4 |
| SLC27A4 | FRMD6 | 0.667873 | 3 | 0 | 3 |
For details and further investigation, click here
