| Full name: glutaredoxin 5 | Alias Symbol: PR01238|GRX5 | ||
| Type: protein-coding gene | Cytoband: 14q32.13 | ||
| Entrez ID: 51218 | HGNC ID: HGNC:20134 | Ensembl Gene: ENSG00000182512 | OMIM ID: 609588 |
Screen Evidence:
| |||
Expression of GLRX5:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GLRX5 | 51218 | 221932_s_at | 0.4445 | 0.1009 | |
| GSE20347 | GLRX5 | 51218 | 221932_s_at | 0.6197 | 0.0006 | |
| GSE23400 | GLRX5 | 51218 | 221932_s_at | 0.4791 | 0.0000 | |
| GSE26886 | GLRX5 | 51218 | 221932_s_at | 0.6790 | 0.0002 | |
| GSE29001 | GLRX5 | 51218 | 221932_s_at | 0.6571 | 0.0143 | |
| GSE38129 | GLRX5 | 51218 | 221932_s_at | 0.5006 | 0.0001 | |
| GSE45670 | GLRX5 | 51218 | 221932_s_at | 0.3098 | 0.0525 | |
| GSE53622 | GLRX5 | 51218 | 17047 | 0.5499 | 0.0000 | |
| GSE53624 | GLRX5 | 51218 | 17047 | 0.7802 | 0.0000 | |
| GSE63941 | GLRX5 | 51218 | 221932_s_at | 0.9052 | 0.0143 | |
| GSE77861 | GLRX5 | 51218 | 221932_s_at | 0.3535 | 0.2434 | |
| GSE97050 | GLRX5 | 51218 | A_23_P65370 | 0.4082 | 0.1994 | |
| SRP007169 | GLRX5 | 51218 | RNAseq | 1.2452 | 0.0086 | |
| SRP008496 | GLRX5 | 51218 | RNAseq | 1.1695 | 0.0004 | |
| SRP064894 | GLRX5 | 51218 | RNAseq | 0.3909 | 0.0647 | |
| SRP133303 | GLRX5 | 51218 | RNAseq | 0.5775 | 0.0000 | |
| SRP159526 | GLRX5 | 51218 | RNAseq | 0.7212 | 0.0426 | |
| SRP193095 | GLRX5 | 51218 | RNAseq | 0.1507 | 0.3180 | |
| SRP219564 | GLRX5 | 51218 | RNAseq | 0.2238 | 0.6161 | |
| TCGA | GLRX5 | 51218 | RNAseq | 0.0027 | 0.9592 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by GLRX5 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GLRX5:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GLRX5 | 51218 | 10 | 4 | 16 | |
| GSE20123 | GLRX5 | 51218 | 10 | 3 | 17 | |
| GSE43470 | GLRX5 | 51218 | 8 | 3 | 32 | |
| GSE46452 | GLRX5 | 51218 | 16 | 3 | 40 | |
| GSE47630 | GLRX5 | 51218 | 11 | 8 | 21 | |
| GSE54993 | GLRX5 | 51218 | 3 | 8 | 59 | |
| GSE54994 | GLRX5 | 51218 | 21 | 4 | 28 | |
| GSE60625 | GLRX5 | 51218 | 0 | 2 | 9 | |
| GSE74703 | GLRX5 | 51218 | 6 | 3 | 27 | |
| GSE74704 | GLRX5 | 51218 | 6 | 3 | 11 | |
| TCGA | GLRX5 | 51218 | 30 | 19 | 47 |
Total number of gains: 121; Total number of losses: 60; Total Number of normals: 307.
Somatic mutations of GLRX5:
Generating mutation plots.
Highly correlated genes for GLRX5:
Showing top 20/1905 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GLRX5 | LRRC58 | 0.788912 | 4 | 0 | 4 |
| GLRX5 | EBNA1BP2 | 0.768295 | 3 | 0 | 3 |
| GLRX5 | WDR54 | 0.761317 | 6 | 0 | 6 |
| GLRX5 | CNOT10 | 0.760475 | 3 | 0 | 3 |
| GLRX5 | KTI12 | 0.759226 | 3 | 0 | 3 |
| GLRX5 | INTS10 | 0.755427 | 3 | 0 | 3 |
| GLRX5 | OTUD6B | 0.754897 | 3 | 0 | 3 |
| GLRX5 | VRK1 | 0.752546 | 13 | 0 | 13 |
| GLRX5 | ZNF707 | 0.745614 | 3 | 0 | 3 |
| GLRX5 | SIVA1 | 0.743038 | 13 | 0 | 10 |
| GLRX5 | CENPBD1 | 0.738702 | 4 | 0 | 4 |
| GLRX5 | PDS5B | 0.738533 | 5 | 0 | 5 |
| GLRX5 | LRRC34 | 0.73706 | 3 | 0 | 3 |
| GLRX5 | TIMM9 | 0.736528 | 13 | 0 | 13 |
| GLRX5 | ATG4C | 0.736311 | 3 | 0 | 3 |
| GLRX5 | PSMC1 | 0.730788 | 10 | 0 | 9 |
| GLRX5 | MNAT1 | 0.730724 | 13 | 0 | 13 |
| GLRX5 | PLEKHH1 | 0.725041 | 3 | 0 | 3 |
| GLRX5 | ZNF417 | 0.719167 | 3 | 0 | 3 |
| GLRX5 | ALG1 | 0.719006 | 4 | 0 | 3 |
For details and further investigation, click here
