| Full name: histidine triad nucleotide binding protein 2 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 9p13.3 | ||
| Entrez ID: 84681 | HGNC ID: HGNC:18344 | Ensembl Gene: ENSG00000137133 | OMIM ID: 609997 |
| Drug and gene relationship at DGIdb | |||
Expression of HINT2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | HINT2 | 84681 | 224415_s_at | -0.1628 | 0.6578 | |
| GSE26886 | HINT2 | 84681 | 224415_s_at | 0.6216 | 0.0094 | |
| GSE45670 | HINT2 | 84681 | 224415_s_at | 0.0992 | 0.5519 | |
| GSE53622 | HINT2 | 84681 | 33016 | -0.0426 | 0.6019 | |
| GSE53624 | HINT2 | 84681 | 33016 | 0.1576 | 0.0554 | |
| GSE63941 | HINT2 | 84681 | 224415_s_at | 0.4682 | 0.4156 | |
| GSE77861 | HINT2 | 84681 | 224415_s_at | -0.0604 | 0.8454 | |
| GSE97050 | HINT2 | 84681 | A_23_P157784 | -0.0977 | 0.7876 | |
| SRP007169 | HINT2 | 84681 | RNAseq | -0.5561 | 0.3635 | |
| SRP008496 | HINT2 | 84681 | RNAseq | -0.6166 | 0.0910 | |
| SRP064894 | HINT2 | 84681 | RNAseq | 0.8590 | 0.0335 | |
| SRP133303 | HINT2 | 84681 | RNAseq | -0.2618 | 0.0968 | |
| SRP159526 | HINT2 | 84681 | RNAseq | 0.1586 | 0.6229 | |
| SRP193095 | HINT2 | 84681 | RNAseq | 0.0113 | 0.9577 | |
| SRP219564 | HINT2 | 84681 | RNAseq | 0.4360 | 0.2491 | |
| TCGA | HINT2 | 84681 | RNAseq | -0.1132 | 0.3906 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by HINT2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of HINT2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | HINT2 | 84681 | 3 | 12 | 15 | |
| GSE20123 | HINT2 | 84681 | 3 | 12 | 15 | |
| GSE43470 | HINT2 | 84681 | 3 | 10 | 30 | |
| GSE46452 | HINT2 | 84681 | 6 | 15 | 38 | |
| GSE47630 | HINT2 | 84681 | 1 | 20 | 19 | |
| GSE54993 | HINT2 | 84681 | 6 | 0 | 64 | |
| GSE54994 | HINT2 | 84681 | 5 | 12 | 36 | |
| GSE60625 | HINT2 | 84681 | 0 | 0 | 11 | |
| GSE74703 | HINT2 | 84681 | 2 | 7 | 27 | |
| GSE74704 | HINT2 | 84681 | 0 | 10 | 10 | |
| TCGA | HINT2 | 84681 | 17 | 44 | 35 |
Total number of gains: 46; Total number of losses: 142; Total Number of normals: 300.
Somatic mutations of HINT2:
Generating mutation plots.
Highly correlated genes for HINT2:
Showing top 20/188 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| HINT2 | SCMH1 | 0.748341 | 3 | 0 | 3 |
| HINT2 | PLEKHB1 | 0.739293 | 3 | 0 | 3 |
| HINT2 | SYNE1 | 0.73757 | 3 | 0 | 3 |
| HINT2 | ANKS1A | 0.727886 | 3 | 0 | 3 |
| HINT2 | WFS1 | 0.72297 | 3 | 0 | 3 |
| HINT2 | ADARB1 | 0.713678 | 3 | 0 | 3 |
| HINT2 | DIAPH2 | 0.70967 | 3 | 0 | 3 |
| HINT2 | LDOC1 | 0.707788 | 3 | 0 | 3 |
| HINT2 | FLNA | 0.701079 | 3 | 0 | 3 |
| HINT2 | RNF38 | 0.700781 | 3 | 0 | 3 |
| HINT2 | ZNF704 | 0.694422 | 3 | 0 | 3 |
| HINT2 | TPPP | 0.693133 | 3 | 0 | 3 |
| HINT2 | PI16 | 0.692354 | 3 | 0 | 3 |
| HINT2 | ZNF358 | 0.691543 | 3 | 0 | 3 |
| HINT2 | RBMX2 | 0.690582 | 3 | 0 | 3 |
| HINT2 | RNF115 | 0.686169 | 3 | 0 | 3 |
| HINT2 | INMT | 0.685531 | 3 | 0 | 3 |
| HINT2 | NHSL2 | 0.683362 | 3 | 0 | 3 |
| HINT2 | POU6F1 | 0.680482 | 3 | 0 | 3 |
| HINT2 | HAND2 | 0.676073 | 3 | 0 | 3 |
For details and further investigation, click here
