| Full name: transmembrane protein 220 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 17p13.1 | ||
| Entrez ID: 388335 | HGNC ID: HGNC:33757 | Ensembl Gene: ENSG00000187824 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of TMEM220:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TMEM220 | 388335 | 229693_at | -1.0337 | 0.1295 | |
| GSE26886 | TMEM220 | 388335 | 229693_at | -1.6489 | 0.0001 | |
| GSE45670 | TMEM220 | 388335 | 229693_at | -1.3715 | 0.0002 | |
| GSE53622 | TMEM220 | 388335 | 88001 | -0.6583 | 0.0000 | |
| GSE53624 | TMEM220 | 388335 | 88001 | -0.8657 | 0.0000 | |
| GSE63941 | TMEM220 | 388335 | 229693_at | -3.7372 | 0.0000 | |
| GSE77861 | TMEM220 | 388335 | 229693_at | -0.6006 | 0.0769 | |
| GSE97050 | TMEM220 | 388335 | A_33_P3266639 | -0.2407 | 0.2657 | |
| SRP007169 | TMEM220 | 388335 | RNAseq | -1.6187 | 0.0076 | |
| SRP064894 | TMEM220 | 388335 | RNAseq | -0.9896 | 0.0000 | |
| SRP133303 | TMEM220 | 388335 | RNAseq | -0.9104 | 0.0000 | |
| SRP159526 | TMEM220 | 388335 | RNAseq | -1.5514 | 0.0000 | |
| SRP193095 | TMEM220 | 388335 | RNAseq | -0.8297 | 0.0000 | |
| SRP219564 | TMEM220 | 388335 | RNAseq | -0.7461 | 0.1192 | |
| TCGA | TMEM220 | 388335 | RNAseq | -1.0300 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 6.
Survival by TMEM220 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TMEM220:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TMEM220 | 388335 | 3 | 4 | 23 | |
| GSE20123 | TMEM220 | 388335 | 3 | 5 | 22 | |
| GSE43470 | TMEM220 | 388335 | 2 | 5 | 36 | |
| GSE46452 | TMEM220 | 388335 | 34 | 1 | 24 | |
| GSE47630 | TMEM220 | 388335 | 7 | 1 | 32 | |
| GSE54993 | TMEM220 | 388335 | 3 | 4 | 63 | |
| GSE54994 | TMEM220 | 388335 | 5 | 7 | 41 | |
| GSE60625 | TMEM220 | 388335 | 4 | 0 | 7 | |
| GSE74703 | TMEM220 | 388335 | 2 | 3 | 31 | |
| GSE74704 | TMEM220 | 388335 | 2 | 2 | 16 | |
| TCGA | TMEM220 | 388335 | 18 | 20 | 58 |
Total number of gains: 83; Total number of losses: 52; Total Number of normals: 353.
Somatic mutations of TMEM220:
Generating mutation plots.
Highly correlated genes for TMEM220:
Showing top 20/1231 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TMEM220 | USP9Y | 0.796831 | 3 | 0 | 3 |
| TMEM220 | SRGAP2 | 0.778556 | 3 | 0 | 3 |
| TMEM220 | PDCD4 | 0.760691 | 4 | 0 | 4 |
| TMEM220 | DHDDS | 0.754257 | 3 | 0 | 3 |
| TMEM220 | FOXO3 | 0.752663 | 4 | 0 | 4 |
| TMEM220 | RERE | 0.751513 | 3 | 0 | 3 |
| TMEM220 | TDRD3 | 0.749176 | 5 | 0 | 5 |
| TMEM220 | KRTAP1-3 | 0.748776 | 3 | 0 | 3 |
| TMEM220 | ZFY | 0.74786 | 3 | 0 | 3 |
| TMEM220 | RRAGB | 0.741426 | 3 | 0 | 3 |
| TMEM220 | SETD7 | 0.737541 | 3 | 0 | 3 |
| TMEM220 | GYPC | 0.733892 | 5 | 0 | 5 |
| TMEM220 | DHRS12 | 0.733174 | 4 | 0 | 4 |
| TMEM220 | MYD88 | 0.73072 | 3 | 0 | 3 |
| TMEM220 | SUSD1 | 0.726256 | 3 | 0 | 3 |
| TMEM220 | ARPC2 | 0.726066 | 4 | 0 | 4 |
| TMEM220 | ACAA1 | 0.718217 | 6 | 0 | 6 |
| TMEM220 | STK19 | 0.71363 | 4 | 0 | 4 |
| TMEM220 | KDM5D | 0.712296 | 4 | 0 | 4 |
| TMEM220 | LRRFIP2 | 0.711709 | 7 | 0 | 6 |
For details and further investigation, click here
