| Full name: heterogeneous nuclear ribonucleoprotein D | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 4q21.22 | ||
| Entrez ID: 3184 | HGNC ID: HGNC:5036 | Ensembl Gene: ENSG00000138668 | OMIM ID: 601324 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of HNRNPD:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | HNRNPD | 3184 | 221481_x_at | 0.4200 | 0.1185 | |
| GSE20347 | HNRNPD | 3184 | 221481_x_at | 0.3652 | 0.0009 | |
| GSE23400 | HNRNPD | 3184 | 221481_x_at | 0.4156 | 0.0000 | |
| GSE26886 | HNRNPD | 3184 | 221481_x_at | 0.3457 | 0.0360 | |
| GSE29001 | HNRNPD | 3184 | 221481_x_at | 0.3570 | 0.0100 | |
| GSE38129 | HNRNPD | 3184 | 221481_x_at | 0.3169 | 0.0001 | |
| GSE45670 | HNRNPD | 3184 | 221481_x_at | 0.0101 | 0.9402 | |
| GSE53622 | HNRNPD | 3184 | 16281 | 0.2211 | 0.0000 | |
| GSE53624 | HNRNPD | 3184 | 16281 | 0.3349 | 0.0000 | |
| GSE63941 | HNRNPD | 3184 | 221481_x_at | 0.4245 | 0.0673 | |
| GSE77861 | HNRNPD | 3184 | 221481_x_at | 0.2933 | 0.0930 | |
| GSE97050 | HNRNPD | 3184 | A_23_P58353 | -0.1104 | 0.8197 | |
| SRP007169 | HNRNPD | 3184 | RNAseq | 1.4530 | 0.0001 | |
| SRP008496 | HNRNPD | 3184 | RNAseq | 1.0347 | 0.0013 | |
| SRP064894 | HNRNPD | 3184 | RNAseq | 0.1340 | 0.2997 | |
| SRP133303 | HNRNPD | 3184 | RNAseq | 0.2566 | 0.0763 | |
| SRP159526 | HNRNPD | 3184 | RNAseq | 0.4131 | 0.2149 | |
| SRP193095 | HNRNPD | 3184 | RNAseq | 0.0828 | 0.3247 | |
| SRP219564 | HNRNPD | 3184 | RNAseq | 0.2162 | 0.3486 | |
| TCGA | HNRNPD | 3184 | RNAseq | 0.1297 | 0.0019 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by HNRNPD expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of HNRNPD:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | HNRNPD | 3184 | 1 | 11 | 18 | |
| GSE20123 | HNRNPD | 3184 | 1 | 11 | 18 | |
| GSE43470 | HNRNPD | 3184 | 0 | 13 | 30 | |
| GSE46452 | HNRNPD | 3184 | 1 | 36 | 22 | |
| GSE47630 | HNRNPD | 3184 | 0 | 20 | 20 | |
| GSE54993 | HNRNPD | 3184 | 8 | 0 | 62 | |
| GSE54994 | HNRNPD | 3184 | 1 | 9 | 43 | |
| GSE60625 | HNRNPD | 3184 | 0 | 0 | 11 | |
| GSE74703 | HNRNPD | 3184 | 0 | 11 | 25 | |
| GSE74704 | HNRNPD | 3184 | 1 | 6 | 13 | |
| TCGA | HNRNPD | 3184 | 11 | 35 | 50 |
Total number of gains: 24; Total number of losses: 152; Total Number of normals: 312.
Somatic mutations of HNRNPD:
Generating mutation plots.
Highly correlated genes for HNRNPD:
Showing top 20/568 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| HNRNPD | SPATA2 | 0.682229 | 3 | 0 | 3 |
| HNRNPD | FAM24B | 0.675054 | 3 | 0 | 3 |
| HNRNPD | NDUFB9 | 0.668602 | 3 | 0 | 3 |
| HNRNPD | GLRX5 | 0.654781 | 6 | 0 | 5 |
| HNRNPD | RIBC2 | 0.647518 | 3 | 0 | 3 |
| HNRNPD | HNRNPA2B1 | 0.644739 | 11 | 0 | 11 |
| HNRNPD | UBE2S | 0.644633 | 3 | 0 | 3 |
| HNRNPD | JTB | 0.632658 | 3 | 0 | 3 |
| HNRNPD | SLC25A19 | 0.629863 | 3 | 0 | 3 |
| HNRNPD | RBM28 | 0.628025 | 6 | 0 | 6 |
| HNRNPD | U2SURP | 0.625532 | 9 | 0 | 7 |
| HNRNPD | MRPS26 | 0.625216 | 3 | 0 | 3 |
| HNRNPD | TBPL1 | 0.620956 | 6 | 0 | 4 |
| HNRNPD | TSPAN15 | 0.618907 | 3 | 0 | 3 |
| HNRNPD | INSR | 0.61811 | 5 | 0 | 4 |
| HNRNPD | LSM1 | 0.617823 | 4 | 0 | 3 |
| HNRNPD | SRRT | 0.616726 | 9 | 0 | 7 |
| HNRNPD | HNRNPR | 0.615726 | 10 | 0 | 8 |
| HNRNPD | TMEM70 | 0.615201 | 4 | 0 | 4 |
| HNRNPD | PDS5B | 0.612257 | 5 | 0 | 4 |
For details and further investigation, click here
