| Full name: disco interacting protein 2 homolog B | Alias Symbol: KIAA1463|FLJ34278 | ||
| Type: protein-coding gene | Cytoband: 12q13.12 | ||
| Entrez ID: 57609 | HGNC ID: HGNC:29284 | Ensembl Gene: ENSG00000066084 | OMIM ID: 611379 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of DIP2B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DIP2B | 57609 | 224872_at | 0.3047 | 0.7120 | |
| GSE26886 | DIP2B | 57609 | 224872_at | 0.0990 | 0.7935 | |
| GSE45670 | DIP2B | 57609 | 224872_at | 0.1837 | 0.2324 | |
| GSE53622 | DIP2B | 57609 | 78799 | 0.1839 | 0.1477 | |
| GSE53624 | DIP2B | 57609 | 78799 | 0.0878 | 0.4695 | |
| GSE63941 | DIP2B | 57609 | 224872_at | 0.0970 | 0.8624 | |
| GSE77861 | DIP2B | 57609 | 224872_at | 0.5310 | 0.0587 | |
| GSE97050 | DIP2B | 57609 | A_23_P401380 | 0.2713 | 0.6083 | |
| SRP007169 | DIP2B | 57609 | RNAseq | 0.2277 | 0.5543 | |
| SRP008496 | DIP2B | 57609 | RNAseq | 0.4180 | 0.0377 | |
| SRP064894 | DIP2B | 57609 | RNAseq | -0.2190 | 0.5029 | |
| SRP133303 | DIP2B | 57609 | RNAseq | 0.3602 | 0.0738 | |
| SRP159526 | DIP2B | 57609 | RNAseq | 0.0587 | 0.8796 | |
| SRP193095 | DIP2B | 57609 | RNAseq | 0.1889 | 0.2431 | |
| SRP219564 | DIP2B | 57609 | RNAseq | -0.3194 | 0.5581 | |
| TCGA | DIP2B | 57609 | RNAseq | 0.2587 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by DIP2B expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DIP2B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DIP2B | 57609 | 8 | 1 | 21 | |
| GSE20123 | DIP2B | 57609 | 8 | 1 | 21 | |
| GSE43470 | DIP2B | 57609 | 4 | 0 | 39 | |
| GSE46452 | DIP2B | 57609 | 8 | 1 | 50 | |
| GSE47630 | DIP2B | 57609 | 11 | 2 | 27 | |
| GSE54993 | DIP2B | 57609 | 0 | 5 | 65 | |
| GSE54994 | DIP2B | 57609 | 4 | 1 | 48 | |
| GSE60625 | DIP2B | 57609 | 0 | 0 | 11 | |
| GSE74703 | DIP2B | 57609 | 4 | 0 | 32 | |
| GSE74704 | DIP2B | 57609 | 5 | 1 | 14 | |
| TCGA | DIP2B | 57609 | 14 | 11 | 71 |
Total number of gains: 66; Total number of losses: 23; Total Number of normals: 399.
Somatic mutations of DIP2B:
Generating mutation plots.
Highly correlated genes for DIP2B:
Showing top 20/337 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DIP2B | LRRC59 | 0.811034 | 3 | 0 | 3 |
| DIP2B | GMCL1 | 0.776607 | 3 | 0 | 3 |
| DIP2B | GTF3C4 | 0.776317 | 3 | 0 | 3 |
| DIP2B | ZNF267 | 0.763625 | 3 | 0 | 3 |
| DIP2B | UEVLD | 0.756889 | 3 | 0 | 3 |
| DIP2B | XPO6 | 0.745294 | 3 | 0 | 3 |
| DIP2B | DHX8 | 0.74351 | 4 | 0 | 4 |
| DIP2B | TRUB1 | 0.739558 | 3 | 0 | 3 |
| DIP2B | MFN1 | 0.724684 | 3 | 0 | 3 |
| DIP2B | ARL4A | 0.722192 | 3 | 0 | 3 |
| DIP2B | TMPO | 0.715583 | 3 | 0 | 3 |
| DIP2B | LCMT2 | 0.712682 | 3 | 0 | 3 |
| DIP2B | USP38 | 0.712399 | 3 | 0 | 3 |
| DIP2B | JAG1 | 0.711927 | 4 | 0 | 3 |
| DIP2B | VPS53 | 0.709196 | 3 | 0 | 3 |
| DIP2B | WDR20 | 0.707808 | 3 | 0 | 3 |
| DIP2B | SCAF8 | 0.707627 | 3 | 0 | 3 |
| DIP2B | TTI2 | 0.702998 | 3 | 0 | 3 |
| DIP2B | CDCP1 | 0.702099 | 3 | 0 | 3 |
| DIP2B | TMTC3 | 0.697956 | 7 | 0 | 6 |
For details and further investigation, click here
