| Full name: Scm polycomb group protein homolog 1 | Alias Symbol: Scml3 | ||
| Type: protein-coding gene | Cytoband: 1p34.2 | ||
| Entrez ID: 22955 | HGNC ID: HGNC:19003 | Ensembl Gene: ENSG00000010803 | OMIM ID: 616396 |
| Drug and gene relationship at DGIdb | |||
Expression of SCMH1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SCMH1 | 22955 | 221216_s_at | -0.0809 | 0.9277 | |
| GSE20347 | SCMH1 | 22955 | 221216_s_at | 0.1070 | 0.5664 | |
| GSE23400 | SCMH1 | 22955 | 221216_s_at | -0.0570 | 0.4536 | |
| GSE26886 | SCMH1 | 22955 | 221216_s_at | 0.5588 | 0.0023 | |
| GSE29001 | SCMH1 | 22955 | 221216_s_at | 0.1391 | 0.5978 | |
| GSE38129 | SCMH1 | 22955 | 221216_s_at | -0.2035 | 0.2654 | |
| GSE45670 | SCMH1 | 22955 | 221216_s_at | -0.3126 | 0.0327 | |
| GSE53622 | SCMH1 | 22955 | 1120 | -0.0195 | 0.8818 | |
| GSE53624 | SCMH1 | 22955 | 1120 | 0.0643 | 0.5371 | |
| GSE63941 | SCMH1 | 22955 | 221216_s_at | 0.0487 | 0.9271 | |
| GSE77861 | SCMH1 | 22955 | 221216_s_at | -0.0734 | 0.7909 | |
| GSE97050 | SCMH1 | 22955 | A_23_P12477 | -0.2598 | 0.4490 | |
| SRP007169 | SCMH1 | 22955 | RNAseq | 0.1532 | 0.7019 | |
| SRP008496 | SCMH1 | 22955 | RNAseq | 0.4595 | 0.0868 | |
| SRP064894 | SCMH1 | 22955 | RNAseq | 0.3437 | 0.0521 | |
| SRP133303 | SCMH1 | 22955 | RNAseq | 0.1161 | 0.5419 | |
| SRP159526 | SCMH1 | 22955 | RNAseq | 0.6079 | 0.1638 | |
| SRP193095 | SCMH1 | 22955 | RNAseq | 0.5396 | 0.0000 | |
| SRP219564 | SCMH1 | 22955 | RNAseq | 0.1549 | 0.7834 | |
| TCGA | SCMH1 | 22955 | RNAseq | -0.2659 | 0.0001 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by SCMH1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SCMH1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SCMH1 | 22955 | 3 | 4 | 23 | |
| GSE20123 | SCMH1 | 22955 | 2 | 3 | 25 | |
| GSE43470 | SCMH1 | 22955 | 7 | 2 | 34 | |
| GSE46452 | SCMH1 | 22955 | 3 | 1 | 55 | |
| GSE47630 | SCMH1 | 22955 | 9 | 2 | 29 | |
| GSE54993 | SCMH1 | 22955 | 0 | 1 | 69 | |
| GSE54994 | SCMH1 | 22955 | 13 | 2 | 38 | |
| GSE60625 | SCMH1 | 22955 | 0 | 0 | 11 | |
| GSE74703 | SCMH1 | 22955 | 6 | 1 | 29 | |
| GSE74704 | SCMH1 | 22955 | 1 | 0 | 19 | |
| TCGA | SCMH1 | 22955 | 16 | 16 | 64 |
Total number of gains: 60; Total number of losses: 32; Total Number of normals: 396.
Somatic mutations of SCMH1:
Generating mutation plots.
Highly correlated genes for SCMH1:
Showing top 20/914 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SCMH1 | ZSCAN21 | 0.781567 | 3 | 0 | 3 |
| SCMH1 | TMEM205 | 0.768111 | 3 | 0 | 3 |
| SCMH1 | LNP1 | 0.761631 | 4 | 0 | 4 |
| SCMH1 | EBAG9 | 0.761165 | 3 | 0 | 3 |
| SCMH1 | HINT2 | 0.748341 | 3 | 0 | 3 |
| SCMH1 | KCNB1 | 0.747119 | 3 | 0 | 3 |
| SCMH1 | RPS27 | 0.742164 | 3 | 0 | 3 |
| SCMH1 | HSPB7 | 0.734189 | 5 | 0 | 4 |
| SCMH1 | STXBP4 | 0.733649 | 3 | 0 | 3 |
| SCMH1 | ELP2 | 0.729787 | 3 | 0 | 3 |
| SCMH1 | IQUB | 0.729237 | 3 | 0 | 3 |
| SCMH1 | DLEU7 | 0.729019 | 3 | 0 | 3 |
| SCMH1 | HTR2B | 0.722862 | 5 | 0 | 5 |
| SCMH1 | PITPNM2 | 0.721176 | 3 | 0 | 3 |
| SCMH1 | TSNARE1 | 0.718877 | 5 | 0 | 4 |
| SCMH1 | PMPCB | 0.717337 | 3 | 0 | 3 |
| SCMH1 | ZNF703 | 0.715807 | 3 | 0 | 3 |
| SCMH1 | LSM11 | 0.714686 | 4 | 0 | 3 |
| SCMH1 | ICAM5 | 0.713279 | 3 | 0 | 3 |
| SCMH1 | B3GALT6 | 0.712033 | 3 | 0 | 3 |
For details and further investigation, click here
