| Full name: glutathione S-transferase pi 1 | Alias Symbol: GSTP | ||
| Type: protein-coding gene | Cytoband: 11q13.2 | ||
| Entrez ID: 2950 | HGNC ID: HGNC:4638 | Ensembl Gene: ENSG00000084207 | OMIM ID: 134660 |
| Drug and gene relationship at DGIdb | |||
GSTP1 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa05215 | Prostate cancer |
Expression of GSTP1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GSTP1 | 2950 | 200824_at | -0.0234 | 0.9796 | |
| GSE20347 | GSTP1 | 2950 | 200824_at | -0.2098 | 0.2682 | |
| GSE23400 | GSTP1 | 2950 | 200824_at | -0.1085 | 0.3714 | |
| GSE26886 | GSTP1 | 2950 | 200824_at | 0.0027 | 0.9946 | |
| GSE29001 | GSTP1 | 2950 | 200824_at | -0.9073 | 0.0229 | |
| GSE38129 | GSTP1 | 2950 | 200824_at | 0.2218 | 0.3905 | |
| GSE45670 | GSTP1 | 2950 | 200824_at | 0.0905 | 0.5287 | |
| GSE53622 | GSTP1 | 2950 | 3960 | -0.3106 | 0.0096 | |
| GSE53624 | GSTP1 | 2950 | 3960 | -0.0854 | 0.2568 | |
| GSE63941 | GSTP1 | 2950 | 200824_at | 1.7039 | 0.0030 | |
| GSE77861 | GSTP1 | 2950 | 200824_at | -0.0041 | 0.9865 | |
| GSE97050 | GSTP1 | 2950 | A_23_P202658 | -0.0569 | 0.9022 | |
| SRP007169 | GSTP1 | 2950 | RNAseq | -1.3920 | 0.0001 | |
| SRP008496 | GSTP1 | 2950 | RNAseq | -1.2606 | 0.0000 | |
| SRP064894 | GSTP1 | 2950 | RNAseq | -0.4284 | 0.2024 | |
| SRP133303 | GSTP1 | 2950 | RNAseq | -0.2461 | 0.1862 | |
| SRP159526 | GSTP1 | 2950 | RNAseq | -0.5154 | 0.1152 | |
| SRP193095 | GSTP1 | 2950 | RNAseq | -0.2643 | 0.2529 | |
| SRP219564 | GSTP1 | 2950 | RNAseq | -0.2072 | 0.7266 | |
| TCGA | GSTP1 | 2950 | RNAseq | 0.3758 | 0.0000 |
Upregulated datasets: 1; Downregulated datasets: 2.
Survival by GSTP1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GSTP1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GSTP1 | 2950 | 10 | 3 | 17 | |
| GSE20123 | GSTP1 | 2950 | 10 | 3 | 17 | |
| GSE43470 | GSTP1 | 2950 | 5 | 2 | 36 | |
| GSE46452 | GSTP1 | 2950 | 14 | 3 | 42 | |
| GSE47630 | GSTP1 | 2950 | 8 | 5 | 27 | |
| GSE54993 | GSTP1 | 2950 | 3 | 1 | 66 | |
| GSE54994 | GSTP1 | 2950 | 13 | 4 | 36 | |
| GSE60625 | GSTP1 | 2950 | 0 | 3 | 8 | |
| GSE74703 | GSTP1 | 2950 | 4 | 1 | 31 | |
| GSE74704 | GSTP1 | 2950 | 8 | 1 | 11 | |
| TCGA | GSTP1 | 2950 | 36 | 9 | 51 |
Total number of gains: 111; Total number of losses: 35; Total Number of normals: 342.
Somatic mutations of GSTP1:
Generating mutation plots.
Highly correlated genes for GSTP1:
Showing top 20/468 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GSTP1 | GRHL2 | 0.719463 | 4 | 0 | 4 |
| GSTP1 | KLF5 | 0.71642 | 7 | 0 | 6 |
| GSTP1 | TSEN54 | 0.714413 | 3 | 0 | 3 |
| GSTP1 | USP43 | 0.711365 | 3 | 0 | 3 |
| GSTP1 | RPS14 | 0.707405 | 3 | 0 | 3 |
| GSTP1 | AP1S3 | 0.707019 | 3 | 0 | 3 |
| GSTP1 | SORD | 0.698799 | 4 | 0 | 4 |
| GSTP1 | LPAR5 | 0.69295 | 5 | 0 | 4 |
| GSTP1 | C6orf132 | 0.691773 | 4 | 0 | 4 |
| GSTP1 | KCTD1 | 0.689039 | 3 | 0 | 3 |
| GSTP1 | PRDX1 | 0.675391 | 8 | 0 | 6 |
| GSTP1 | SERPINB5 | 0.674583 | 8 | 0 | 6 |
| GSTP1 | KDF1 | 0.669118 | 4 | 0 | 4 |
| GSTP1 | S100A2 | 0.668432 | 9 | 0 | 7 |
| GSTP1 | STAP2 | 0.665644 | 6 | 0 | 5 |
| GSTP1 | SDC1 | 0.662825 | 10 | 0 | 9 |
| GSTP1 | PPP1CA | 0.660449 | 12 | 0 | 10 |
| GSTP1 | ARHGAP5-AS1 | 0.65918 | 3 | 0 | 3 |
| GSTP1 | COQ2 | 0.655821 | 4 | 0 | 4 |
| GSTP1 | CEP76 | 0.650245 | 4 | 0 | 3 |
For details and further investigation, click here
