| Full name: homeobox C10 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 12q13.13 | ||
| Entrez ID: 3226 | HGNC ID: HGNC:5122 | Ensembl Gene: ENSG00000180818 | OMIM ID: 605560 |
| Drug and gene relationship at DGIdb | |||
Expression of HOXC10:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | HOXC10 | 3226 | 218959_at | 1.6828 | 0.0261 | |
| GSE20347 | HOXC10 | 3226 | 218959_at | 1.6881 | 0.0000 | |
| GSE23400 | HOXC10 | 3226 | 218959_at | 0.7167 | 0.0000 | |
| GSE26886 | HOXC10 | 3226 | 218959_at | 0.9783 | 0.0019 | |
| GSE29001 | HOXC10 | 3226 | 218959_at | 1.5841 | 0.0001 | |
| GSE38129 | HOXC10 | 3226 | 218959_at | 1.8801 | 0.0000 | |
| GSE45670 | HOXC10 | 3226 | 218959_at | 1.5160 | 0.0003 | |
| GSE53622 | HOXC10 | 3226 | 1338 | 3.4932 | 0.0000 | |
| GSE53624 | HOXC10 | 3226 | 1338 | 3.4410 | 0.0000 | |
| GSE63941 | HOXC10 | 3226 | 218959_at | 3.0749 | 0.0366 | |
| GSE77861 | HOXC10 | 3226 | 218959_at | 0.4967 | 0.0944 | |
| GSE97050 | HOXC10 | 3226 | A_24_P218805 | 1.2494 | 0.1864 | |
| SRP133303 | HOXC10 | 3226 | RNAseq | 3.8063 | 0.0000 | |
| SRP159526 | HOXC10 | 3226 | RNAseq | 6.5171 | 0.0000 | |
| TCGA | HOXC10 | 3226 | RNAseq | 3.1684 | 0.0000 |
Upregulated datasets: 11; Downregulated datasets: 0.
Survival by HOXC10 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of HOXC10:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | HOXC10 | 3226 | 4 | 1 | 25 | |
| GSE20123 | HOXC10 | 3226 | 4 | 1 | 25 | |
| GSE43470 | HOXC10 | 3226 | 3 | 0 | 40 | |
| GSE46452 | HOXC10 | 3226 | 7 | 1 | 51 | |
| GSE47630 | HOXC10 | 3226 | 10 | 2 | 28 | |
| GSE54993 | HOXC10 | 3226 | 0 | 5 | 65 | |
| GSE54994 | HOXC10 | 3226 | 4 | 1 | 48 | |
| GSE60625 | HOXC10 | 3226 | 0 | 0 | 11 | |
| GSE74703 | HOXC10 | 3226 | 3 | 0 | 33 | |
| GSE74704 | HOXC10 | 3226 | 3 | 1 | 16 | |
| TCGA | HOXC10 | 3226 | 15 | 11 | 70 |
Total number of gains: 53; Total number of losses: 23; Total Number of normals: 412.
Somatic mutations of HOXC10:
Generating mutation plots.
Highly correlated genes for HOXC10:
Showing top 20/1029 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| HOXC10 | ACVR1C | 0.763293 | 4 | 0 | 3 |
| HOXC10 | HOXC9 | 0.722208 | 5 | 0 | 5 |
| HOXC10 | HOXA10 | 0.707396 | 9 | 0 | 9 |
| HOXC10 | COL27A1 | 0.701405 | 5 | 0 | 5 |
| HOXC10 | C1QTNF6 | 0.694195 | 3 | 0 | 3 |
| HOXC10 | HOXC13 | 0.683322 | 10 | 0 | 9 |
| HOXC10 | HOXD11 | 0.677171 | 12 | 0 | 9 |
| HOXC10 | RNASE10 | 0.672182 | 3 | 0 | 3 |
| HOXC10 | CDC25B | 0.671342 | 10 | 0 | 10 |
| HOXC10 | NOP56 | 0.671207 | 3 | 0 | 3 |
| HOXC10 | ANLN | 0.668767 | 5 | 0 | 5 |
| HOXC10 | KIF20A | 0.66427 | 10 | 0 | 9 |
| HOXC10 | HOXB7 | 0.663351 | 12 | 0 | 11 |
| HOXC10 | AURKA | 0.662941 | 11 | 0 | 10 |
| HOXC10 | CDKN3 | 0.662501 | 11 | 0 | 10 |
| HOXC10 | MYBL2 | 0.661825 | 11 | 0 | 11 |
| HOXC10 | TROAP | 0.661261 | 10 | 0 | 10 |
| HOXC10 | DHRS13 | 0.658531 | 4 | 0 | 4 |
| HOXC10 | SLC5A12 | 0.657993 | 5 | 0 | 4 |
| HOXC10 | LAPTM4B | 0.655385 | 12 | 0 | 11 |
For details and further investigation, click here
