| Full name: cyclase associated actin cytoskeleton regulatory protein 2 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 6p22.3 | ||
| Entrez ID: 10486 | HGNC ID: HGNC:20039 | Ensembl Gene: ENSG00000112186 | OMIM ID: 618385 |
| Drug and gene relationship at DGIdb | |||
Expression of CAP2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CAP2 | 10486 | 212551_at | -1.0595 | 0.2936 | |
| GSE20347 | CAP2 | 10486 | 212551_at | -0.4305 | 0.1386 | |
| GSE23400 | CAP2 | 10486 | 212551_at | -0.3822 | 0.0058 | |
| GSE26886 | CAP2 | 10486 | 212554_at | -0.1110 | 0.6962 | |
| GSE29001 | CAP2 | 10486 | 212554_at | -0.6100 | 0.0963 | |
| GSE38129 | CAP2 | 10486 | 212551_at | -0.9426 | 0.0027 | |
| GSE45670 | CAP2 | 10486 | 212554_at | -1.3271 | 0.0001 | |
| GSE53622 | CAP2 | 10486 | 69368 | -1.0938 | 0.0000 | |
| GSE53624 | CAP2 | 10486 | 69368 | -0.8205 | 0.0000 | |
| GSE63941 | CAP2 | 10486 | 212551_at | -0.7565 | 0.2933 | |
| GSE77861 | CAP2 | 10486 | 212551_at | 0.0408 | 0.8970 | |
| GSE97050 | CAP2 | 10486 | A_33_P3739260 | -1.3899 | 0.0981 | |
| SRP007169 | CAP2 | 10486 | RNAseq | -1.1610 | 0.0400 | |
| SRP008496 | CAP2 | 10486 | RNAseq | -0.7890 | 0.0363 | |
| SRP064894 | CAP2 | 10486 | RNAseq | -0.3562 | 0.2346 | |
| SRP133303 | CAP2 | 10486 | RNAseq | -0.3992 | 0.2719 | |
| SRP159526 | CAP2 | 10486 | RNAseq | -0.9948 | 0.0099 | |
| SRP193095 | CAP2 | 10486 | RNAseq | 0.0459 | 0.8321 | |
| SRP219564 | CAP2 | 10486 | RNAseq | -0.8667 | 0.3567 | |
| TCGA | CAP2 | 10486 | RNAseq | -0.0589 | 0.7124 |
Upregulated datasets: 0; Downregulated datasets: 3.
Survival by CAP2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CAP2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CAP2 | 10486 | 3 | 5 | 22 | |
| GSE20123 | CAP2 | 10486 | 3 | 5 | 22 | |
| GSE43470 | CAP2 | 10486 | 9 | 0 | 34 | |
| GSE46452 | CAP2 | 10486 | 1 | 10 | 48 | |
| GSE47630 | CAP2 | 10486 | 7 | 7 | 26 | |
| GSE54993 | CAP2 | 10486 | 1 | 1 | 68 | |
| GSE54994 | CAP2 | 10486 | 10 | 3 | 40 | |
| GSE60625 | CAP2 | 10486 | 0 | 1 | 10 | |
| GSE74703 | CAP2 | 10486 | 8 | 0 | 28 | |
| GSE74704 | CAP2 | 10486 | 2 | 2 | 16 | |
| TCGA | CAP2 | 10486 | 16 | 26 | 54 |
Total number of gains: 60; Total number of losses: 60; Total Number of normals: 368.
Somatic mutations of CAP2:
Generating mutation plots.
Highly correlated genes for CAP2:
Showing top 20/480 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CAP2 | KBTBD12 | 0.753843 | 3 | 0 | 3 |
| CAP2 | BTD | 0.723691 | 3 | 0 | 3 |
| CAP2 | PPP1R12C | 0.717688 | 3 | 0 | 3 |
| CAP2 | C8orf88 | 0.715095 | 3 | 0 | 3 |
| CAP2 | GKAP1 | 0.713108 | 3 | 0 | 3 |
| CAP2 | ALDH1A2 | 0.691058 | 3 | 0 | 3 |
| CAP2 | MYOM1 | 0.690846 | 8 | 0 | 7 |
| CAP2 | RASSF3 | 0.68634 | 4 | 0 | 4 |
| CAP2 | SLC8A1 | 0.683456 | 5 | 0 | 4 |
| CAP2 | DUSP3 | 0.680397 | 7 | 0 | 6 |
| CAP2 | GRIN2A | 0.676894 | 3 | 0 | 3 |
| CAP2 | SMTN | 0.6762 | 7 | 0 | 6 |
| CAP2 | SLC12A2 | 0.675822 | 3 | 0 | 3 |
| CAP2 | TMEM74 | 0.675572 | 3 | 0 | 3 |
| CAP2 | PDZD4 | 0.672922 | 4 | 0 | 3 |
| CAP2 | HECTD2 | 0.672706 | 5 | 0 | 4 |
| CAP2 | RBM24 | 0.66997 | 6 | 0 | 6 |
| CAP2 | LRCH2 | 0.669512 | 4 | 0 | 3 |
| CAP2 | ACTN2 | 0.667621 | 5 | 0 | 4 |
| CAP2 | MORN5 | 0.666758 | 3 | 0 | 3 |
For details and further investigation, click here
