HSPBP1

 

Full name: HSPA (Hsp70) binding protein 1 Alias Symbol: HspBP1|FES1
Type: protein-coding gene Cytoband: 19q13.42
Entrez ID: 23640 HGNC ID: HGNC:24989 Ensembl Gene: ENSG00000133265 OMIM ID: 612939
Drug and gene relationship at DGIdb

 

Expression of HSPBP1:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 HSPBP1 23640 202415_s_at 0.4665 0.2040
GSE20347 HSPBP1 23640 202415_s_at 0.1720 0.0829
GSE23400 HSPBP1 23640 202415_s_at 0.1035 0.0911
GSE26886 HSPBP1 23640 202415_s_at 0.3446 0.0570
GSE29001 HSPBP1 23640 202415_s_at 0.1991 0.3378
GSE38129 HSPBP1 23640 202415_s_at 0.3321 0.0002
GSE45670 HSPBP1 23640 202415_s_at 0.2901 0.0041
GSE53622 HSPBP1 23640 27249 0.1441 0.0152
GSE53624 HSPBP1 23640 27249 0.3818 0.0000
GSE63941 HSPBP1 23640 202415_s_at 0.8596 0.0031
GSE77861 HSPBP1 23640 202415_s_at 0.2862 0.1007
GSE97050 HSPBP1 23640 A_23_P10685 0.3361 0.1858
SRP007169 HSPBP1 23640 RNAseq -0.4901 0.1461
SRP008496 HSPBP1 23640 RNAseq -0.7847 0.0012
SRP064894 HSPBP1 23640 RNAseq 0.7812 0.0264
SRP133303 HSPBP1 23640 RNAseq 0.4650 0.0483
SRP159526 HSPBP1 23640 RNAseq 0.6072 0.0435
SRP193095 HSPBP1 23640 RNAseq 0.1926 0.1133
SRP219564 HSPBP1 23640 RNAseq 0.4102 0.2802
TCGA HSPBP1 23640 RNAseq 0.1946 0.0003

Upregulated datasets: 0; Downregulated datasets: 0.  

 

Survival by HSPBP1 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of HSPBP1:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 HSPBP1 23640 3 4 23
GSE20123 HSPBP1 23640 3 3 24
GSE43470 HSPBP1 23640 3 11 29
GSE46452 HSPBP1 23640 45 1 13
GSE47630 HSPBP1 23640 8 6 26
GSE54993 HSPBP1 23640 17 4 49
GSE54994 HSPBP1 23640 4 13 36
GSE60625 HSPBP1 23640 9 0 2
GSE74703 HSPBP1 23640 3 7 26
GSE74704 HSPBP1 23640 3 1 16
TCGA HSPBP1 23640 19 14 63

Total number of gains: 117; Total number of losses: 64; Total Number of normals: 307.  

 

Somatic mutations of HSPBP1:

 

Generating mutation plots.

 

Highly correlated genes for HSPBP1:

 

Showing top 20/1045 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
HSPBP1POGK0.806413303
HSPBP1SLC29A30.762681303
HSPBP1PIF10.753095303
HSPBP1TAF4B0.749864303
HSPBP1M6PR0.749815303
HSPBP1SMAD10.737626303
HSPBP1ZNF6280.733536606
HSPBP1ARHGEF110.728883303
HSPBP1GTPBP10.721049303
HSPBP1TADA10.720859303
HSPBP1ZNF6910.719235303
HSPBP1GSK3A0.714572606
HSPBP1BNIP10.71203403
HSPBP1CORO1C0.7111303
HSPBP1SENP30.709696606
HSPBP1ZNF6680.709141403
HSPBP1PDCD2L0.708815505
HSPBP1CTF10.707673303
HSPBP1TSHR0.702434303
HSPBP1TUBGCP20.702189303

For details and further investigation, click here