TMEM70

 

Full name: transmembrane protein 70 Alias Symbol: FLJ20533
Type: protein-coding gene Cytoband: 8q21.11
Entrez ID: 54968 HGNC ID: HGNC:26050 Ensembl Gene: ENSG00000175606 OMIM ID: 612418
Drug and gene relationship at DGIdb

 

Expression of TMEM70:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 TMEM70 54968 219449_s_at 0.5776 0.0897
GSE20347 TMEM70 54968 219449_s_at 0.7687 0.0001
GSE23400 TMEM70 54968 219449_s_at 0.6253 0.0000
GSE26886 TMEM70 54968 219449_s_at -0.3835 0.1282
GSE29001 TMEM70 54968 219449_s_at 0.7408 0.0280
GSE38129 TMEM70 54968 219449_s_at 0.5557 0.0052
GSE45670 TMEM70 54968 219449_s_at 0.3490 0.0796
GSE53622 TMEM70 54968 135996 -0.2264 0.0131
GSE53624 TMEM70 54968 135996 0.1211 0.3237
GSE63941 TMEM70 54968 219449_s_at 0.2336 0.5988
GSE77861 TMEM70 54968 219449_s_at 0.2160 0.5374
SRP007169 TMEM70 54968 RNAseq 0.0237 0.9570
SRP008496 TMEM70 54968 RNAseq -0.0080 0.9781
SRP064894 TMEM70 54968 RNAseq 0.4328 0.0309
SRP133303 TMEM70 54968 RNAseq 0.4902 0.0000
SRP159526 TMEM70 54968 RNAseq 0.4859 0.0497
SRP193095 TMEM70 54968 RNAseq 0.2022 0.1384
SRP219564 TMEM70 54968 RNAseq 0.0260 0.9504
TCGA TMEM70 54968 RNAseq -0.2399 0.0000

Upregulated datasets: 0; Downregulated datasets: 0.  

 

Survival by TMEM70 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of TMEM70:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 TMEM70 54968 15 0 15
GSE20123 TMEM70 54968 16 0 14
GSE43470 TMEM70 54968 18 1 24
GSE46452 TMEM70 54968 21 1 37
GSE47630 TMEM70 54968 23 0 17
GSE54993 TMEM70 54968 0 19 51
GSE54994 TMEM70 54968 30 0 23
GSE60625 TMEM70 54968 0 4 7
GSE74703 TMEM70 54968 15 1 20
GSE74704 TMEM70 54968 11 0 9
TCGA TMEM70 54968 50 2 44

Total number of gains: 199; Total number of losses: 28; Total Number of normals: 261.  

 

Somatic mutations of TMEM70:

 

Generating mutation plots.

 

Highly correlated genes for TMEM70:

 

Showing top 20/440 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
TMEM70MRPS280.760009808
TMEM70ENY20.700023807
TMEM70MTFR10.687482808
TMEM70SLC25A320.685417907
TMEM70ASPH0.666851505
TMEM70MTDH0.661308707
TMEM70MRPL150.658859807
TMEM70GGH0.658394706
TMEM70PUF600.651933706
TMEM70ARMC10.651103908
TMEM70RRS10.650953807
TMEM70TGS10.649114706
TMEM70MTERF30.648317706
TMEM70IMPAD10.64745706
TMEM70COPS50.6421861008
TMEM70NIT20.639451605
TMEM70EXOSC40.636509605
TMEM70LAPTM4B0.636379705
TMEM70ATP6V1C10.63367906
TMEM70POLR2K0.633227805

For details and further investigation, click here