| Full name: immunoglobulin superfamily DCC subclass member 3 | Alias Symbol: HsT18880 | ||
| Type: protein-coding gene | Cytoband: 15q22.31 | ||
| Entrez ID: 9543 | HGNC ID: HGNC:9700 | Ensembl Gene: ENSG00000174498 | OMIM ID: 604184 |
| Drug and gene relationship at DGIdb | |||
Expression of IGDCC3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | IGDCC3 | 9543 | 232037_at | -0.0711 | 0.7683 | |
| GSE26886 | IGDCC3 | 9543 | 232037_at | -0.0310 | 0.7655 | |
| GSE45670 | IGDCC3 | 9543 | 232037_at | 0.0062 | 0.9589 | |
| GSE53622 | IGDCC3 | 9543 | 60836 | 0.4323 | 0.0000 | |
| GSE53624 | IGDCC3 | 9543 | 60836 | 0.4184 | 0.0000 | |
| GSE63941 | IGDCC3 | 9543 | 232037_at | 0.3630 | 0.0034 | |
| GSE77861 | IGDCC3 | 9543 | 232037_at | -0.1182 | 0.4545 | |
| TCGA | IGDCC3 | 9543 | RNAseq | -1.5348 | 0.0082 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by IGDCC3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of IGDCC3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | IGDCC3 | 9543 | 7 | 3 | 20 | |
| GSE20123 | IGDCC3 | 9543 | 7 | 3 | 20 | |
| GSE43470 | IGDCC3 | 9543 | 4 | 6 | 33 | |
| GSE46452 | IGDCC3 | 9543 | 3 | 7 | 49 | |
| GSE47630 | IGDCC3 | 9543 | 8 | 10 | 22 | |
| GSE54993 | IGDCC3 | 9543 | 5 | 6 | 59 | |
| GSE54994 | IGDCC3 | 9543 | 6 | 7 | 40 | |
| GSE60625 | IGDCC3 | 9543 | 4 | 0 | 7 | |
| GSE74703 | IGDCC3 | 9543 | 4 | 3 | 29 | |
| GSE74704 | IGDCC3 | 9543 | 3 | 3 | 14 | |
| TCGA | IGDCC3 | 9543 | 10 | 16 | 70 |
Total number of gains: 61; Total number of losses: 64; Total Number of normals: 363.
Somatic mutations of IGDCC3:
Generating mutation plots.
Highly correlated genes for IGDCC3:
Showing top 20/156 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| IGDCC3 | C10orf90 | 0.744639 | 3 | 0 | 3 |
| IGDCC3 | GSX1 | 0.715311 | 4 | 0 | 4 |
| IGDCC3 | PRSS37 | 0.68643 | 3 | 0 | 3 |
| IGDCC3 | CASC17 | 0.683296 | 3 | 0 | 3 |
| IGDCC3 | ZSCAN10 | 0.67991 | 4 | 0 | 4 |
| IGDCC3 | ADRB3 | 0.662783 | 4 | 0 | 4 |
| IGDCC3 | SLC25A18 | 0.652978 | 3 | 0 | 3 |
| IGDCC3 | BCAN | 0.641574 | 4 | 0 | 4 |
| IGDCC3 | SERPINA4 | 0.633692 | 4 | 0 | 4 |
| IGDCC3 | STAC2 | 0.632001 | 3 | 0 | 3 |
| IGDCC3 | RAX | 0.628354 | 4 | 0 | 4 |
| IGDCC3 | GJD3 | 0.625934 | 4 | 0 | 3 |
| IGDCC3 | LINC01015 | 0.624156 | 3 | 0 | 3 |
| IGDCC3 | PHGR1 | 0.624083 | 3 | 0 | 3 |
| IGDCC3 | SGK2 | 0.615732 | 3 | 0 | 3 |
| IGDCC3 | HNF1B | 0.614952 | 4 | 0 | 3 |
| IGDCC3 | TGM6 | 0.612718 | 3 | 0 | 3 |
| IGDCC3 | SORCS3-AS1 | 0.61062 | 4 | 0 | 4 |
| IGDCC3 | GGN | 0.602406 | 5 | 0 | 4 |
| IGDCC3 | CACNA1G | 0.601077 | 4 | 0 | 3 |
For details and further investigation, click here
