| Full name: heparan sulfate-glucosamine 3-sulfotransferase 3A1 | Alias Symbol: 3OST3A1|30ST3A1 | ||
| Type: protein-coding gene | Cytoband: 17p12 | ||
| Entrez ID: 9955 | HGNC ID: HGNC:5196 | Ensembl Gene: ENSG00000153976 | OMIM ID: 604057 |
| Drug and gene relationship at DGIdb | |||
Expression of HS3ST3A1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | HS3ST3A1 | 9955 | 219985_at | -0.3189 | 0.8342 | |
| GSE20347 | HS3ST3A1 | 9955 | 219985_at | -0.5406 | 0.1649 | |
| GSE23400 | HS3ST3A1 | 9955 | 219985_at | 0.0355 | 0.7672 | |
| GSE26886 | HS3ST3A1 | 9955 | 219985_at | -0.0295 | 0.9491 | |
| GSE29001 | HS3ST3A1 | 9955 | 219985_at | -0.8398 | 0.1832 | |
| GSE38129 | HS3ST3A1 | 9955 | 219985_at | -0.0606 | 0.8706 | |
| GSE45670 | HS3ST3A1 | 9955 | 219985_at | 0.6028 | 0.2305 | |
| GSE53622 | HS3ST3A1 | 9955 | 49441 | 0.0937 | 0.6714 | |
| GSE53624 | HS3ST3A1 | 9955 | 49441 | -0.3704 | 0.0236 | |
| GSE63941 | HS3ST3A1 | 9955 | 219985_at | -2.5818 | 0.0185 | |
| GSE77861 | HS3ST3A1 | 9955 | 219985_at | -0.2430 | 0.5366 | |
| GSE97050 | HS3ST3A1 | 9955 | A_23_P66525 | 0.6931 | 0.2796 | |
| SRP007169 | HS3ST3A1 | 9955 | RNAseq | -1.5048 | 0.0054 | |
| SRP064894 | HS3ST3A1 | 9955 | RNAseq | 0.0110 | 0.9794 | |
| SRP133303 | HS3ST3A1 | 9955 | RNAseq | 0.1370 | 0.6039 | |
| SRP159526 | HS3ST3A1 | 9955 | RNAseq | -1.0845 | 0.0497 | |
| SRP193095 | HS3ST3A1 | 9955 | RNAseq | 0.0376 | 0.9156 | |
| SRP219564 | HS3ST3A1 | 9955 | RNAseq | 0.5310 | 0.4545 | |
| TCGA | HS3ST3A1 | 9955 | RNAseq | 0.7825 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 3.
Survival by HS3ST3A1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of HS3ST3A1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | HS3ST3A1 | 9955 | 3 | 3 | 24 | |
| GSE20123 | HS3ST3A1 | 9955 | 3 | 4 | 23 | |
| GSE43470 | HS3ST3A1 | 9955 | 2 | 5 | 36 | |
| GSE46452 | HS3ST3A1 | 9955 | 34 | 1 | 24 | |
| GSE47630 | HS3ST3A1 | 9955 | 7 | 1 | 32 | |
| GSE54993 | HS3ST3A1 | 9955 | 3 | 2 | 65 | |
| GSE54994 | HS3ST3A1 | 9955 | 6 | 6 | 41 | |
| GSE60625 | HS3ST3A1 | 9955 | 4 | 0 | 7 | |
| GSE74703 | HS3ST3A1 | 9955 | 2 | 4 | 30 | |
| GSE74704 | HS3ST3A1 | 9955 | 2 | 2 | 16 | |
| TCGA | HS3ST3A1 | 9955 | 17 | 22 | 57 |
Total number of gains: 83; Total number of losses: 50; Total Number of normals: 355.
Somatic mutations of HS3ST3A1:
Generating mutation plots.
Highly correlated genes for HS3ST3A1:
Showing top 20/99 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| HS3ST3A1 | GLIS3 | 0.740454 | 3 | 0 | 3 |
| HS3ST3A1 | ZBED6 | 0.724184 | 3 | 0 | 3 |
| HS3ST3A1 | USP4 | 0.669102 | 3 | 0 | 3 |
| HS3ST3A1 | SCAMP4 | 0.663504 | 4 | 0 | 4 |
| HS3ST3A1 | SETD4 | 0.651672 | 3 | 0 | 3 |
| HS3ST3A1 | SLC16A2 | 0.648869 | 3 | 0 | 3 |
| HS3ST3A1 | DSTYK | 0.64794 | 3 | 0 | 3 |
| HS3ST3A1 | TUBGCP3 | 0.646493 | 4 | 0 | 3 |
| HS3ST3A1 | GAS6 | 0.638553 | 4 | 0 | 3 |
| HS3ST3A1 | EWSR1 | 0.637422 | 3 | 0 | 3 |
| HS3ST3A1 | DHDDS | 0.633706 | 3 | 0 | 3 |
| HS3ST3A1 | TMEM220 | 0.625635 | 3 | 0 | 3 |
| HS3ST3A1 | RAB23 | 0.62464 | 3 | 0 | 3 |
| HS3ST3A1 | ALDH7A1 | 0.622963 | 3 | 0 | 3 |
| HS3ST3A1 | MID1IP1 | 0.622234 | 3 | 0 | 3 |
| HS3ST3A1 | TEX2 | 0.620636 | 3 | 0 | 3 |
| HS3ST3A1 | UFM1 | 0.619795 | 5 | 0 | 3 |
| HS3ST3A1 | TADA2B | 0.610289 | 3 | 0 | 3 |
| HS3ST3A1 | SHISA5 | 0.60919 | 4 | 0 | 3 |
| HS3ST3A1 | WDR11 | 0.608725 | 3 | 0 | 3 |
For details and further investigation, click here
