| Full name: GS homeobox 2 | Alias Symbol: Gsh2 | ||
| Type: protein-coding gene | Cytoband: 4q12 | ||
| Entrez ID: 170825 | HGNC ID: HGNC:24959 | Ensembl Gene: ENSG00000180613 | OMIM ID: 616253 |
| Drug and gene relationship at DGIdb | |||
Expression of GSX2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GSX2 | 170825 | 230338_x_at | 0.0662 | 0.8420 | |
| GSE26886 | GSX2 | 170825 | 230338_x_at | -0.2487 | 0.0344 | |
| GSE45670 | GSX2 | 170825 | 230338_x_at | -0.1227 | 0.1758 | |
| GSE53622 | GSX2 | 170825 | 92010 | 0.0347 | 0.8379 | |
| GSE53624 | GSX2 | 170825 | 92010 | -0.0942 | 0.2741 | |
| GSE63941 | GSX2 | 170825 | 230338_x_at | 0.3931 | 0.0247 | |
| GSE77861 | GSX2 | 170825 | 230338_x_at | -0.1376 | 0.3589 | |
| GSE97050 | GSX2 | 170825 | A_23_P92453 | -0.1255 | 0.8581 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by GSX2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GSX2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GSX2 | 170825 | 3 | 11 | 16 | |
| GSE20123 | GSX2 | 170825 | 2 | 11 | 17 | |
| GSE43470 | GSX2 | 170825 | 0 | 14 | 29 | |
| GSE46452 | GSX2 | 170825 | 1 | 36 | 22 | |
| GSE47630 | GSX2 | 170825 | 1 | 18 | 21 | |
| GSE54993 | GSX2 | 170825 | 7 | 0 | 63 | |
| GSE54994 | GSX2 | 170825 | 2 | 10 | 41 | |
| GSE60625 | GSX2 | 170825 | 0 | 0 | 11 | |
| GSE74703 | GSX2 | 170825 | 0 | 12 | 24 | |
| GSE74704 | GSX2 | 170825 | 1 | 6 | 13 | |
| TCGA | GSX2 | 170825 | 18 | 26 | 52 |
Total number of gains: 35; Total number of losses: 144; Total Number of normals: 309.
Somatic mutations of GSX2:
Generating mutation plots.
Highly correlated genes for GSX2:
Showing top 20/216 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GSX2 | MAPK11 | 0.713341 | 3 | 0 | 3 |
| GSX2 | PRELID1 | 0.704802 | 4 | 0 | 4 |
| GSX2 | ZNF467 | 0.688171 | 3 | 0 | 3 |
| GSX2 | ARF3 | 0.682206 | 3 | 0 | 3 |
| GSX2 | IL27 | 0.680554 | 3 | 0 | 3 |
| GSX2 | AKT1S1 | 0.679496 | 3 | 0 | 3 |
| GSX2 | AKIRIN2 | 0.677425 | 3 | 0 | 3 |
| GSX2 | PSKH1 | 0.654989 | 3 | 0 | 3 |
| GSX2 | NFKBID | 0.654489 | 3 | 0 | 3 |
| GSX2 | ACTL7B | 0.65261 | 4 | 0 | 3 |
| GSX2 | SH3BP1 | 0.650996 | 3 | 0 | 3 |
| GSX2 | KCNG2 | 0.647678 | 3 | 0 | 3 |
| GSX2 | CNOT1 | 0.64429 | 3 | 0 | 3 |
| GSX2 | SEMA4A | 0.643275 | 4 | 0 | 4 |
| GSX2 | AKAP14 | 0.642644 | 3 | 0 | 3 |
| GSX2 | ROBO4 | 0.64234 | 3 | 0 | 3 |
| GSX2 | PMVK | 0.639806 | 3 | 0 | 3 |
| GSX2 | OLFM2 | 0.638825 | 3 | 0 | 3 |
| GSX2 | NR1H2 | 0.638142 | 3 | 0 | 3 |
| GSX2 | NLGN3 | 0.637131 | 3 | 0 | 3 |
For details and further investigation, click here
