| Full name: NHS like 1 | Alias Symbol: bA43P8.1|KIAA1357 | ||
| Type: protein-coding gene | Cytoband: 6q24.1 | ||
| Entrez ID: 57224 | HGNC ID: HGNC:21021 | Ensembl Gene: ENSG00000135540 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of NHSL1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NHSL1 | 57224 | 226490_at | -0.1157 | 0.9144 | |
| GSE26886 | NHSL1 | 57224 | 226490_at | -0.3805 | 0.3620 | |
| GSE45670 | NHSL1 | 57224 | 226490_at | -0.2494 | 0.1317 | |
| GSE53622 | NHSL1 | 57224 | 91634 | -0.4241 | 0.0002 | |
| GSE53624 | NHSL1 | 57224 | 91634 | -0.6597 | 0.0000 | |
| GSE63941 | NHSL1 | 57224 | 226490_at | -0.1156 | 0.9011 | |
| GSE77861 | NHSL1 | 57224 | 226490_at | -0.0986 | 0.7110 | |
| GSE97050 | NHSL1 | 57224 | A_23_P387184 | 0.1907 | 0.7838 | |
| SRP007169 | NHSL1 | 57224 | RNAseq | -0.4255 | 0.2101 | |
| SRP008496 | NHSL1 | 57224 | RNAseq | -0.6641 | 0.0048 | |
| SRP064894 | NHSL1 | 57224 | RNAseq | -0.6832 | 0.0021 | |
| SRP133303 | NHSL1 | 57224 | RNAseq | -0.4850 | 0.0331 | |
| SRP159526 | NHSL1 | 57224 | RNAseq | -0.3148 | 0.2727 | |
| SRP193095 | NHSL1 | 57224 | RNAseq | -0.6560 | 0.0000 | |
| SRP219564 | NHSL1 | 57224 | RNAseq | -0.9132 | 0.0708 | |
| TCGA | NHSL1 | 57224 | RNAseq | 0.1608 | 0.0245 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by NHSL1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NHSL1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NHSL1 | 57224 | 3 | 4 | 23 | |
| GSE20123 | NHSL1 | 57224 | 3 | 3 | 24 | |
| GSE43470 | NHSL1 | 57224 | 5 | 0 | 38 | |
| GSE46452 | NHSL1 | 57224 | 3 | 10 | 46 | |
| GSE47630 | NHSL1 | 57224 | 9 | 4 | 27 | |
| GSE54993 | NHSL1 | 57224 | 3 | 2 | 65 | |
| GSE54994 | NHSL1 | 57224 | 8 | 8 | 37 | |
| GSE60625 | NHSL1 | 57224 | 0 | 1 | 10 | |
| GSE74703 | NHSL1 | 57224 | 4 | 0 | 32 | |
| GSE74704 | NHSL1 | 57224 | 1 | 1 | 18 | |
| TCGA | NHSL1 | 57224 | 11 | 17 | 68 |
Total number of gains: 50; Total number of losses: 50; Total Number of normals: 388.
Somatic mutations of NHSL1:
Generating mutation plots.
Highly correlated genes for NHSL1:
Showing top 20/793 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NHSL1 | RNFT1 | 0.807659 | 3 | 0 | 3 |
| NHSL1 | MFN1 | 0.777306 | 3 | 0 | 3 |
| NHSL1 | AP2S1 | 0.765063 | 3 | 0 | 3 |
| NHSL1 | ALG14 | 0.747932 | 3 | 0 | 3 |
| NHSL1 | SLC22A23 | 0.73248 | 4 | 0 | 3 |
| NHSL1 | SLC25A39 | 0.730579 | 3 | 0 | 3 |
| NHSL1 | EPS15 | 0.726363 | 3 | 0 | 3 |
| NHSL1 | ABHD12 | 0.715082 | 3 | 0 | 3 |
| NHSL1 | GTF3C2 | 0.712101 | 3 | 0 | 3 |
| NHSL1 | PSENEN | 0.711372 | 3 | 0 | 3 |
| NHSL1 | ULK3 | 0.711193 | 5 | 0 | 5 |
| NHSL1 | PPP1R13L | 0.711054 | 4 | 0 | 4 |
| NHSL1 | ZDHHC5 | 0.708016 | 6 | 0 | 6 |
| NHSL1 | MITD1 | 0.704597 | 3 | 0 | 3 |
| NHSL1 | SLC10A7 | 0.702667 | 3 | 0 | 3 |
| NHSL1 | TMEM117 | 0.702127 | 4 | 0 | 3 |
| NHSL1 | KIAA1522 | 0.702075 | 3 | 0 | 3 |
| NHSL1 | SH2D4A | 0.701472 | 5 | 0 | 5 |
| NHSL1 | NIPAL1 | 0.700869 | 3 | 0 | 3 |
| NHSL1 | RREB1 | 0.700352 | 5 | 0 | 4 |
For details and further investigation, click here
