| Full name: NADH:ubiquinone oxidoreductase subunit B9 | Alias Symbol: B22|UQOR22|LYRM3 | ||
| Type: protein-coding gene | Cytoband: 8q24.13 | ||
| Entrez ID: 4715 | HGNC ID: HGNC:7704 | Ensembl Gene: ENSG00000147684 | OMIM ID: 601445 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of NDUFB9:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NDUFB9 | 4715 | 222992_s_at | 0.6554 | 0.0107 | |
| GSE26886 | NDUFB9 | 4715 | 222992_s_at | 0.6013 | 0.0036 | |
| GSE45670 | NDUFB9 | 4715 | 222992_s_at | 0.5483 | 0.0041 | |
| GSE53622 | NDUFB9 | 4715 | 69805 | 0.4852 | 0.0000 | |
| GSE53624 | NDUFB9 | 4715 | 69805 | 0.9453 | 0.0000 | |
| GSE63941 | NDUFB9 | 4715 | 222992_s_at | 1.0326 | 0.0222 | |
| GSE77861 | NDUFB9 | 4715 | 222992_s_at | 0.4320 | 0.0134 | |
| GSE97050 | NDUFB9 | 4715 | A_24_P154006 | 0.0981 | 0.7658 | |
| SRP007169 | NDUFB9 | 4715 | RNAseq | 0.1526 | 0.6378 | |
| SRP008496 | NDUFB9 | 4715 | RNAseq | 0.0790 | 0.6790 | |
| SRP064894 | NDUFB9 | 4715 | RNAseq | 0.9470 | 0.0060 | |
| SRP133303 | NDUFB9 | 4715 | RNAseq | 0.6132 | 0.0002 | |
| SRP159526 | NDUFB9 | 4715 | RNAseq | 0.5039 | 0.0650 | |
| SRP193095 | NDUFB9 | 4715 | RNAseq | 0.3239 | 0.0597 | |
| SRP219564 | NDUFB9 | 4715 | RNAseq | 0.4867 | 0.3111 | |
| TCGA | NDUFB9 | 4715 | RNAseq | 0.0686 | 0.1890 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by NDUFB9 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NDUFB9:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NDUFB9 | 4715 | 19 | 0 | 11 | |
| GSE20123 | NDUFB9 | 4715 | 20 | 0 | 10 | |
| GSE43470 | NDUFB9 | 4715 | 22 | 0 | 21 | |
| GSE46452 | NDUFB9 | 4715 | 28 | 0 | 31 | |
| GSE47630 | NDUFB9 | 4715 | 24 | 0 | 16 | |
| GSE54993 | NDUFB9 | 4715 | 0 | 21 | 49 | |
| GSE54994 | NDUFB9 | 4715 | 37 | 1 | 15 | |
| GSE60625 | NDUFB9 | 4715 | 0 | 4 | 7 | |
| GSE74703 | NDUFB9 | 4715 | 19 | 0 | 17 | |
| GSE74704 | NDUFB9 | 4715 | 13 | 0 | 7 | |
| TCGA | NDUFB9 | 4715 | 68 | 1 | 27 |
Total number of gains: 250; Total number of losses: 27; Total Number of normals: 211.
Somatic mutations of NDUFB9:
Generating mutation plots.
Highly correlated genes for NDUFB9:
Showing top 20/1520 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NDUFB9 | MMP11 | 0.763387 | 4 | 0 | 4 |
| NDUFB9 | ACOT13 | 0.741007 | 3 | 0 | 3 |
| NDUFB9 | IMP4 | 0.735527 | 8 | 0 | 8 |
| NDUFB9 | ENY2 | 0.728974 | 9 | 0 | 9 |
| NDUFB9 | NTMT1 | 0.720573 | 5 | 0 | 5 |
| NDUFB9 | PUF60 | 0.720394 | 8 | 0 | 7 |
| NDUFB9 | PSMB3 | 0.719379 | 7 | 0 | 6 |
| NDUFB9 | FOXK1 | 0.718633 | 3 | 0 | 3 |
| NDUFB9 | C20orf27 | 0.713699 | 7 | 0 | 7 |
| NDUFB9 | EXOSC4 | 0.712232 | 9 | 0 | 8 |
| NDUFB9 | LRRC8D | 0.710949 | 6 | 0 | 6 |
| NDUFB9 | HSPD1 | 0.710737 | 7 | 0 | 7 |
| NDUFB9 | CCT3 | 0.705432 | 7 | 0 | 6 |
| NDUFB9 | LAMTOR4 | 0.704598 | 5 | 0 | 5 |
| NDUFB9 | MTERF3 | 0.704251 | 5 | 0 | 5 |
| NDUFB9 | CMSS1 | 0.703598 | 7 | 0 | 6 |
| NDUFB9 | RUVBL1 | 0.702539 | 8 | 0 | 7 |
| NDUFB9 | SLC25A32 | 0.702102 | 7 | 0 | 6 |
| NDUFB9 | CUX1 | 0.700085 | 6 | 0 | 5 |
| NDUFB9 | PFDN2 | 0.700053 | 8 | 0 | 8 |
For details and further investigation, click here
