| Full name: TRIO and F-actin binding protein | Alias Symbol: HRIHFB2122|KIAA1662|Tara|TAP68 | ||
| Type: protein-coding gene | Cytoband: 22q13.1 | ||
| Entrez ID: 11078 | HGNC ID: HGNC:17009 | Ensembl Gene: ENSG00000100106 | OMIM ID: 609761 |
| Drug and gene relationship at DGIdb | |||
Expression of TRIOBP:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TRIOBP | 11078 | 216210_x_at | -0.7111 | 0.0300 | |
| GSE20347 | TRIOBP | 11078 | 216210_x_at | -0.8543 | 0.0000 | |
| GSE23400 | TRIOBP | 11078 | 216210_x_at | -0.6710 | 0.0000 | |
| GSE26886 | TRIOBP | 11078 | 216210_x_at | 0.1358 | 0.5559 | |
| GSE29001 | TRIOBP | 11078 | 202795_x_at | -0.7488 | 0.0091 | |
| GSE38129 | TRIOBP | 11078 | 216210_x_at | -0.8692 | 0.0000 | |
| GSE45670 | TRIOBP | 11078 | 216210_x_at | -0.6963 | 0.0001 | |
| GSE53622 | TRIOBP | 11078 | 154688 | -1.5790 | 0.0000 | |
| GSE53624 | TRIOBP | 11078 | 12302 | -0.6930 | 0.0000 | |
| GSE63941 | TRIOBP | 11078 | 216210_x_at | -0.6167 | 0.2268 | |
| GSE77861 | TRIOBP | 11078 | 216210_x_at | -0.3331 | 0.0290 | |
| GSE97050 | TRIOBP | 11078 | A_23_P17855 | -1.0632 | 0.0620 | |
| SRP007169 | TRIOBP | 11078 | RNAseq | -1.3874 | 0.0001 | |
| SRP008496 | TRIOBP | 11078 | RNAseq | -1.3447 | 0.0000 | |
| SRP064894 | TRIOBP | 11078 | RNAseq | -0.5286 | 0.0006 | |
| SRP133303 | TRIOBP | 11078 | RNAseq | -1.0429 | 0.0000 | |
| SRP159526 | TRIOBP | 11078 | RNAseq | -0.7668 | 0.0036 | |
| SRP193095 | TRIOBP | 11078 | RNAseq | -0.7210 | 0.0000 | |
| SRP219564 | TRIOBP | 11078 | RNAseq | -0.8134 | 0.0069 | |
| TCGA | TRIOBP | 11078 | RNAseq | -0.1980 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 4.
Survival by TRIOBP expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TRIOBP:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TRIOBP | 11078 | 6 | 5 | 19 | |
| GSE20123 | TRIOBP | 11078 | 6 | 4 | 20 | |
| GSE43470 | TRIOBP | 11078 | 4 | 6 | 33 | |
| GSE46452 | TRIOBP | 11078 | 32 | 2 | 25 | |
| GSE47630 | TRIOBP | 11078 | 9 | 4 | 27 | |
| GSE54993 | TRIOBP | 11078 | 3 | 6 | 61 | |
| GSE54994 | TRIOBP | 11078 | 9 | 8 | 36 | |
| GSE60625 | TRIOBP | 11078 | 5 | 0 | 6 | |
| GSE74703 | TRIOBP | 11078 | 4 | 4 | 28 | |
| GSE74704 | TRIOBP | 11078 | 3 | 2 | 15 | |
| TCGA | TRIOBP | 11078 | 27 | 15 | 54 |
Total number of gains: 108; Total number of losses: 56; Total Number of normals: 324.
Somatic mutations of TRIOBP:
Generating mutation plots.
Highly correlated genes for TRIOBP:
Showing top 20/1282 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TRIOBP | SNX9 | 0.768315 | 5 | 0 | 5 |
| TRIOBP | FAM219B | 0.765016 | 3 | 0 | 3 |
| TRIOBP | SFTA2 | 0.736324 | 3 | 0 | 3 |
| TRIOBP | CGNL1 | 0.730231 | 5 | 0 | 5 |
| TRIOBP | FAM95B1 | 0.725237 | 3 | 0 | 3 |
| TRIOBP | RAB9B | 0.725168 | 4 | 0 | 4 |
| TRIOBP | NDRG2 | 0.721866 | 7 | 0 | 7 |
| TRIOBP | BOC | 0.717677 | 5 | 0 | 5 |
| TRIOBP | ZNF662 | 0.716777 | 5 | 0 | 5 |
| TRIOBP | PADI1 | 0.716402 | 7 | 0 | 7 |
| TRIOBP | SECISBP2L | 0.713684 | 9 | 0 | 9 |
| TRIOBP | GAB2 | 0.71361 | 8 | 0 | 8 |
| TRIOBP | SORT1 | 0.711264 | 10 | 0 | 9 |
| TRIOBP | TJP3 | 0.71012 | 7 | 0 | 7 |
| TRIOBP | HPGD | 0.708466 | 10 | 0 | 9 |
| TRIOBP | HDHD2 | 0.707368 | 3 | 0 | 3 |
| TRIOBP | NFIA | 0.707138 | 5 | 0 | 5 |
| TRIOBP | SNORA68 | 0.706857 | 3 | 0 | 3 |
| TRIOBP | CNPPD1 | 0.704093 | 8 | 0 | 8 |
| TRIOBP | USP54 | 0.700506 | 5 | 0 | 5 |
For details and further investigation, click here
