| Full name: mannosidase endo-alpha | Alias Symbol: FLJ12838|mandaselin | ||
| Type: protein-coding gene | Cytoband: 6q16.1 | ||
| Entrez ID: 79694 | HGNC ID: HGNC:21072 | Ensembl Gene: ENSG00000172469 | OMIM ID: 612327 |
| Drug and gene relationship at DGIdb | |||
Expression of MANEA:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MANEA | 79694 | 219003_s_at | 0.1283 | 0.8440 | |
| GSE20347 | MANEA | 79694 | 219003_s_at | 0.0584 | 0.7105 | |
| GSE23400 | MANEA | 79694 | 219003_s_at | 0.1902 | 0.0000 | |
| GSE26886 | MANEA | 79694 | 222805_at | -0.3126 | 0.2600 | |
| GSE29001 | MANEA | 79694 | 219003_s_at | 0.3742 | 0.4585 | |
| GSE38129 | MANEA | 79694 | 219003_s_at | 0.3161 | 0.0197 | |
| GSE45670 | MANEA | 79694 | 222805_at | 0.1360 | 0.4920 | |
| GSE53622 | MANEA | 79694 | 62862 | 0.3697 | 0.0000 | |
| GSE53624 | MANEA | 79694 | 90728 | 0.1177 | 0.2951 | |
| GSE63941 | MANEA | 79694 | 219003_s_at | 0.3321 | 0.7298 | |
| GSE77861 | MANEA | 79694 | 222805_at | 0.1855 | 0.6495 | |
| GSE97050 | MANEA | 79694 | A_24_P187921 | 0.6334 | 0.1976 | |
| SRP007169 | MANEA | 79694 | RNAseq | -0.1937 | 0.5646 | |
| SRP008496 | MANEA | 79694 | RNAseq | -0.0428 | 0.8822 | |
| SRP064894 | MANEA | 79694 | RNAseq | 0.2397 | 0.4423 | |
| SRP133303 | MANEA | 79694 | RNAseq | 0.3440 | 0.0601 | |
| SRP159526 | MANEA | 79694 | RNAseq | 0.2653 | 0.4310 | |
| SRP193095 | MANEA | 79694 | RNAseq | -0.3361 | 0.0062 | |
| SRP219564 | MANEA | 79694 | RNAseq | -0.0420 | 0.9180 | |
| TCGA | MANEA | 79694 | RNAseq | -0.0376 | 0.5210 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by MANEA expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MANEA:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MANEA | 79694 | 1 | 5 | 24 | |
| GSE20123 | MANEA | 79694 | 1 | 4 | 25 | |
| GSE43470 | MANEA | 79694 | 3 | 2 | 38 | |
| GSE46452 | MANEA | 79694 | 2 | 11 | 46 | |
| GSE47630 | MANEA | 79694 | 8 | 6 | 26 | |
| GSE54993 | MANEA | 79694 | 3 | 2 | 65 | |
| GSE54994 | MANEA | 79694 | 8 | 8 | 37 | |
| GSE60625 | MANEA | 79694 | 0 | 1 | 10 | |
| GSE74703 | MANEA | 79694 | 2 | 2 | 32 | |
| GSE74704 | MANEA | 79694 | 0 | 2 | 18 | |
| TCGA | MANEA | 79694 | 5 | 25 | 66 |
Total number of gains: 33; Total number of losses: 68; Total Number of normals: 387.
Somatic mutations of MANEA:
Generating mutation plots.
Highly correlated genes for MANEA:
Showing top 20/511 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MANEA | GTF3C4 | 0.784508 | 3 | 0 | 3 |
| MANEA | KLHL20 | 0.723807 | 3 | 0 | 3 |
| MANEA | C12orf73 | 0.710488 | 3 | 0 | 3 |
| MANEA | ATG12 | 0.702198 | 3 | 0 | 3 |
| MANEA | UTP14C | 0.697768 | 3 | 0 | 3 |
| MANEA | KREMEN1 | 0.694128 | 3 | 0 | 3 |
| MANEA | UBE2K | 0.691551 | 3 | 0 | 3 |
| MANEA | RPS6KB1 | 0.690984 | 3 | 0 | 3 |
| MANEA | MTMR6 | 0.688086 | 5 | 0 | 5 |
| MANEA | DMXL2 | 0.686998 | 3 | 0 | 3 |
| MANEA | TBCC | 0.68639 | 3 | 0 | 3 |
| MANEA | TTI2 | 0.678859 | 3 | 0 | 3 |
| MANEA | OSBPL6 | 0.677982 | 3 | 0 | 3 |
| MANEA | PHF20 | 0.676303 | 3 | 0 | 3 |
| MANEA | ZNRF3 | 0.675081 | 3 | 0 | 3 |
| MANEA | PTCD3 | 0.674844 | 4 | 0 | 4 |
| MANEA | TADA1 | 0.669758 | 3 | 0 | 3 |
| MANEA | STAMBPL1 | 0.669528 | 3 | 0 | 3 |
| MANEA | TBP | 0.666843 | 5 | 0 | 4 |
| MANEA | MGAT5 | 0.664778 | 3 | 0 | 3 |
For details and further investigation, click here
