| Full name: presequence translocase associated motor 16 | Alias Symbol: Magmas|Tim16|TIMM16 | ||
| Type: protein-coding gene | Cytoband: 16p13.3 | ||
| Entrez ID: 51025 | HGNC ID: HGNC:29679 | Ensembl Gene: ENSG00000217930 | OMIM ID: 614336 |
| Drug and gene relationship at DGIdb | |||
Expression of PAM16:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PAM16 | 51025 | 218969_at | 0.5605 | 0.0726 | |
| GSE20347 | PAM16 | 51025 | 218969_at | 0.5552 | 0.0000 | |
| GSE23400 | PAM16 | 51025 | 218969_at | 0.3489 | 0.0000 | |
| GSE26886 | PAM16 | 51025 | 218969_at | 0.6881 | 0.0001 | |
| GSE29001 | PAM16 | 51025 | 218969_at | 0.1863 | 0.3302 | |
| GSE38129 | PAM16 | 51025 | 218969_at | 0.5441 | 0.0000 | |
| GSE45670 | PAM16 | 51025 | 218969_at | 0.3047 | 0.0023 | |
| GSE63941 | PAM16 | 51025 | 218969_at | 0.9127 | 0.0006 | |
| GSE77861 | PAM16 | 51025 | 218969_at | 0.3919 | 0.0209 | |
| GSE97050 | PAM16 | 51025 | A_23_P206830 | 0.3067 | 0.5572 | |
| SRP007169 | PAM16 | 51025 | RNAseq | 0.2114 | 0.6755 | |
| SRP008496 | PAM16 | 51025 | RNAseq | 0.2724 | 0.4119 | |
| SRP064894 | PAM16 | 51025 | RNAseq | 0.6258 | 0.0523 | |
| SRP133303 | PAM16 | 51025 | RNAseq | 0.6539 | 0.0026 | |
| SRP159526 | PAM16 | 51025 | RNAseq | 0.2896 | 0.3342 | |
| SRP193095 | PAM16 | 51025 | RNAseq | 0.3780 | 0.0037 | |
| SRP219564 | PAM16 | 51025 | RNAseq | 0.6581 | 0.1700 |
Upregulated datasets: 0; Downregulated datasets: 0.
Copy number change of PAM16:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PAM16 | 51025 | 5 | 5 | 20 | |
| GSE20123 | PAM16 | 51025 | 5 | 4 | 21 | |
| GSE43470 | PAM16 | 51025 | 5 | 6 | 32 | |
| GSE46452 | PAM16 | 51025 | 38 | 1 | 20 | |
| GSE47630 | PAM16 | 51025 | 13 | 6 | 21 | |
| GSE54993 | PAM16 | 51025 | 3 | 5 | 62 | |
| GSE54994 | PAM16 | 51025 | 5 | 9 | 39 | |
| GSE60625 | PAM16 | 51025 | 4 | 0 | 7 | |
| GSE74703 | PAM16 | 51025 | 5 | 4 | 27 | |
| GSE74704 | PAM16 | 51025 | 3 | 2 | 15 | |
| TCGA | PAM16 | 51025 | 19 | 13 | 64 |
Total number of gains: 105; Total number of losses: 55; Total Number of normals: 328.
Somatic mutations of PAM16:
Generating mutation plots.
Highly correlated genes for PAM16:
Showing top 20/1182 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PAM16 | SCYL1 | 0.740452 | 3 | 0 | 3 |
| PAM16 | RHEBL1 | 0.72106 | 4 | 0 | 4 |
| PAM16 | RNPS1 | 0.703988 | 9 | 0 | 8 |
| PAM16 | ARVCF | 0.702259 | 3 | 0 | 3 |
| PAM16 | EME1 | 0.698435 | 6 | 0 | 6 |
| PAM16 | POLR2H | 0.697904 | 8 | 0 | 8 |
| PAM16 | NAA38 | 0.690986 | 3 | 0 | 3 |
| PAM16 | ANKRD52 | 0.69 | 4 | 0 | 4 |
| PAM16 | KIF2C | 0.684166 | 8 | 0 | 7 |
| PAM16 | HENMT1 | 0.682127 | 3 | 0 | 3 |
| PAM16 | PGAM5 | 0.681259 | 3 | 0 | 3 |
| PAM16 | MED19 | 0.678308 | 3 | 0 | 3 |
| PAM16 | STIL | 0.678218 | 7 | 0 | 7 |
| PAM16 | AUNIP | 0.678015 | 9 | 0 | 8 |
| PAM16 | PSMG3 | 0.67588 | 5 | 0 | 5 |
| PAM16 | MYBL2 | 0.675451 | 10 | 0 | 10 |
| PAM16 | NOP2 | 0.674236 | 9 | 0 | 9 |
| PAM16 | MRGBP | 0.671726 | 8 | 0 | 8 |
| PAM16 | CDT1 | 0.671171 | 9 | 0 | 9 |
| PAM16 | NXT1 | 0.670311 | 8 | 0 | 7 |
For details and further investigation, click here
