| Full name: ubiquitin specific peptidase 43 | Alias Symbol: FLJ30626 | ||
| Type: protein-coding gene | Cytoband: 17p12 | ||
| Entrez ID: 124739 | HGNC ID: HGNC:20072 | Ensembl Gene: ENSG00000154914 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of USP43:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | USP43 | 124739 | 237439_at | -0.0890 | 0.9215 | |
| GSE26886 | USP43 | 124739 | 237439_at | -0.4346 | 0.0914 | |
| GSE45670 | USP43 | 124739 | 237439_at | 0.1856 | 0.3277 | |
| GSE53622 | USP43 | 124739 | 27527 | -0.5282 | 0.0691 | |
| GSE53624 | USP43 | 124739 | 27527 | -0.7418 | 0.0000 | |
| GSE63941 | USP43 | 124739 | 237439_at | 0.8085 | 0.0261 | |
| GSE77861 | USP43 | 124739 | 237439_at | -0.0431 | 0.8446 | |
| SRP007169 | USP43 | 124739 | RNAseq | -0.8316 | 0.1530 | |
| SRP064894 | USP43 | 124739 | RNAseq | -0.3948 | 0.2865 | |
| SRP133303 | USP43 | 124739 | RNAseq | -0.3462 | 0.1341 | |
| SRP159526 | USP43 | 124739 | RNAseq | -0.9254 | 0.0285 | |
| SRP193095 | USP43 | 124739 | RNAseq | 0.0469 | 0.7822 | |
| SRP219564 | USP43 | 124739 | RNAseq | -0.0034 | 0.9974 | |
| TCGA | USP43 | 124739 | RNAseq | 0.3491 | 0.0219 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by USP43 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of USP43:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | USP43 | 124739 | 3 | 3 | 24 | |
| GSE20123 | USP43 | 124739 | 3 | 4 | 23 | |
| GSE43470 | USP43 | 124739 | 2 | 6 | 35 | |
| GSE46452 | USP43 | 124739 | 34 | 1 | 24 | |
| GSE47630 | USP43 | 124739 | 7 | 1 | 32 | |
| GSE54993 | USP43 | 124739 | 4 | 3 | 63 | |
| GSE54994 | USP43 | 124739 | 5 | 8 | 40 | |
| GSE60625 | USP43 | 124739 | 4 | 0 | 7 | |
| GSE74703 | USP43 | 124739 | 2 | 4 | 30 | |
| GSE74704 | USP43 | 124739 | 1 | 2 | 17 | |
| TCGA | USP43 | 124739 | 17 | 20 | 59 |
Total number of gains: 82; Total number of losses: 52; Total Number of normals: 354.
Somatic mutations of USP43:
Generating mutation plots.
Highly correlated genes for USP43:
Showing top 20/345 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| USP43 | GSTP1 | 0.711365 | 3 | 0 | 3 |
| USP43 | TRIM7 | 0.694562 | 5 | 0 | 5 |
| USP43 | C1orf116 | 0.694077 | 4 | 0 | 4 |
| USP43 | N4BP1 | 0.687133 | 3 | 0 | 3 |
| USP43 | SAMD9 | 0.678652 | 5 | 0 | 5 |
| USP43 | GNA15 | 0.675813 | 7 | 0 | 7 |
| USP43 | PPP4C | 0.665845 | 4 | 0 | 4 |
| USP43 | IL1A | 0.665595 | 6 | 0 | 6 |
| USP43 | RPE | 0.665203 | 3 | 0 | 3 |
| USP43 | RHOD | 0.662358 | 5 | 0 | 5 |
| USP43 | SLC22A18 | 0.659491 | 3 | 0 | 3 |
| USP43 | CDS1 | 0.659283 | 5 | 0 | 4 |
| USP43 | TMEM41B | 0.654323 | 3 | 0 | 3 |
| USP43 | MREG | 0.653834 | 5 | 0 | 3 |
| USP43 | SH3D21 | 0.653455 | 3 | 0 | 3 |
| USP43 | SERPINB5 | 0.649233 | 6 | 0 | 6 |
| USP43 | SPAG1 | 0.64888 | 3 | 0 | 3 |
| USP43 | SFN | 0.647573 | 6 | 0 | 5 |
| USP43 | EPHA1 | 0.647134 | 4 | 0 | 3 |
| USP43 | RDH13 | 0.644915 | 3 | 0 | 3 |
For details and further investigation, click here
