NUDT1

 

Full name: nudix hydrolase 1 Alias Symbol: 
Type: protein-coding gene Cytoband: 7p22.3
Entrez ID: 4521 HGNC ID: HGNC:8048 Ensembl Gene: ENSG00000106268 OMIM ID: 600312
Drug and gene relationship at DGIdb

 

Expression of NUDT1:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 NUDT1 4521 204766_s_at 0.9307 0.0148
GSE20347 NUDT1 4521 204766_s_at 1.0630 0.0000
GSE23400 NUDT1 4521 204766_s_at 0.9353 0.0000
GSE26886 NUDT1 4521 204766_s_at 0.9827 0.0000
GSE29001 NUDT1 4521 204766_s_at 0.9466 0.0542
GSE38129 NUDT1 4521 204766_s_at 1.2641 0.0000
GSE45670 NUDT1 4521 204766_s_at 0.7166 0.0002
GSE53622 NUDT1 4521 97883 1.0666 0.0000
GSE53624 NUDT1 4521 97883 1.3529 0.0000
GSE63941 NUDT1 4521 204766_s_at 0.9181 0.1110
GSE77861 NUDT1 4521 204766_s_at 0.6890 0.0026
GSE97050 NUDT1 4521 A_23_P134295 0.6156 0.3775
SRP007169 NUDT1 4521 RNAseq 1.5688 0.0098
SRP008496 NUDT1 4521 RNAseq 1.1701 0.0065
SRP064894 NUDT1 4521 RNAseq 1.4473 0.0001
SRP133303 NUDT1 4521 RNAseq 1.2883 0.0000
SRP159526 NUDT1 4521 RNAseq 1.1935 0.0003
SRP193095 NUDT1 4521 RNAseq 0.5977 0.0026
SRP219564 NUDT1 4521 RNAseq 0.9931 0.0321
TCGA NUDT1 4521 RNAseq 1.0605 0.0000

Upregulated datasets: 10; Downregulated datasets: 0.  

 

Survival by NUDT1 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of NUDT1:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 NUDT1 4521 14 0 16
GSE20123 NUDT1 4521 14 0 16
GSE43470 NUDT1 4521 7 3 33
GSE46452 NUDT1 4521 13 1 45
GSE47630 NUDT1 4521 10 1 29
GSE54993 NUDT1 4521 0 7 63
GSE54994 NUDT1 4521 18 4 31
GSE60625 NUDT1 4521 0 0 11
GSE74703 NUDT1 4521 7 2 27
GSE74704 NUDT1 4521 9 0 11
TCGA NUDT1 4521 56 6 34

Total number of gains: 148; Total number of losses: 24; Total Number of normals: 316.  

 

Somatic mutations of NUDT1:

 

Generating mutation plots.

 

Highly correlated genes for NUDT1:

 

Showing top 20/2097 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
NUDT1CDCA50.814336707
NUDT1CENPN0.80983912012
NUDT1RFC40.78779512012
NUDT1CMSS10.784879606
NUDT1CKS1B0.78413913011
NUDT1RNASEH2A0.7827113012
NUDT1CENPF0.78239812012
NUDT1UBE2T0.780543908
NUDT1KNSTRN0.779575707
NUDT1MYBL20.7773812012
NUDT1DDIAS0.777049606
NUDT1BID0.77540311011
NUDT1CDC450.77020112011
NUDT1EIF3B0.76803812010
NUDT1PNPT10.767499707
NUDT1RAD510.76472211011
NUDT1CENPM0.76431512012
NUDT1CBX30.76351311010
NUDT1RPA30.76114113013
NUDT1CDK10.76099211011

For details and further investigation, click here