| Full name: polycomb group ring finger 2 | Alias Symbol: MEL-18 | ||
| Type: protein-coding gene | Cytoband: 17q12 | ||
| Entrez ID: 7703 | HGNC ID: HGNC:12929 | Ensembl Gene: ENSG00000277258 | OMIM ID: 600346 |
| Drug and gene relationship at DGIdb | |||
Expression of PCGF2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PCGF2 | 7703 | 203793_x_at | 0.0191 | 0.9553 | |
| GSE20347 | PCGF2 | 7703 | 203793_x_at | 0.3704 | 0.0022 | |
| GSE23400 | PCGF2 | 7703 | 203793_x_at | 0.1538 | 0.0006 | |
| GSE26886 | PCGF2 | 7703 | 203792_x_at | 0.5324 | 0.0003 | |
| GSE29001 | PCGF2 | 7703 | 203793_x_at | 0.0615 | 0.7085 | |
| GSE38129 | PCGF2 | 7703 | 203793_x_at | 0.1926 | 0.1573 | |
| GSE45670 | PCGF2 | 7703 | 203792_x_at | 0.1654 | 0.1164 | |
| GSE63941 | PCGF2 | 7703 | 203793_x_at | 0.3616 | 0.1744 | |
| GSE77861 | PCGF2 | 7703 | 203792_x_at | 0.1326 | 0.5348 | |
| GSE97050 | PCGF2 | 7703 | A_23_P348323 | -0.0657 | 0.7898 | |
| SRP007169 | PCGF2 | 7703 | RNAseq | 1.0200 | 0.0326 | |
| SRP008496 | PCGF2 | 7703 | RNAseq | 0.7993 | 0.0182 | |
| SRP064894 | PCGF2 | 7703 | RNAseq | 1.2561 | 0.0000 | |
| SRP133303 | PCGF2 | 7703 | RNAseq | 0.4980 | 0.0048 | |
| SRP159526 | PCGF2 | 7703 | RNAseq | 1.0032 | 0.0161 | |
| SRP193095 | PCGF2 | 7703 | RNAseq | 1.1600 | 0.0000 | |
| SRP219564 | PCGF2 | 7703 | RNAseq | 0.8041 | 0.0035 | |
| TCGA | PCGF2 | 7703 | RNAseq | 0.1706 | 0.0050 |
Upregulated datasets: 4; Downregulated datasets: 0.
Survival by PCGF2 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of PCGF2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PCGF2 | 7703 | 7 | 1 | 22 | |
| GSE20123 | PCGF2 | 7703 | 7 | 1 | 22 | |
| GSE43470 | PCGF2 | 7703 | 0 | 1 | 42 | |
| GSE46452 | PCGF2 | 7703 | 34 | 0 | 25 | |
| GSE47630 | PCGF2 | 7703 | 8 | 1 | 31 | |
| GSE54993 | PCGF2 | 7703 | 3 | 4 | 63 | |
| GSE54994 | PCGF2 | 7703 | 8 | 5 | 40 | |
| GSE60625 | PCGF2 | 7703 | 4 | 0 | 7 | |
| GSE74703 | PCGF2 | 7703 | 0 | 0 | 36 | |
| GSE74704 | PCGF2 | 7703 | 4 | 1 | 15 | |
| TCGA | PCGF2 | 7703 | 19 | 9 | 68 |
Total number of gains: 94; Total number of losses: 23; Total Number of normals: 371.
Somatic mutations of PCGF2:
Generating mutation plots.
Highly correlated genes for PCGF2:
Showing top 20/570 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PCGF2 | SLC43A2 | 0.792801 | 3 | 0 | 3 |
| PCGF2 | MAST1 | 0.78674 | 3 | 0 | 3 |
| PCGF2 | NMNAT2 | 0.778926 | 3 | 0 | 3 |
| PCGF2 | VAMP2 | 0.777391 | 3 | 0 | 3 |
| PCGF2 | KRTCAP2 | 0.760549 | 3 | 0 | 3 |
| PCGF2 | RNASEH2C | 0.751436 | 3 | 0 | 3 |
| PCGF2 | PITPNC1 | 0.751045 | 3 | 0 | 3 |
| PCGF2 | CCDC154 | 0.749844 | 3 | 0 | 3 |
| PCGF2 | RILP | 0.745043 | 4 | 0 | 4 |
| PCGF2 | RPTOR | 0.744487 | 3 | 0 | 3 |
| PCGF2 | PTGFRN | 0.741301 | 3 | 0 | 3 |
| PCGF2 | ISCA1 | 0.74071 | 3 | 0 | 3 |
| PCGF2 | RILPL1 | 0.736291 | 3 | 0 | 3 |
| PCGF2 | POLR2J | 0.732028 | 3 | 0 | 3 |
| PCGF2 | TMEM173 | 0.725686 | 3 | 0 | 3 |
| PCGF2 | ACY1 | 0.719951 | 4 | 0 | 3 |
| PCGF2 | RPL38 | 0.719356 | 3 | 0 | 3 |
| PCGF2 | CLDND2 | 0.718401 | 3 | 0 | 3 |
| PCGF2 | SRPK2 | 0.717938 | 3 | 0 | 3 |
| PCGF2 | ACACA | 0.71503 | 3 | 0 | 3 |
For details and further investigation, click here
