| Full name: LSM1 homolog, mRNA degradation associated | Alias Symbol: CASM|YJL124C | ||
| Type: protein-coding gene | Cytoband: 8p11.23 | ||
| Entrez ID: 27257 | HGNC ID: HGNC:20472 | Ensembl Gene: ENSG00000175324 | OMIM ID: 607281 |
| Drug and gene relationship at DGIdb | |||
Expression of LSM1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | LSM1 | 27257 | 203534_at | 0.4233 | 0.2480 | |
| GSE20347 | LSM1 | 27257 | 203534_at | 0.6222 | 0.0026 | |
| GSE23400 | LSM1 | 27257 | 203534_at | 0.6069 | 0.0000 | |
| GSE26886 | LSM1 | 27257 | 203534_at | -0.0924 | 0.6673 | |
| GSE29001 | LSM1 | 27257 | 203534_at | 0.4048 | 0.2394 | |
| GSE38129 | LSM1 | 27257 | 203534_at | 0.5718 | 0.0007 | |
| GSE45670 | LSM1 | 27257 | 203534_at | 0.3481 | 0.0342 | |
| GSE63941 | LSM1 | 27257 | 203534_at | -0.6211 | 0.0917 | |
| GSE77861 | LSM1 | 27257 | 203534_at | 0.2119 | 0.3660 | |
| GSE97050 | LSM1 | 27257 | A_23_P20384 | 0.3414 | 0.2328 | |
| SRP007169 | LSM1 | 27257 | RNAseq | 0.5866 | 0.2133 | |
| SRP008496 | LSM1 | 27257 | RNAseq | 0.3459 | 0.3422 | |
| SRP064894 | LSM1 | 27257 | RNAseq | 0.2650 | 0.1798 | |
| SRP133303 | LSM1 | 27257 | RNAseq | 0.7037 | 0.0004 | |
| SRP159526 | LSM1 | 27257 | RNAseq | 0.4373 | 0.2568 | |
| SRP193095 | LSM1 | 27257 | RNAseq | 0.1910 | 0.3231 | |
| SRP219564 | LSM1 | 27257 | RNAseq | -0.1372 | 0.7662 | |
| TCGA | LSM1 | 27257 | RNAseq | 0.0695 | 0.3396 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by LSM1 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of LSM1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | LSM1 | 27257 | 10 | 4 | 16 | |
| GSE20123 | LSM1 | 27257 | 11 | 4 | 15 | |
| GSE43470 | LSM1 | 27257 | 8 | 7 | 28 | |
| GSE46452 | LSM1 | 27257 | 23 | 4 | 32 | |
| GSE47630 | LSM1 | 27257 | 12 | 7 | 21 | |
| GSE54993 | LSM1 | 27257 | 2 | 16 | 52 | |
| GSE54994 | LSM1 | 27257 | 16 | 8 | 29 | |
| GSE60625 | LSM1 | 27257 | 3 | 0 | 8 | |
| GSE74703 | LSM1 | 27257 | 8 | 5 | 23 | |
| GSE74704 | LSM1 | 27257 | 9 | 1 | 10 | |
| TCGA | LSM1 | 27257 | 35 | 25 | 36 |
Total number of gains: 137; Total number of losses: 81; Total Number of normals: 270.
Somatic mutations of LSM1:
Generating mutation plots.
Highly correlated genes for LSM1:
Showing top 20/600 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| LSM1 | MRPL11 | 0.784193 | 3 | 0 | 3 |
| LSM1 | ANKRD54 | 0.780707 | 3 | 0 | 3 |
| LSM1 | PXMP2 | 0.767124 | 3 | 0 | 3 |
| LSM1 | ZMPSTE24 | 0.754121 | 3 | 0 | 3 |
| LSM1 | MRPS7 | 0.743666 | 3 | 0 | 3 |
| LSM1 | BAG4 | 0.741261 | 11 | 0 | 10 |
| LSM1 | ZKSCAN5 | 0.740594 | 3 | 0 | 3 |
| LSM1 | RALGAPB | 0.728872 | 3 | 0 | 3 |
| LSM1 | KDSR | 0.725708 | 3 | 0 | 3 |
| LSM1 | MASTL | 0.720578 | 3 | 0 | 3 |
| LSM1 | SPATA2 | 0.71609 | 5 | 0 | 5 |
| LSM1 | TBX1 | 0.70979 | 3 | 0 | 3 |
| LSM1 | INTS10 | 0.709382 | 6 | 0 | 5 |
| LSM1 | ISY1 | 0.706352 | 3 | 0 | 3 |
| LSM1 | ZDHHC4 | 0.705808 | 4 | 0 | 4 |
| LSM1 | ERLIN2 | 0.705144 | 11 | 0 | 11 |
| LSM1 | TBRG4 | 0.701461 | 3 | 0 | 3 |
| LSM1 | PPP2R3C | 0.699817 | 3 | 0 | 3 |
| LSM1 | ASH2L | 0.697815 | 11 | 0 | 9 |
| LSM1 | TM2D2 | 0.696762 | 7 | 0 | 6 |
For details and further investigation, click here
