| Full name: membrane bound O-acyltransferase domain containing 7 | Alias Symbol: BB1|hMBOA-7|LPLAT | ||
| Type: protein-coding gene | Cytoband: 19q13.42 | ||
| Entrez ID: 79143 | HGNC ID: HGNC:15505 | Ensembl Gene: ENSG00000125505 | OMIM ID: 606048 |
| Drug and gene relationship at DGIdb | |||
Expression of MBOAT7:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MBOAT7 | 79143 | 209179_s_at | 0.6023 | 0.0427 | |
| GSE20347 | MBOAT7 | 79143 | 209179_s_at | -0.0581 | 0.5789 | |
| GSE23400 | MBOAT7 | 79143 | 209179_s_at | 0.2198 | 0.0001 | |
| GSE26886 | MBOAT7 | 79143 | 209179_s_at | 0.6762 | 0.0001 | |
| GSE29001 | MBOAT7 | 79143 | 209179_s_at | -0.0365 | 0.8639 | |
| GSE38129 | MBOAT7 | 79143 | 209179_s_at | 0.1213 | 0.1705 | |
| GSE45670 | MBOAT7 | 79143 | 209179_s_at | 0.2244 | 0.2120 | |
| GSE53622 | MBOAT7 | 79143 | 48204 | 0.0699 | 0.3183 | |
| GSE53624 | MBOAT7 | 79143 | 48204 | 0.2803 | 0.0000 | |
| GSE63941 | MBOAT7 | 79143 | 209179_s_at | -0.1999 | 0.6991 | |
| GSE77861 | MBOAT7 | 79143 | 209179_s_at | 0.0418 | 0.8182 | |
| GSE97050 | MBOAT7 | 79143 | A_23_P208516 | 0.2254 | 0.2536 | |
| SRP007169 | MBOAT7 | 79143 | RNAseq | -1.2170 | 0.0002 | |
| SRP008496 | MBOAT7 | 79143 | RNAseq | -0.9861 | 0.0000 | |
| SRP064894 | MBOAT7 | 79143 | RNAseq | 1.0091 | 0.0003 | |
| SRP133303 | MBOAT7 | 79143 | RNAseq | 0.4192 | 0.0487 | |
| SRP159526 | MBOAT7 | 79143 | RNAseq | 0.7410 | 0.0008 | |
| SRP193095 | MBOAT7 | 79143 | RNAseq | 0.3656 | 0.0117 | |
| SRP219564 | MBOAT7 | 79143 | RNAseq | 0.0602 | 0.8407 | |
| TCGA | MBOAT7 | 79143 | RNAseq | 0.0064 | 0.9026 |
Upregulated datasets: 1; Downregulated datasets: 1.
Survival by MBOAT7 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MBOAT7:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MBOAT7 | 79143 | 3 | 4 | 23 | |
| GSE20123 | MBOAT7 | 79143 | 3 | 3 | 24 | |
| GSE43470 | MBOAT7 | 79143 | 2 | 11 | 30 | |
| GSE46452 | MBOAT7 | 79143 | 45 | 1 | 13 | |
| GSE47630 | MBOAT7 | 79143 | 8 | 6 | 26 | |
| GSE54993 | MBOAT7 | 79143 | 17 | 4 | 49 | |
| GSE54994 | MBOAT7 | 79143 | 4 | 14 | 35 | |
| GSE60625 | MBOAT7 | 79143 | 9 | 0 | 2 | |
| GSE74703 | MBOAT7 | 79143 | 2 | 7 | 27 | |
| GSE74704 | MBOAT7 | 79143 | 3 | 1 | 16 | |
| TCGA | MBOAT7 | 79143 | 19 | 15 | 62 |
Total number of gains: 115; Total number of losses: 66; Total Number of normals: 307.
Somatic mutations of MBOAT7:
Generating mutation plots.
Highly correlated genes for MBOAT7:
Showing top 20/641 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MBOAT7 | MSTO1 | 0.741983 | 3 | 0 | 3 |
| MBOAT7 | NACC1 | 0.713107 | 3 | 0 | 3 |
| MBOAT7 | FOXRED2 | 0.711977 | 4 | 0 | 4 |
| MBOAT7 | IMP4 | 0.706011 | 4 | 0 | 3 |
| MBOAT7 | FAT1 | 0.702284 | 3 | 0 | 3 |
| MBOAT7 | FKBP10 | 0.69741 | 3 | 0 | 3 |
| MBOAT7 | HOXA10 | 0.692421 | 3 | 0 | 3 |
| MBOAT7 | CDK18 | 0.689356 | 4 | 0 | 3 |
| MBOAT7 | MAP3K2 | 0.678591 | 4 | 0 | 3 |
| MBOAT7 | MAP3K11 | 0.677623 | 5 | 0 | 4 |
| MBOAT7 | CHTF18 | 0.675385 | 3 | 0 | 3 |
| MBOAT7 | GMPS | 0.671021 | 4 | 0 | 3 |
| MBOAT7 | PHC2 | 0.669288 | 4 | 0 | 4 |
| MBOAT7 | RAC3 | 0.667808 | 3 | 0 | 3 |
| MBOAT7 | SCYL1 | 0.665586 | 4 | 0 | 3 |
| MBOAT7 | JMJD4 | 0.665184 | 4 | 0 | 3 |
| MBOAT7 | CHST12 | 0.662704 | 5 | 0 | 4 |
| MBOAT7 | RNF4 | 0.661971 | 3 | 0 | 3 |
| MBOAT7 | STRA6 | 0.661591 | 4 | 0 | 4 |
| MBOAT7 | APOE | 0.660284 | 4 | 0 | 3 |
For details and further investigation, click here
