| Full name: HEN methyltransferase 1 | Alias Symbol: FLJ30525|HEN1 | ||
| Type: protein-coding gene | Cytoband: 1p13.3 | ||
| Entrez ID: 113802 | HGNC ID: HGNC:26400 | Ensembl Gene: ENSG00000162639 | OMIM ID: 612178 |
| Drug and gene relationship at DGIdb | |||
Expression of HENMT1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | HENMT1 | 113802 | 225841_at | 1.4784 | 0.0937 | |
| GSE26886 | HENMT1 | 113802 | 225841_at | -0.0181 | 0.9747 | |
| GSE45670 | HENMT1 | 113802 | 225841_at | 1.1619 | 0.0014 | |
| GSE53622 | HENMT1 | 113802 | 52751 | 0.7122 | 0.0000 | |
| GSE53624 | HENMT1 | 113802 | 52751 | 1.2501 | 0.0000 | |
| GSE63941 | HENMT1 | 113802 | 225841_at | 1.1239 | 0.4508 | |
| GSE77861 | HENMT1 | 113802 | 225841_at | 0.1036 | 0.8125 | |
| GSE97050 | HENMT1 | 113802 | A_23_P309361 | 0.4405 | 0.1894 | |
| SRP064894 | HENMT1 | 113802 | RNAseq | 1.4182 | 0.0000 | |
| SRP133303 | HENMT1 | 113802 | RNAseq | 1.4619 | 0.0000 | |
| SRP159526 | HENMT1 | 113802 | RNAseq | 0.9048 | 0.0257 | |
| SRP193095 | HENMT1 | 113802 | RNAseq | 1.1773 | 0.0000 | |
| SRP219564 | HENMT1 | 113802 | RNAseq | 1.3419 | 0.0180 |
Upregulated datasets: 6; Downregulated datasets: 0.
Survival by HENMT1 expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of HENMT1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | HENMT1 | 113802 | 0 | 12 | 18 | |
| GSE20123 | HENMT1 | 113802 | 0 | 11 | 19 | |
| GSE43470 | HENMT1 | 113802 | 0 | 8 | 35 | |
| GSE46452 | HENMT1 | 113802 | 2 | 1 | 56 | |
| GSE47630 | HENMT1 | 113802 | 9 | 5 | 26 | |
| GSE54993 | HENMT1 | 113802 | 0 | 1 | 69 | |
| GSE54994 | HENMT1 | 113802 | 7 | 4 | 42 | |
| GSE60625 | HENMT1 | 113802 | 0 | 0 | 11 | |
| GSE74703 | HENMT1 | 113802 | 0 | 6 | 30 | |
| GSE74704 | HENMT1 | 113802 | 0 | 7 | 13 | |
| TCGA | HENMT1 | 113802 | 8 | 26 | 62 |
Total number of gains: 26; Total number of losses: 81; Total Number of normals: 381.
Somatic mutations of HENMT1:
Generating mutation plots.
Highly correlated genes for HENMT1:
Showing top 20/360 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| HENMT1 | GNPNAT1 | 0.687642 | 3 | 0 | 3 |
| HENMT1 | PAM16 | 0.682127 | 3 | 0 | 3 |
| HENMT1 | TBC1D32 | 0.680571 | 4 | 0 | 3 |
| HENMT1 | PRPS2 | 0.679547 | 3 | 0 | 3 |
| HENMT1 | RRP1B | 0.655941 | 5 | 0 | 4 |
| HENMT1 | C8orf33 | 0.650121 | 3 | 0 | 3 |
| HENMT1 | C12orf49 | 0.649518 | 4 | 0 | 4 |
| HENMT1 | ZBED4 | 0.649233 | 4 | 0 | 4 |
| HENMT1 | NUDT1 | 0.642218 | 5 | 0 | 4 |
| HENMT1 | KIF2C | 0.640971 | 7 | 0 | 5 |
| HENMT1 | SIX4 | 0.63827 | 4 | 0 | 3 |
| HENMT1 | BCL11A | 0.636899 | 3 | 0 | 3 |
| HENMT1 | ZWILCH | 0.635952 | 5 | 0 | 5 |
| HENMT1 | LAMB3 | 0.634537 | 6 | 0 | 5 |
| HENMT1 | RNASET2 | 0.633681 | 3 | 0 | 3 |
| HENMT1 | RBL1 | 0.633299 | 5 | 0 | 4 |
| HENMT1 | NOC4L | 0.630397 | 3 | 0 | 3 |
| HENMT1 | MAGEA4 | 0.630126 | 5 | 0 | 4 |
| HENMT1 | RFC4 | 0.627602 | 5 | 0 | 3 |
| HENMT1 | CCNF | 0.625962 | 6 | 0 | 5 |
For details and further investigation, click here
