| Full name: potassium channel tetramerization domain containing 1 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 18q11.2 | ||
| Entrez ID: 284252 | HGNC ID: HGNC:18249 | Ensembl Gene: ENSG00000134504 | OMIM ID: 613420 |
| Drug and gene relationship at DGIdb | |||
Expression of KCTD1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | KCTD1 | 284252 | 226246_at | -0.1947 | 0.7413 | |
| GSE26886 | KCTD1 | 284252 | 226245_at | -0.3258 | 0.0512 | |
| GSE45670 | KCTD1 | 284252 | 226245_at | -0.0799 | 0.7395 | |
| GSE53622 | KCTD1 | 284252 | 97494 | -0.2668 | 0.0527 | |
| GSE53624 | KCTD1 | 284252 | 97494 | -0.3470 | 0.0000 | |
| GSE63941 | KCTD1 | 284252 | 226246_at | 1.7053 | 0.0066 | |
| GSE77861 | KCTD1 | 284252 | 226245_at | -0.0412 | 0.9327 | |
| GSE97050 | KCTD1 | 284252 | A_23_P130343 | -0.0150 | 0.9653 | |
| SRP007169 | KCTD1 | 284252 | RNAseq | -0.5975 | 0.1856 | |
| SRP008496 | KCTD1 | 284252 | RNAseq | -0.8423 | 0.0123 | |
| SRP064894 | KCTD1 | 284252 | RNAseq | -1.0069 | 0.0000 | |
| SRP133303 | KCTD1 | 284252 | RNAseq | -0.4871 | 0.0831 | |
| SRP159526 | KCTD1 | 284252 | RNAseq | -0.3048 | 0.3218 | |
| SRP193095 | KCTD1 | 284252 | RNAseq | -0.6941 | 0.0060 | |
| SRP219564 | KCTD1 | 284252 | RNAseq | -0.8217 | 0.1290 | |
| TCGA | KCTD1 | 284252 | RNAseq | 0.3692 | 0.0000 |
Upregulated datasets: 1; Downregulated datasets: 1.
Survival by KCTD1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of KCTD1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | KCTD1 | 284252 | 2 | 5 | 23 | |
| GSE20123 | KCTD1 | 284252 | 2 | 5 | 23 | |
| GSE43470 | KCTD1 | 284252 | 0 | 2 | 41 | |
| GSE46452 | KCTD1 | 284252 | 1 | 25 | 33 | |
| GSE47630 | KCTD1 | 284252 | 6 | 19 | 15 | |
| GSE54993 | KCTD1 | 284252 | 7 | 1 | 62 | |
| GSE54994 | KCTD1 | 284252 | 3 | 14 | 36 | |
| GSE60625 | KCTD1 | 284252 | 0 | 4 | 7 | |
| GSE74703 | KCTD1 | 284252 | 0 | 2 | 34 | |
| GSE74704 | KCTD1 | 284252 | 1 | 4 | 15 | |
| TCGA | KCTD1 | 284252 | 15 | 33 | 48 |
Total number of gains: 37; Total number of losses: 114; Total Number of normals: 337.
Somatic mutations of KCTD1:
Generating mutation plots.
Highly correlated genes for KCTD1:
Showing top 20/310 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| KCTD1 | RRNAD1 | 0.746442 | 3 | 0 | 3 |
| KCTD1 | SSBP1 | 0.727291 | 3 | 0 | 3 |
| KCTD1 | IRX3 | 0.727044 | 3 | 0 | 3 |
| KCTD1 | TUBB4B | 0.715938 | 3 | 0 | 3 |
| KCTD1 | MRPS30 | 0.711025 | 3 | 0 | 3 |
| KCTD1 | SORD | 0.706586 | 3 | 0 | 3 |
| KCTD1 | TYSND1 | 0.706276 | 4 | 0 | 3 |
| KCTD1 | PLEKHH1 | 0.705737 | 3 | 0 | 3 |
| KCTD1 | UPF3B | 0.704983 | 3 | 0 | 3 |
| KCTD1 | RWDD2B | 0.698017 | 3 | 0 | 3 |
| KCTD1 | MBD2 | 0.696959 | 4 | 0 | 4 |
| KCTD1 | GSTP1 | 0.689039 | 3 | 0 | 3 |
| KCTD1 | NOP10 | 0.687226 | 3 | 0 | 3 |
| KCTD1 | PIGF | 0.679063 | 3 | 0 | 3 |
| KCTD1 | CERS3 | 0.677797 | 4 | 0 | 4 |
| KCTD1 | RPAP1 | 0.673663 | 3 | 0 | 3 |
| KCTD1 | PPP1CC | 0.672547 | 3 | 0 | 3 |
| KCTD1 | GTF2A1 | 0.6725 | 3 | 0 | 3 |
| KCTD1 | MBNL3 | 0.671522 | 3 | 0 | 3 |
| KCTD1 | SEMA4A | 0.671135 | 5 | 0 | 5 |
For details and further investigation, click here
