| Full name: lysine rich nucleolar protein 1 | Alias Symbol: 101F10.1|FAM191A|TSG118 | ||
| Type: protein-coding gene | Cytoband: 16p12.3 | ||
| Entrez ID: 400506 | HGNC ID: HGNC:34404 | Ensembl Gene: ENSG00000103550 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of KNOP1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | KNOP1 | 400506 | 229558_at | 0.8045 | 0.0540 | |
| GSE20347 | KNOP1 | 400506 | 213235_at | 0.1933 | 0.0751 | |
| GSE23400 | KNOP1 | 400506 | 213235_at | 0.1035 | 0.0276 | |
| GSE26886 | KNOP1 | 400506 | 213235_at | 0.7369 | 0.0000 | |
| GSE29001 | KNOP1 | 400506 | 213235_at | 0.8928 | 0.0075 | |
| GSE38129 | KNOP1 | 400506 | 213235_at | 0.4764 | 0.0000 | |
| GSE45670 | KNOP1 | 400506 | 213235_at | 0.8026 | 0.0000 | |
| GSE63941 | KNOP1 | 400506 | 213237_at | 1.0011 | 0.0143 | |
| GSE77861 | KNOP1 | 400506 | 213235_at | 0.2370 | 0.1200 | |
| SRP007169 | KNOP1 | 400506 | RNAseq | 1.4307 | 0.0001 | |
| SRP008496 | KNOP1 | 400506 | RNAseq | 1.2102 | 0.0001 | |
| SRP064894 | KNOP1 | 400506 | RNAseq | 0.7322 | 0.0000 | |
| SRP133303 | KNOP1 | 400506 | RNAseq | 0.5762 | 0.0002 | |
| SRP159526 | KNOP1 | 400506 | RNAseq | 0.8145 | 0.0003 | |
| SRP193095 | KNOP1 | 400506 | RNAseq | 0.4137 | 0.0000 | |
| SRP219564 | KNOP1 | 400506 | RNAseq | 0.7671 | 0.0055 |
Upregulated datasets: 3; Downregulated datasets: 0.
Copy number change of KNOP1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | KNOP1 | 400506 | 6 | 3 | 21 | |
| GSE20123 | KNOP1 | 400506 | 6 | 2 | 22 | |
| GSE43470 | KNOP1 | 400506 | 3 | 3 | 37 | |
| GSE46452 | KNOP1 | 400506 | 38 | 1 | 20 | |
| GSE47630 | KNOP1 | 400506 | 11 | 6 | 23 | |
| GSE54993 | KNOP1 | 400506 | 3 | 5 | 62 | |
| GSE54994 | KNOP1 | 400506 | 3 | 10 | 40 | |
| GSE60625 | KNOP1 | 400506 | 4 | 0 | 7 | |
| GSE74703 | KNOP1 | 400506 | 3 | 2 | 31 | |
| GSE74704 | KNOP1 | 400506 | 3 | 1 | 16 | |
| TCGA | KNOP1 | 400506 | 20 | 12 | 64 |
Total number of gains: 100; Total number of losses: 45; Total Number of normals: 343.
Somatic mutations of KNOP1:
Generating mutation plots.
Highly correlated genes for KNOP1:
Showing top 20/798 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| KNOP1 | QSOX2 | 0.745429 | 4 | 0 | 4 |
| KNOP1 | PABPC1L | 0.744106 | 3 | 0 | 3 |
| KNOP1 | SLC45A4 | 0.729194 | 3 | 0 | 3 |
| KNOP1 | HES6 | 0.72854 | 3 | 0 | 3 |
| KNOP1 | MTBP | 0.718485 | 3 | 0 | 3 |
| KNOP1 | MRPL14 | 0.712611 | 3 | 0 | 3 |
| KNOP1 | GPATCH4 | 0.712162 | 3 | 0 | 3 |
| KNOP1 | HS6ST1 | 0.711061 | 3 | 0 | 3 |
| KNOP1 | DOHH | 0.710666 | 3 | 0 | 3 |
| KNOP1 | CHTF18 | 0.707182 | 5 | 0 | 5 |
| KNOP1 | WDR34 | 0.706808 | 3 | 0 | 3 |
| KNOP1 | B3GALT6 | 0.705917 | 3 | 0 | 3 |
| KNOP1 | CMSS1 | 0.688231 | 4 | 0 | 4 |
| KNOP1 | CORO7 | 0.682991 | 3 | 0 | 3 |
| KNOP1 | EXOSC3 | 0.681377 | 3 | 0 | 3 |
| KNOP1 | MTERF3 | 0.678063 | 5 | 0 | 4 |
| KNOP1 | NOP14 | 0.677979 | 3 | 0 | 3 |
| KNOP1 | CCM2 | 0.676557 | 3 | 0 | 3 |
| KNOP1 | RIOK1 | 0.674473 | 4 | 0 | 4 |
| KNOP1 | CTU2 | 0.666334 | 4 | 0 | 4 |
For details and further investigation, click here
