| Full name: ankyrin repeat domain 49 | Alias Symbol: FLJ20189|FGIF|GBIF | ||
| Type: protein-coding gene | Cytoband: 11q21 | ||
| Entrez ID: 54851 | HGNC ID: HGNC:25970 | Ensembl Gene: ENSG00000168876 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of ANKRD49:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ANKRD49 | 54851 | 219069_at | -0.0593 | 0.8865 | |
| GSE20347 | ANKRD49 | 54851 | 219069_at | -0.0021 | 0.9930 | |
| GSE23400 | ANKRD49 | 54851 | 219069_at | 0.1473 | 0.0685 | |
| GSE26886 | ANKRD49 | 54851 | 219069_at | -0.2483 | 0.3683 | |
| GSE29001 | ANKRD49 | 54851 | 219069_at | -0.2868 | 0.5437 | |
| GSE38129 | ANKRD49 | 54851 | 219069_at | -0.0517 | 0.7671 | |
| GSE45670 | ANKRD49 | 54851 | 219069_at | -0.0388 | 0.8391 | |
| GSE53622 | ANKRD49 | 54851 | 36071 | -0.1042 | 0.1260 | |
| GSE53624 | ANKRD49 | 54851 | 36071 | 0.0076 | 0.9105 | |
| GSE63941 | ANKRD49 | 54851 | 219069_at | 0.2113 | 0.7220 | |
| GSE77861 | ANKRD49 | 54851 | 219069_at | -0.0208 | 0.9702 | |
| GSE97050 | ANKRD49 | 54851 | A_23_P24365 | 0.2349 | 0.4823 | |
| SRP007169 | ANKRD49 | 54851 | RNAseq | -0.2211 | 0.6285 | |
| SRP008496 | ANKRD49 | 54851 | RNAseq | 0.1570 | 0.5944 | |
| SRP064894 | ANKRD49 | 54851 | RNAseq | -0.2417 | 0.1035 | |
| SRP133303 | ANKRD49 | 54851 | RNAseq | -0.1688 | 0.2791 | |
| SRP159526 | ANKRD49 | 54851 | RNAseq | -0.4247 | 0.2291 | |
| SRP193095 | ANKRD49 | 54851 | RNAseq | -0.5415 | 0.0001 | |
| SRP219564 | ANKRD49 | 54851 | RNAseq | -0.0210 | 0.9427 | |
| TCGA | ANKRD49 | 54851 | RNAseq | -0.0535 | 0.4298 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ANKRD49 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ANKRD49:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ANKRD49 | 54851 | 3 | 9 | 18 | |
| GSE20123 | ANKRD49 | 54851 | 3 | 9 | 18 | |
| GSE43470 | ANKRD49 | 54851 | 2 | 5 | 36 | |
| GSE46452 | ANKRD49 | 54851 | 5 | 24 | 30 | |
| GSE47630 | ANKRD49 | 54851 | 2 | 19 | 19 | |
| GSE54993 | ANKRD49 | 54851 | 8 | 2 | 60 | |
| GSE54994 | ANKRD49 | 54851 | 6 | 18 | 29 | |
| GSE60625 | ANKRD49 | 54851 | 0 | 3 | 8 | |
| GSE74703 | ANKRD49 | 54851 | 1 | 4 | 31 | |
| GSE74704 | ANKRD49 | 54851 | 3 | 5 | 12 | |
| TCGA | ANKRD49 | 54851 | 11 | 43 | 42 |
Total number of gains: 44; Total number of losses: 141; Total Number of normals: 303.
Somatic mutations of ANKRD49:
Generating mutation plots.
Highly correlated genes for ANKRD49:
Showing top 20/285 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ANKRD49 | ZC3HAV1 | 0.738804 | 3 | 0 | 3 |
| ANKRD49 | GTF3C4 | 0.734761 | 3 | 0 | 3 |
| ANKRD49 | C12orf4 | 0.729254 | 3 | 0 | 3 |
| ANKRD49 | FBXL14 | 0.728914 | 4 | 0 | 4 |
| ANKRD49 | DCAF10 | 0.726542 | 3 | 0 | 3 |
| ANKRD49 | ERP27 | 0.710171 | 3 | 0 | 3 |
| ANKRD49 | ZNF451 | 0.704265 | 3 | 0 | 3 |
| ANKRD49 | ACER3 | 0.697577 | 3 | 0 | 3 |
| ANKRD49 | SCML1 | 0.695864 | 3 | 0 | 3 |
| ANKRD49 | COPS4 | 0.690189 | 3 | 0 | 3 |
| ANKRD49 | IREB2 | 0.6901 | 4 | 0 | 3 |
| ANKRD49 | EIF2B1 | 0.68732 | 3 | 0 | 3 |
| ANKRD49 | PALB2 | 0.685687 | 3 | 0 | 3 |
| ANKRD49 | DERL2 | 0.681971 | 3 | 0 | 3 |
| ANKRD49 | ARHGEF7 | 0.679906 | 3 | 0 | 3 |
| ANKRD49 | UFL1 | 0.678769 | 3 | 0 | 3 |
| ANKRD49 | COMMD8 | 0.678282 | 3 | 0 | 3 |
| ANKRD49 | PGRMC1 | 0.671858 | 3 | 0 | 3 |
| ANKRD49 | FAM76B | 0.669755 | 8 | 0 | 7 |
| ANKRD49 | TMEM203 | 0.668097 | 3 | 0 | 3 |
For details and further investigation, click here
