| Full name: DnaJ heat shock protein family (Hsp40) member B11 | Alias Symbol: EDJ|HEDJ|ERdj3 | ||
| Type: protein-coding gene | Cytoband: 3q27.3 | ||
| Entrez ID: 51726 | HGNC ID: HGNC:14889 | Ensembl Gene: ENSG00000090520 | OMIM ID: 611341 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of DNAJB11:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DNAJB11 | 51726 | 223054_at | 0.7974 | 0.0370 | |
| GSE26886 | DNAJB11 | 51726 | 223054_at | 0.2047 | 0.4789 | |
| GSE45670 | DNAJB11 | 51726 | 223054_at | 0.9327 | 0.0001 | |
| GSE53622 | DNAJB11 | 51726 | 48563 | 1.1011 | 0.0000 | |
| GSE53624 | DNAJB11 | 51726 | 48563 | 1.0571 | 0.0000 | |
| GSE63941 | DNAJB11 | 51726 | 223054_at | -0.0414 | 0.9535 | |
| GSE77861 | DNAJB11 | 51726 | 223054_at | 0.7089 | 0.0221 | |
| GSE97050 | DNAJB11 | 51726 | A_23_P166899 | 1.2248 | 0.0555 | |
| SRP007169 | DNAJB11 | 51726 | RNAseq | 2.3191 | 0.0001 | |
| SRP008496 | DNAJB11 | 51726 | RNAseq | 2.5899 | 0.0000 | |
| SRP064894 | DNAJB11 | 51726 | RNAseq | 1.2462 | 0.0000 | |
| SRP133303 | DNAJB11 | 51726 | RNAseq | 1.5656 | 0.0000 | |
| SRP159526 | DNAJB11 | 51726 | RNAseq | 1.5508 | 0.0000 | |
| SRP193095 | DNAJB11 | 51726 | RNAseq | 0.7957 | 0.0000 | |
| SRP219564 | DNAJB11 | 51726 | RNAseq | 1.2750 | 0.0096 | |
| TCGA | DNAJB11 | 51726 | RNAseq | 0.2516 | 0.0000 |
Upregulated datasets: 8; Downregulated datasets: 0.
Survival by DNAJB11 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DNAJB11:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DNAJB11 | 51726 | 24 | 0 | 6 | |
| GSE20123 | DNAJB11 | 51726 | 24 | 0 | 6 | |
| GSE43470 | DNAJB11 | 51726 | 23 | 0 | 20 | |
| GSE46452 | DNAJB11 | 51726 | 19 | 1 | 39 | |
| GSE47630 | DNAJB11 | 51726 | 27 | 2 | 11 | |
| GSE54993 | DNAJB11 | 51726 | 1 | 19 | 50 | |
| GSE54994 | DNAJB11 | 51726 | 40 | 0 | 13 | |
| GSE60625 | DNAJB11 | 51726 | 0 | 6 | 5 | |
| GSE74703 | DNAJB11 | 51726 | 20 | 0 | 16 | |
| GSE74704 | DNAJB11 | 51726 | 16 | 0 | 4 | |
| TCGA | DNAJB11 | 51726 | 77 | 0 | 19 |
Total number of gains: 271; Total number of losses: 28; Total Number of normals: 189.
Somatic mutations of DNAJB11:
Generating mutation plots.
Highly correlated genes for DNAJB11:
Showing top 20/1941 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DNAJB11 | SPAG5 | 0.804967 | 6 | 0 | 6 |
| DNAJB11 | MTBP | 0.797642 | 5 | 0 | 5 |
| DNAJB11 | SCARB1 | 0.794491 | 3 | 0 | 3 |
| DNAJB11 | LRRC58 | 0.790406 | 4 | 0 | 4 |
| DNAJB11 | TACC3 | 0.788415 | 5 | 0 | 5 |
| DNAJB11 | CENPA | 0.787535 | 5 | 0 | 5 |
| DNAJB11 | RFC4 | 0.785865 | 7 | 0 | 7 |
| DNAJB11 | U2SURP | 0.784352 | 4 | 0 | 4 |
| DNAJB11 | PTRH2 | 0.781717 | 6 | 0 | 6 |
| DNAJB11 | CLPTM1L | 0.780962 | 6 | 0 | 6 |
| DNAJB11 | ISG20L2 | 0.780774 | 5 | 0 | 5 |
| DNAJB11 | HPRT1 | 0.780422 | 5 | 0 | 5 |
| DNAJB11 | CENPN | 0.778958 | 6 | 0 | 6 |
| DNAJB11 | GPRIN1 | 0.777935 | 3 | 0 | 3 |
| DNAJB11 | MRPL47 | 0.77442 | 8 | 0 | 7 |
| DNAJB11 | NCAPG | 0.771969 | 3 | 0 | 3 |
| DNAJB11 | ATR | 0.771889 | 6 | 0 | 6 |
| DNAJB11 | FZD6 | 0.770749 | 4 | 0 | 4 |
| DNAJB11 | CENPE | 0.764833 | 5 | 0 | 5 |
| DNAJB11 | KIF14 | 0.764094 | 6 | 0 | 6 |
For details and further investigation, click here
