| Full name: GULP PTB domain containing engulfment adaptor 1 | Alias Symbol: CED6|CED-6|GULP | ||
| Type: protein-coding gene | Cytoband: 2q32.1-q32.2 | ||
| Entrez ID: 51454 | HGNC ID: HGNC:18649 | Ensembl Gene: ENSG00000144366 | OMIM ID: 608165 |
| Drug and gene relationship at DGIdb | |||
Expression of GULP1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GULP1 | 51454 | 204237_at | -2.3286 | 0.0086 | |
| GSE20347 | GULP1 | 51454 | 204235_s_at | -2.1002 | 0.0000 | |
| GSE23400 | GULP1 | 51454 | 204235_s_at | -1.0126 | 0.0000 | |
| GSE26886 | GULP1 | 51454 | 204235_s_at | -2.5728 | 0.0003 | |
| GSE29001 | GULP1 | 51454 | 204235_s_at | -2.3016 | 0.0004 | |
| GSE38129 | GULP1 | 51454 | 204235_s_at | -1.6072 | 0.0000 | |
| GSE45670 | GULP1 | 51454 | 204237_at | -1.8064 | 0.0034 | |
| GSE53622 | GULP1 | 51454 | 62388 | -1.4372 | 0.0000 | |
| GSE53624 | GULP1 | 51454 | 81177 | -1.7897 | 0.0000 | |
| GSE63941 | GULP1 | 51454 | 204237_at | -1.6675 | 0.3523 | |
| GSE77861 | GULP1 | 51454 | 204235_s_at | -1.0802 | 0.1716 | |
| GSE97050 | GULP1 | 51454 | A_32_P153388 | -1.1087 | 0.0952 | |
| SRP007169 | GULP1 | 51454 | RNAseq | -1.3461 | 0.0471 | |
| SRP008496 | GULP1 | 51454 | RNAseq | -1.5276 | 0.0006 | |
| SRP064894 | GULP1 | 51454 | RNAseq | -1.3322 | 0.0003 | |
| SRP133303 | GULP1 | 51454 | RNAseq | -0.7613 | 0.0144 | |
| SRP159526 | GULP1 | 51454 | RNAseq | -1.3363 | 0.0147 | |
| SRP193095 | GULP1 | 51454 | RNAseq | -1.6391 | 0.0000 | |
| SRP219564 | GULP1 | 51454 | RNAseq | -1.1120 | 0.1373 | |
| TCGA | GULP1 | 51454 | RNAseq | -0.7167 | 0.0001 |
Upregulated datasets: 0; Downregulated datasets: 14.
Survival by GULP1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GULP1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GULP1 | 51454 | 8 | 2 | 20 | |
| GSE20123 | GULP1 | 51454 | 8 | 2 | 20 | |
| GSE43470 | GULP1 | 51454 | 3 | 1 | 39 | |
| GSE46452 | GULP1 | 51454 | 1 | 4 | 54 | |
| GSE47630 | GULP1 | 51454 | 4 | 6 | 30 | |
| GSE54993 | GULP1 | 51454 | 0 | 5 | 65 | |
| GSE54994 | GULP1 | 51454 | 12 | 6 | 35 | |
| GSE60625 | GULP1 | 51454 | 0 | 3 | 8 | |
| GSE74703 | GULP1 | 51454 | 2 | 1 | 33 | |
| GSE74704 | GULP1 | 51454 | 3 | 2 | 15 | |
| TCGA | GULP1 | 51454 | 25 | 7 | 64 |
Total number of gains: 66; Total number of losses: 39; Total Number of normals: 383.
Somatic mutations of GULP1:
Generating mutation plots.
Highly correlated genes for GULP1:
Showing top 20/1482 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GULP1 | LYRM7 | 0.783841 | 3 | 0 | 3 |
| GULP1 | CGNL1 | 0.759251 | 7 | 0 | 7 |
| GULP1 | SMDT1 | 0.738096 | 3 | 0 | 3 |
| GULP1 | HDHD2 | 0.731037 | 4 | 0 | 4 |
| GULP1 | NUCB2 | 0.728546 | 11 | 0 | 11 |
| GULP1 | KAT2B | 0.72676 | 11 | 0 | 11 |
| GULP1 | GALNT12 | 0.721652 | 11 | 0 | 11 |
| GULP1 | ID4 | 0.720472 | 10 | 0 | 10 |
| GULP1 | PTGER3 | 0.718736 | 3 | 0 | 3 |
| GULP1 | COX15 | 0.715862 | 3 | 0 | 3 |
| GULP1 | HOXA3 | 0.713505 | 4 | 0 | 4 |
| GULP1 | SECISBP2L | 0.712351 | 11 | 0 | 11 |
| GULP1 | TBC1D20 | 0.710908 | 4 | 0 | 3 |
| GULP1 | FAM214A | 0.710366 | 6 | 0 | 6 |
| GULP1 | ANKRD35 | 0.707607 | 7 | 0 | 7 |
| GULP1 | MGLL | 0.707605 | 12 | 0 | 11 |
| GULP1 | CPPED1 | 0.706758 | 11 | 0 | 11 |
| GULP1 | CLEC3B | 0.705222 | 3 | 0 | 3 |
| GULP1 | CHN2 | 0.702568 | 3 | 0 | 3 |
| GULP1 | CETN2 | 0.702286 | 3 | 0 | 3 |
For details and further investigation, click here
