| Full name: DEP domain containing 1B | Alias Symbol: XTP1|BRCC3 | ||
| Type: protein-coding gene | Cytoband: 5q12.1 | ||
| Entrez ID: 55789 | HGNC ID: HGNC:24902 | Ensembl Gene: ENSG00000035499 | OMIM ID: 616073 |
| Drug and gene relationship at DGIdb | |||
Expression of DEPDC1B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DEPDC1B | 55789 | 226980_at | 2.0955 | 0.0439 | |
| GSE26886 | DEPDC1B | 55789 | 226980_at | 0.4986 | 0.1666 | |
| GSE45670 | DEPDC1B | 55789 | 226980_at | 1.6886 | 0.0000 | |
| GSE53622 | DEPDC1B | 55789 | 107368 | 1.6225 | 0.0000 | |
| GSE53624 | DEPDC1B | 55789 | 107368 | 1.8593 | 0.0000 | |
| GSE63941 | DEPDC1B | 55789 | 226980_at | 3.3258 | 0.0000 | |
| GSE77861 | DEPDC1B | 55789 | 226980_at | 0.3746 | 0.0343 | |
| GSE97050 | DEPDC1B | 55789 | A_23_P361419 | 0.4990 | 0.1783 | |
| SRP007169 | DEPDC1B | 55789 | RNAseq | 2.1313 | 0.0001 | |
| SRP008496 | DEPDC1B | 55789 | RNAseq | 1.7857 | 0.0000 | |
| SRP064894 | DEPDC1B | 55789 | RNAseq | 1.6120 | 0.0000 | |
| SRP133303 | DEPDC1B | 55789 | RNAseq | 1.9843 | 0.0000 | |
| SRP159526 | DEPDC1B | 55789 | RNAseq | 1.6068 | 0.0002 | |
| SRP193095 | DEPDC1B | 55789 | RNAseq | 1.0000 | 0.0000 | |
| SRP219564 | DEPDC1B | 55789 | RNAseq | 1.8988 | 0.0068 | |
| TCGA | DEPDC1B | 55789 | RNAseq | 1.1585 | 0.0000 |
Upregulated datasets: 13; Downregulated datasets: 0.
Survival by DEPDC1B expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DEPDC1B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DEPDC1B | 55789 | 0 | 13 | 17 | |
| GSE20123 | DEPDC1B | 55789 | 0 | 13 | 17 | |
| GSE43470 | DEPDC1B | 55789 | 1 | 12 | 30 | |
| GSE46452 | DEPDC1B | 55789 | 0 | 28 | 31 | |
| GSE47630 | DEPDC1B | 55789 | 2 | 17 | 21 | |
| GSE54993 | DEPDC1B | 55789 | 8 | 1 | 61 | |
| GSE54994 | DEPDC1B | 55789 | 1 | 19 | 33 | |
| GSE60625 | DEPDC1B | 55789 | 0 | 0 | 11 | |
| GSE74703 | DEPDC1B | 55789 | 1 | 9 | 26 | |
| GSE74704 | DEPDC1B | 55789 | 0 | 6 | 14 | |
| TCGA | DEPDC1B | 55789 | 6 | 47 | 43 |
Total number of gains: 19; Total number of losses: 165; Total Number of normals: 304.
Somatic mutations of DEPDC1B:
Generating mutation plots.
Highly correlated genes for DEPDC1B:
Showing top 20/1397 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DEPDC1B | GINS4 | 0.84393 | 3 | 0 | 3 |
| DEPDC1B | KIF23 | 0.843467 | 7 | 0 | 7 |
| DEPDC1B | CDCA2 | 0.840659 | 5 | 0 | 5 |
| DEPDC1B | ANLN | 0.830762 | 7 | 0 | 7 |
| DEPDC1B | CENPK | 0.82679 | 8 | 0 | 8 |
| DEPDC1B | NCAPH | 0.824593 | 5 | 0 | 5 |
| DEPDC1B | ATAD2 | 0.820422 | 7 | 0 | 7 |
| DEPDC1B | MELK | 0.815521 | 7 | 0 | 7 |
| DEPDC1B | BORA | 0.80982 | 5 | 0 | 5 |
| DEPDC1B | TTK | 0.798843 | 8 | 0 | 7 |
| DEPDC1B | CCDC86 | 0.798506 | 3 | 0 | 3 |
| DEPDC1B | KIF4A | 0.798427 | 8 | 0 | 8 |
| DEPDC1B | AURKB | 0.796162 | 8 | 0 | 8 |
| DEPDC1B | SPAG5 | 0.794103 | 7 | 0 | 7 |
| DEPDC1B | CDK1 | 0.792617 | 8 | 0 | 8 |
| DEPDC1B | TPX2 | 0.792572 | 8 | 0 | 7 |
| DEPDC1B | RACGAP1 | 0.792034 | 5 | 0 | 5 |
| DEPDC1B | CCNA2 | 0.791453 | 7 | 0 | 7 |
| DEPDC1B | NUF2 | 0.789389 | 8 | 0 | 7 |
| DEPDC1B | CENPA | 0.788976 | 7 | 0 | 7 |
For details and further investigation, click here
