| Full name: GTP binding protein 1 | Alias Symbol: GP-1|HSPC018 | ||
| Type: protein-coding gene | Cytoband: 22q13.1 | ||
| Entrez ID: 9567 | HGNC ID: HGNC:4669 | Ensembl Gene: ENSG00000100226 | OMIM ID: 602245 |
| Drug and gene relationship at DGIdb | |||
Expression of GTPBP1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GTPBP1 | 9567 | 219357_at | -0.0515 | 0.8843 | |
| GSE20347 | GTPBP1 | 9567 | 219357_at | -0.0073 | 0.9577 | |
| GSE23400 | GTPBP1 | 9567 | 219357_at | -0.1133 | 0.0515 | |
| GSE26886 | GTPBP1 | 9567 | 219357_at | -0.1531 | 0.4179 | |
| GSE29001 | GTPBP1 | 9567 | 219357_at | -0.2064 | 0.5356 | |
| GSE38129 | GTPBP1 | 9567 | 219357_at | -0.1203 | 0.3206 | |
| GSE45670 | GTPBP1 | 9567 | 219357_at | 0.0639 | 0.6571 | |
| GSE53622 | GTPBP1 | 9567 | 86268 | -0.1436 | 0.0226 | |
| GSE53624 | GTPBP1 | 9567 | 86268 | -0.0876 | 0.1242 | |
| GSE63941 | GTPBP1 | 9567 | 219357_at | 0.2603 | 0.5929 | |
| GSE77861 | GTPBP1 | 9567 | 219357_at | 0.2290 | 0.2962 | |
| GSE97050 | GTPBP1 | 9567 | A_24_P168760 | -0.0705 | 0.7432 | |
| SRP007169 | GTPBP1 | 9567 | RNAseq | -0.3760 | 0.4092 | |
| SRP008496 | GTPBP1 | 9567 | RNAseq | -0.6659 | 0.0150 | |
| SRP064894 | GTPBP1 | 9567 | RNAseq | -0.2083 | 0.2519 | |
| SRP133303 | GTPBP1 | 9567 | RNAseq | -0.0537 | 0.5769 | |
| SRP159526 | GTPBP1 | 9567 | RNAseq | -0.2291 | 0.2990 | |
| SRP193095 | GTPBP1 | 9567 | RNAseq | -0.0900 | 0.4529 | |
| SRP219564 | GTPBP1 | 9567 | RNAseq | 0.0537 | 0.8911 | |
| TCGA | GTPBP1 | 9567 | RNAseq | -0.0292 | 0.5070 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by GTPBP1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GTPBP1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GTPBP1 | 9567 | 6 | 5 | 19 | |
| GSE20123 | GTPBP1 | 9567 | 6 | 4 | 20 | |
| GSE43470 | GTPBP1 | 9567 | 5 | 5 | 33 | |
| GSE46452 | GTPBP1 | 9567 | 32 | 2 | 25 | |
| GSE47630 | GTPBP1 | 9567 | 9 | 4 | 27 | |
| GSE54993 | GTPBP1 | 9567 | 3 | 6 | 61 | |
| GSE54994 | GTPBP1 | 9567 | 9 | 7 | 37 | |
| GSE60625 | GTPBP1 | 9567 | 5 | 0 | 6 | |
| GSE74703 | GTPBP1 | 9567 | 5 | 4 | 27 | |
| GSE74704 | GTPBP1 | 9567 | 3 | 2 | 15 | |
| TCGA | GTPBP1 | 9567 | 27 | 15 | 54 |
Total number of gains: 110; Total number of losses: 54; Total Number of normals: 324.
Somatic mutations of GTPBP1:
Generating mutation plots.
Highly correlated genes for GTPBP1:
Showing top 20/251 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GTPBP1 | ARHGAP35 | 0.794762 | 3 | 0 | 3 |
| GTPBP1 | DMWD | 0.778237 | 3 | 0 | 3 |
| GTPBP1 | ZNF830 | 0.774348 | 3 | 0 | 3 |
| GTPBP1 | RABAC1 | 0.758154 | 3 | 0 | 3 |
| GTPBP1 | DNMT3A | 0.741721 | 3 | 0 | 3 |
| GTPBP1 | INPP5B | 0.73997 | 3 | 0 | 3 |
| GTPBP1 | GABBR1 | 0.732138 | 4 | 0 | 4 |
| GTPBP1 | TMEM222 | 0.731647 | 3 | 0 | 3 |
| GTPBP1 | FBXW7 | 0.727745 | 3 | 0 | 3 |
| GTPBP1 | HES4 | 0.72651 | 3 | 0 | 3 |
| GTPBP1 | CIRBP | 0.72519 | 3 | 0 | 3 |
| GTPBP1 | ANKRD11 | 0.724756 | 3 | 0 | 3 |
| GTPBP1 | GMEB2 | 0.723438 | 3 | 0 | 3 |
| GTPBP1 | EXOC3L1 | 0.721211 | 3 | 0 | 3 |
| GTPBP1 | HSPBP1 | 0.721049 | 3 | 0 | 3 |
| GTPBP1 | EEF1D | 0.718363 | 3 | 0 | 3 |
| GTPBP1 | PPP1R15A | 0.71731 | 3 | 0 | 3 |
| GTPBP1 | GRWD1 | 0.711639 | 3 | 0 | 3 |
| GTPBP1 | SMG6 | 0.710277 | 4 | 0 | 4 |
| GTPBP1 | NACC2 | 0.709371 | 3 | 0 | 3 |
For details and further investigation, click here
