| Full name: ATPase H+/K+ transporting subunit alpha | Alias Symbol: ATP6A | ||
| Type: protein-coding gene | Cytoband: 19q13.12 | ||
| Entrez ID: 495 | HGNC ID: HGNC:819 | Ensembl Gene: ENSG00000105675 | OMIM ID: 137216 |
| Drug and gene relationship at DGIdb | |||
Expression of ATP4A:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ATP4A | 495 | 207139_at | -0.2043 | 0.4793 | |
| GSE20347 | ATP4A | 495 | 207139_at | 0.0513 | 0.4327 | |
| GSE23400 | ATP4A | 495 | 207139_at | -0.2086 | 0.0183 | |
| GSE26886 | ATP4A | 495 | 207139_at | -0.1025 | 0.3674 | |
| GSE29001 | ATP4A | 495 | 207139_at | -0.0968 | 0.5911 | |
| GSE38129 | ATP4A | 495 | 207139_at | -0.5989 | 0.1478 | |
| GSE45670 | ATP4A | 495 | 207139_at | -0.1313 | 0.3074 | |
| GSE53622 | ATP4A | 495 | 27844 | 0.0500 | 0.8874 | |
| GSE53624 | ATP4A | 495 | 27844 | -0.0671 | 0.8237 | |
| GSE63941 | ATP4A | 495 | 207139_at | -0.1086 | 0.5534 | |
| GSE77861 | ATP4A | 495 | 207139_at | -0.3208 | 0.0556 | |
| TCGA | ATP4A | 495 | RNAseq | -5.8225 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by ATP4A expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ATP4A:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ATP4A | 495 | 6 | 4 | 20 | |
| GSE20123 | ATP4A | 495 | 6 | 3 | 21 | |
| GSE43470 | ATP4A | 495 | 3 | 7 | 33 | |
| GSE46452 | ATP4A | 495 | 48 | 1 | 10 | |
| GSE47630 | ATP4A | 495 | 9 | 5 | 26 | |
| GSE54993 | ATP4A | 495 | 17 | 3 | 50 | |
| GSE54994 | ATP4A | 495 | 7 | 9 | 37 | |
| GSE60625 | ATP4A | 495 | 9 | 0 | 2 | |
| GSE74703 | ATP4A | 495 | 3 | 4 | 29 | |
| GSE74704 | ATP4A | 495 | 6 | 1 | 13 | |
| TCGA | ATP4A | 495 | 21 | 11 | 64 |
Total number of gains: 135; Total number of losses: 48; Total Number of normals: 305.
Somatic mutations of ATP4A:
Generating mutation plots.
Highly correlated genes for ATP4A:
Showing top 20/435 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ATP4A | CTSE | 0.752337 | 8 | 0 | 8 |
| ATP4A | CLDN18 | 0.741712 | 6 | 0 | 6 |
| ATP4A | CPA2 | 0.734944 | 6 | 0 | 5 |
| ATP4A | MUC6 | 0.71254 | 6 | 0 | 6 |
| ATP4A | TAAR2 | 0.707534 | 3 | 0 | 3 |
| ATP4A | REG1A | 0.697129 | 6 | 0 | 6 |
| ATP4A | CAPN9 | 0.692439 | 5 | 0 | 4 |
| ATP4A | PHGR1 | 0.690181 | 3 | 0 | 3 |
| ATP4A | CCIN | 0.68916 | 5 | 0 | 5 |
| ATP4A | HBM | 0.687021 | 3 | 0 | 3 |
| ATP4A | RBP3 | 0.683982 | 4 | 0 | 3 |
| ATP4A | CHIA | 0.681037 | 10 | 0 | 8 |
| ATP4A | EPB42 | 0.673538 | 4 | 0 | 4 |
| ATP4A | EPS8L3 | 0.672458 | 6 | 0 | 5 |
| ATP4A | TXNDC2 | 0.669846 | 3 | 0 | 3 |
| ATP4A | NR0B2 | 0.669615 | 6 | 0 | 6 |
| ATP4A | SRD5A2 | 0.667983 | 4 | 0 | 3 |
| ATP4A | FUT9 | 0.664427 | 7 | 0 | 6 |
| ATP4A | TULP1 | 0.663982 | 3 | 0 | 3 |
| ATP4A | CCDC154 | 0.661621 | 3 | 0 | 3 |
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