| Full name: NCK interacting protein with SH3 domain | Alias Symbol: AF3P21|SPIN90|ORF1|WISH|WASLBP|DIP1 | ||
| Type: protein-coding gene | Cytoband: 3p21.31 | ||
| Entrez ID: 51517 | HGNC ID: HGNC:15486 | Ensembl Gene: ENSG00000213672 | OMIM ID: 606671 |
| Drug and gene relationship at DGIdb | |||
Expression of NCKIPSD:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NCKIPSD | 51517 | 218697_at | 0.1215 | 0.6984 | |
| GSE20347 | NCKIPSD | 51517 | 216114_at | 0.0676 | 0.5819 | |
| GSE23400 | NCKIPSD | 51517 | 218697_at | 0.2555 | 0.0000 | |
| GSE26886 | NCKIPSD | 51517 | 218697_at | 0.6069 | 0.0025 | |
| GSE29001 | NCKIPSD | 51517 | 218697_at | 0.2436 | 0.3330 | |
| GSE38129 | NCKIPSD | 51517 | 218697_at | 0.1213 | 0.2954 | |
| GSE45670 | NCKIPSD | 51517 | 218697_at | 0.0398 | 0.7432 | |
| GSE53622 | NCKIPSD | 51517 | 152671 | 0.0447 | 0.6065 | |
| GSE53624 | NCKIPSD | 51517 | 90863 | 0.0235 | 0.7335 | |
| GSE63941 | NCKIPSD | 51517 | 218697_at | 0.2084 | 0.6176 | |
| GSE77861 | NCKIPSD | 51517 | 218697_at | 0.1415 | 0.5808 | |
| GSE97050 | NCKIPSD | 51517 | A_33_P3288023 | 0.0011 | 0.9975 | |
| SRP007169 | NCKIPSD | 51517 | RNAseq | -0.1284 | 0.7922 | |
| SRP008496 | NCKIPSD | 51517 | RNAseq | -0.0385 | 0.9090 | |
| SRP064894 | NCKIPSD | 51517 | RNAseq | 0.6038 | 0.0008 | |
| SRP133303 | NCKIPSD | 51517 | RNAseq | -0.1173 | 0.3794 | |
| SRP159526 | NCKIPSD | 51517 | RNAseq | 0.3011 | 0.2456 | |
| SRP193095 | NCKIPSD | 51517 | RNAseq | 0.1184 | 0.2950 | |
| SRP219564 | NCKIPSD | 51517 | RNAseq | 0.2387 | 0.5853 | |
| TCGA | NCKIPSD | 51517 | RNAseq | -0.0873 | 0.1036 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by NCKIPSD expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NCKIPSD:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NCKIPSD | 51517 | 0 | 18 | 12 | |
| GSE20123 | NCKIPSD | 51517 | 0 | 19 | 11 | |
| GSE43470 | NCKIPSD | 51517 | 0 | 19 | 24 | |
| GSE46452 | NCKIPSD | 51517 | 3 | 16 | 40 | |
| GSE47630 | NCKIPSD | 51517 | 1 | 24 | 15 | |
| GSE54993 | NCKIPSD | 51517 | 6 | 2 | 62 | |
| GSE54994 | NCKIPSD | 51517 | 0 | 37 | 16 | |
| GSE60625 | NCKIPSD | 51517 | 5 | 0 | 6 | |
| GSE74703 | NCKIPSD | 51517 | 0 | 15 | 21 | |
| GSE74704 | NCKIPSD | 51517 | 0 | 12 | 8 | |
| TCGA | NCKIPSD | 51517 | 0 | 78 | 18 |
Total number of gains: 15; Total number of losses: 240; Total Number of normals: 233.
Somatic mutations of NCKIPSD:
Generating mutation plots.
Highly correlated genes for NCKIPSD:
Showing top 20/412 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NCKIPSD | LENG8 | 0.775923 | 3 | 0 | 3 |
| NCKIPSD | SP100 | 0.767502 | 3 | 0 | 3 |
| NCKIPSD | SFR1 | 0.748317 | 3 | 0 | 3 |
| NCKIPSD | CDC42EP4 | 0.743602 | 3 | 0 | 3 |
| NCKIPSD | ITGA8 | 0.740181 | 3 | 0 | 3 |
| NCKIPSD | ASB2 | 0.738018 | 3 | 0 | 3 |
| NCKIPSD | GXYLT2 | 0.730652 | 3 | 0 | 3 |
| NCKIPSD | BBX | 0.728541 | 3 | 0 | 3 |
| NCKIPSD | SLC41A2 | 0.726539 | 3 | 0 | 3 |
| NCKIPSD | SH2B1 | 0.723936 | 3 | 0 | 3 |
| NCKIPSD | TTYH2 | 0.722234 | 3 | 0 | 3 |
| NCKIPSD | DGKD | 0.718276 | 3 | 0 | 3 |
| NCKIPSD | NEK6 | 0.716183 | 3 | 0 | 3 |
| NCKIPSD | WTIP | 0.714423 | 4 | 0 | 4 |
| NCKIPSD | ZNF827 | 0.714338 | 4 | 0 | 3 |
| NCKIPSD | BBS1 | 0.713049 | 3 | 0 | 3 |
| NCKIPSD | UTP23 | 0.712309 | 3 | 0 | 3 |
| NCKIPSD | LARS2 | 0.709708 | 3 | 0 | 3 |
| NCKIPSD | ZNF579 | 0.709077 | 3 | 0 | 3 |
| NCKIPSD | SH3KBP1 | 0.706746 | 3 | 0 | 3 |
For details and further investigation, click here
