| Full name: SECIS binding protein 2 like | Alias Symbol: KIAA0256 | ||
| Type: protein-coding gene | Cytoband: 15q21.1 | ||
| Entrez ID: 9728 | HGNC ID: HGNC:28997 | Ensembl Gene: ENSG00000138593 | OMIM ID: 615756 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of SECISBP2L:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SECISBP2L | 9728 | 212450_at | -0.7202 | 0.0346 | |
| GSE20347 | SECISBP2L | 9728 | 212450_at | -1.4120 | 0.0000 | |
| GSE23400 | SECISBP2L | 9728 | 212450_at | -1.2878 | 0.0000 | |
| GSE26886 | SECISBP2L | 9728 | 212450_at | -1.8697 | 0.0000 | |
| GSE29001 | SECISBP2L | 9728 | 212450_at | -1.1767 | 0.0004 | |
| GSE38129 | SECISBP2L | 9728 | 212450_at | -1.3933 | 0.0000 | |
| GSE45670 | SECISBP2L | 9728 | 212450_at | -1.0200 | 0.0000 | |
| GSE53622 | SECISBP2L | 9728 | 104293 | -1.2992 | 0.0000 | |
| GSE53624 | SECISBP2L | 9728 | 104293 | -1.3397 | 0.0000 | |
| GSE63941 | SECISBP2L | 9728 | 212450_at | -2.2913 | 0.0004 | |
| GSE77861 | SECISBP2L | 9728 | 212450_at | -1.1717 | 0.0204 | |
| GSE97050 | SECISBP2L | 9728 | A_23_P37415 | -0.9839 | 0.0781 | |
| SRP007169 | SECISBP2L | 9728 | RNAseq | -2.0027 | 0.0000 | |
| SRP008496 | SECISBP2L | 9728 | RNAseq | -1.8870 | 0.0000 | |
| SRP064894 | SECISBP2L | 9728 | RNAseq | -1.7369 | 0.0000 | |
| SRP133303 | SECISBP2L | 9728 | RNAseq | -0.9398 | 0.0000 | |
| SRP159526 | SECISBP2L | 9728 | RNAseq | -1.1538 | 0.0000 | |
| SRP193095 | SECISBP2L | 9728 | RNAseq | -1.5906 | 0.0000 | |
| SRP219564 | SECISBP2L | 9728 | RNAseq | -1.0883 | 0.0093 | |
| TCGA | SECISBP2L | 9728 | RNAseq | -0.4559 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 16.
Survival by SECISBP2L expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SECISBP2L:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SECISBP2L | 9728 | 5 | 3 | 22 | |
| GSE20123 | SECISBP2L | 9728 | 5 | 3 | 22 | |
| GSE43470 | SECISBP2L | 9728 | 5 | 4 | 34 | |
| GSE46452 | SECISBP2L | 9728 | 3 | 7 | 49 | |
| GSE47630 | SECISBP2L | 9728 | 8 | 10 | 22 | |
| GSE54993 | SECISBP2L | 9728 | 4 | 6 | 60 | |
| GSE54994 | SECISBP2L | 9728 | 5 | 7 | 41 | |
| GSE60625 | SECISBP2L | 9728 | 4 | 0 | 7 | |
| GSE74703 | SECISBP2L | 9728 | 5 | 3 | 28 | |
| GSE74704 | SECISBP2L | 9728 | 2 | 3 | 15 | |
| TCGA | SECISBP2L | 9728 | 10 | 17 | 69 |
Total number of gains: 56; Total number of losses: 63; Total Number of normals: 369.
Somatic mutations of SECISBP2L:
Generating mutation plots.
Highly correlated genes for SECISBP2L:
Showing top 20/1620 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SECISBP2L | SH3BGRL2 | 0.830534 | 7 | 0 | 7 |
| SECISBP2L | CGNL1 | 0.821699 | 7 | 0 | 7 |
| SECISBP2L | PPP1R3C | 0.808136 | 12 | 0 | 12 |
| SECISBP2L | MGLL | 0.807589 | 12 | 0 | 12 |
| SECISBP2L | SHROOM3 | 0.807191 | 7 | 0 | 7 |
| SECISBP2L | PAQR8 | 0.798885 | 7 | 0 | 7 |
| SECISBP2L | KAT2B | 0.796479 | 13 | 0 | 12 |
| SECISBP2L | GYS2 | 0.794383 | 10 | 0 | 10 |
| SECISBP2L | CTTNBP2 | 0.789029 | 7 | 0 | 7 |
| SECISBP2L | KIAA0232 | 0.787929 | 11 | 0 | 11 |
| SECISBP2L | CAST | 0.786644 | 11 | 0 | 11 |
| SECISBP2L | SFTA2 | 0.786449 | 4 | 0 | 4 |
| SECISBP2L | FAM214A | 0.785702 | 7 | 0 | 7 |
| SECISBP2L | SNORA68 | 0.784876 | 4 | 0 | 4 |
| SECISBP2L | SASH1 | 0.783064 | 12 | 0 | 12 |
| SECISBP2L | FNDC4 | 0.782942 | 11 | 0 | 11 |
| SECISBP2L | TMPRSS11B | 0.781527 | 6 | 0 | 6 |
| SECISBP2L | SPINK7 | 0.781114 | 6 | 0 | 6 |
| SECISBP2L | ANXA9 | 0.780566 | 11 | 0 | 11 |
| SECISBP2L | CYSRT1 | 0.779164 | 6 | 0 | 6 |
For details and further investigation, click here
