HNRNPA2B1

 

Full name: heterogeneous nuclear ribonucleoprotein A2/B1 Alias Symbol: 
Type: protein-coding gene Cytoband: 7p15.2
Entrez ID: 3181 HGNC ID: HGNC:5033 Ensembl Gene: ENSG00000122566 OMIM ID: 600124
Drug and gene relationship at DGIdb
Screen Evidence:

 

Expression of HNRNPA2B1:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 HNRNPA2B1 3181 205292_s_at 0.5086 0.0645
GSE20347 HNRNPA2B1 3181 205292_s_at 0.7301 0.0000
GSE23400 HNRNPA2B1 3181 205292_s_at 0.7024 0.0000
GSE26886 HNRNPA2B1 3181 205292_s_at 0.1754 0.4914
GSE29001 HNRNPA2B1 3181 205292_s_at 0.7621 0.0070
GSE38129 HNRNPA2B1 3181 205292_s_at 0.7420 0.0000
GSE45670 HNRNPA2B1 3181 205292_s_at 0.4896 0.0000
GSE53622 HNRNPA2B1 3181 129924 0.4350 0.0000
GSE53624 HNRNPA2B1 3181 129924 0.6769 0.0000
GSE63941 HNRNPA2B1 3181 205292_s_at 0.4870 0.1078
GSE77861 HNRNPA2B1 3181 205292_s_at 0.4350 0.0347
GSE97050 HNRNPA2B1 3181 A_24_P3973 0.4353 0.2659
SRP007169 HNRNPA2B1 3181 RNAseq 0.8065 0.0093
SRP008496 HNRNPA2B1 3181 RNAseq 0.7867 0.0019
SRP064894 HNRNPA2B1 3181 RNAseq 0.3989 0.0081
SRP133303 HNRNPA2B1 3181 RNAseq 0.5627 0.0000
SRP159526 HNRNPA2B1 3181 RNAseq 0.5372 0.0082
SRP193095 HNRNPA2B1 3181 RNAseq 0.2218 0.1010
SRP219564 HNRNPA2B1 3181 RNAseq 0.3791 0.2066
TCGA HNRNPA2B1 3181 RNAseq 0.1301 0.0003

Upregulated datasets: 0; Downregulated datasets: 0.  

 

Survival by HNRNPA2B1 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of HNRNPA2B1:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 HNRNPA2B1 3181 16 1 13
GSE20123 HNRNPA2B1 3181 16 1 13
GSE43470 HNRNPA2B1 3181 4 0 39
GSE46452 HNRNPA2B1 3181 10 2 47
GSE47630 HNRNPA2B1 3181 9 1 30
GSE54993 HNRNPA2B1 3181 0 6 64
GSE54994 HNRNPA2B1 3181 21 2 30
GSE60625 HNRNPA2B1 3181 0 0 11
GSE74703 HNRNPA2B1 3181 4 0 32
GSE74704 HNRNPA2B1 3181 10 1 9
TCGA HNRNPA2B1 3181 55 6 35

Total number of gains: 145; Total number of losses: 20; Total Number of normals: 323.  

 

Somatic mutations of HNRNPA2B1:

 

Generating mutation plots.

 

Highly correlated genes for HNRNPA2B1:

 

Showing top 20/1669 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
HNRNPA2B1CBX30.77035712011
HNRNPA2B1LAPTM4B0.768161909
HNRNPA2B1CENPF0.75887911011
HNRNPA2B1MTBP0.751216404
HNRNPA2B1TOP2A0.75001211011
HNRNPA2B1KIF140.7483811011
HNRNPA2B1KIF4A0.74773310010
HNRNPA2B1UBE2C0.74547411010
HNRNPA2B1TRIP130.74499311011
HNRNPA2B1PNPT10.743609707
HNRNPA2B1PLXNA10.743425909
HNRNPA2B1IPO90.742131807
HNRNPA2B1FANCI0.74041510010
HNRNPA2B1RAD210.738913807
HNRNPA2B1CENPE0.73707911010
HNRNPA2B1MTERF30.736221807
HNRNPA2B1ASPM0.73485311010
HNRNPA2B1HOXC90.732482303
HNRNPA2B1PSMB40.731647909
HNRNPA2B1GNPNAT10.730286303

For details and further investigation, click here