KIF2C

 

Full name: kinesin family member 2C Alias Symbol: MCAK|CT139
Type: protein-coding gene Cytoband: 1p34.1
Entrez ID: 11004 HGNC ID: HGNC:6393 Ensembl Gene: ENSG00000142945 OMIM ID: 604538
Drug and gene relationship at DGIdb
Screen Evidence:

 

Expression of KIF2C:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 KIF2C 11004 209408_at 1.6075 0.0453
GSE20347 KIF2C 11004 209408_at 1.5560 0.0000
GSE23400 KIF2C 11004 209408_at 1.0857 0.0000
GSE26886 KIF2C 11004 209408_at 0.7542 0.0085
GSE29001 KIF2C 11004 209408_at 1.5111 0.0000
GSE38129 KIF2C 11004 209408_at 1.9568 0.0000
GSE45670 KIF2C 11004 209408_at 1.5639 0.0000
GSE53622 KIF2C 11004 36303 1.9496 0.0000
GSE53624 KIF2C 11004 36303 2.3192 0.0000
GSE63941 KIF2C 11004 209408_at 3.1168 0.0000
GSE77861 KIF2C 11004 209408_at 0.9524 0.0437
GSE97050 KIF2C 11004 A_23_P34788 1.0146 0.1752
SRP007169 KIF2C 11004 RNAseq 3.7964 0.0000
SRP008496 KIF2C 11004 RNAseq 3.6411 0.0000
SRP064894 KIF2C 11004 RNAseq 2.1790 0.0000
SRP133303 KIF2C 11004 RNAseq 1.8818 0.0000
SRP159526 KIF2C 11004 RNAseq 1.6972 0.0002
SRP193095 KIF2C 11004 RNAseq 1.4528 0.0000
SRP219564 KIF2C 11004 RNAseq 2.3064 0.0034
TCGA KIF2C 11004 RNAseq 1.2694 0.0000

Upregulated datasets: 17; Downregulated datasets: 0.  

 

Survival by KIF2C expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of KIF2C:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 KIF2C 11004 4 3 23
GSE20123 KIF2C 11004 4 2 24
GSE43470 KIF2C 11004 7 2 34
GSE46452 KIF2C 11004 2 1 56
GSE47630 KIF2C 11004 9 3 28
GSE54993 KIF2C 11004 0 1 69
GSE54994 KIF2C 11004 13 2 38
GSE60625 KIF2C 11004 0 0 11
GSE74703 KIF2C 11004 6 1 29
GSE74704 KIF2C 11004 2 0 18
TCGA KIF2C 11004 13 16 67

Total number of gains: 60; Total number of losses: 31; Total Number of normals: 397.  

 

Somatic mutations of KIF2C:

 

Generating mutation plots.

 

Highly correlated genes for KIF2C:

 

Showing top 20/1960 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
KIF2CSTIL0.88061413013
KIF2CKIF4A0.86798911011
KIF2CCDK10.86379112012
KIF2CCDC200.85887513012
KIF2CAURKB0.85664712012
KIF2CUBE2T0.854311808
KIF2CCKS1B0.84763212012
KIF2CDLGAP50.84596913012
KIF2CCDCA80.84034913013
KIF2CNEK20.8375313013
KIF2CTPX20.83602113012
KIF2CNCAPH0.83317909
KIF2CMKI670.83030312012
KIF2CRFC40.82863312012
KIF2CCDKN30.82811613012
KIF2CWDHD10.82790812012
KIF2CDTL0.82654912012
KIF2CUBE2C0.82590713012
KIF2CTRIP130.82324113012
KIF2CCDC450.82321912012

For details and further investigation, click here