| Full name: cytochrome P450 family 2 subfamily S member 1 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 19q13.2 | ||
| Entrez ID: 29785 | HGNC ID: HGNC:15654 | Ensembl Gene: ENSG00000167600 | OMIM ID: 611529 |
| Drug and gene relationship at DGIdb | |||
Expression of CYP2S1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CYP2S1 | 29785 | 223385_at | 0.3482 | 0.8089 | |
| GSE26886 | CYP2S1 | 29785 | 223385_at | 0.3675 | 0.0374 | |
| GSE45670 | CYP2S1 | 29785 | 223385_at | 0.6013 | 0.0069 | |
| GSE53622 | CYP2S1 | 29785 | 20354 | 0.8421 | 0.0010 | |
| GSE53624 | CYP2S1 | 29785 | 20354 | 0.5204 | 0.0003 | |
| GSE63941 | CYP2S1 | 29785 | 223385_at | 1.6129 | 0.0376 | |
| GSE77861 | CYP2S1 | 29785 | 223385_at | 1.6937 | 0.0044 | |
| GSE97050 | CYP2S1 | 29785 | A_33_P3348782 | 2.3942 | 0.0867 | |
| SRP007169 | CYP2S1 | 29785 | RNAseq | 2.4548 | 0.0000 | |
| SRP064894 | CYP2S1 | 29785 | RNAseq | 0.6597 | 0.1592 | |
| SRP133303 | CYP2S1 | 29785 | RNAseq | 1.7390 | 0.0003 | |
| SRP159526 | CYP2S1 | 29785 | RNAseq | 1.6530 | 0.0143 | |
| SRP193095 | CYP2S1 | 29785 | RNAseq | 0.0800 | 0.8421 | |
| SRP219564 | CYP2S1 | 29785 | RNAseq | 1.0209 | 0.2138 | |
| TCGA | CYP2S1 | 29785 | RNAseq | 0.0196 | 0.9097 |
Upregulated datasets: 5; Downregulated datasets: 0.
Survival by CYP2S1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CYP2S1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CYP2S1 | 29785 | 4 | 4 | 22 | |
| GSE20123 | CYP2S1 | 29785 | 4 | 3 | 23 | |
| GSE43470 | CYP2S1 | 29785 | 3 | 11 | 29 | |
| GSE46452 | CYP2S1 | 29785 | 48 | 1 | 10 | |
| GSE47630 | CYP2S1 | 29785 | 9 | 5 | 26 | |
| GSE54993 | CYP2S1 | 29785 | 17 | 4 | 49 | |
| GSE54994 | CYP2S1 | 29785 | 6 | 11 | 36 | |
| GSE60625 | CYP2S1 | 29785 | 9 | 0 | 2 | |
| GSE74703 | CYP2S1 | 29785 | 3 | 7 | 26 | |
| GSE74704 | CYP2S1 | 29785 | 4 | 1 | 15 | |
| TCGA | CYP2S1 | 29785 | 14 | 16 | 66 |
Total number of gains: 121; Total number of losses: 63; Total Number of normals: 304.
Somatic mutations of CYP2S1:
Generating mutation plots.
Highly correlated genes for CYP2S1:
Showing top 20/408 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CYP2S1 | KCNQ5 | 0.732297 | 3 | 0 | 3 |
| CYP2S1 | GPX4 | 0.71848 | 3 | 0 | 3 |
| CYP2S1 | M6PR | 0.699508 | 3 | 0 | 3 |
| CYP2S1 | PUF60 | 0.697809 | 3 | 0 | 3 |
| CYP2S1 | DUS3L | 0.684702 | 4 | 0 | 4 |
| CYP2S1 | C12orf57 | 0.682757 | 3 | 0 | 3 |
| CYP2S1 | GPR137 | 0.678911 | 3 | 0 | 3 |
| CYP2S1 | EHMT1 | 0.676588 | 3 | 0 | 3 |
| CYP2S1 | THAP10 | 0.673042 | 3 | 0 | 3 |
| CYP2S1 | HOGA1 | 0.671632 | 3 | 0 | 3 |
| CYP2S1 | TPM3 | 0.671592 | 3 | 0 | 3 |
| CYP2S1 | AIFM1 | 0.668203 | 3 | 0 | 3 |
| CYP2S1 | SYNGR2 | 0.667706 | 3 | 0 | 3 |
| CYP2S1 | PCBP2 | 0.661289 | 4 | 0 | 3 |
| CYP2S1 | MED30 | 0.660951 | 3 | 0 | 3 |
| CYP2S1 | FXYD3 | 0.660393 | 7 | 0 | 6 |
| CYP2S1 | LDHB | 0.659054 | 3 | 0 | 3 |
| CYP2S1 | LSM4 | 0.658617 | 5 | 0 | 4 |
| CYP2S1 | FARSA | 0.658027 | 4 | 0 | 4 |
| CYP2S1 | WBP11 | 0.656116 | 4 | 0 | 4 |
For details and further investigation, click here
